... Germany;2Rutgers University,Department of Chemistry and Chemical Biology, Piscataway, NJ, USACalcitonin (Ct) is a 32-residue peptide hormone that is mainly known for its hypocalcemic effect and ... acids and standard protection of the side-chains[Asp(OtBu), Glu(OtBu), G ln(Trt), Cys( Trt), H is( Trt),Lys(Boc), Tyr(tBu) and Thr(tBu)], with the exception of residues Lys21 and Asp17 of the cyclic ... N,N¢-diisopropylethylamine; DMS, dimethylsulfide; EDT,ethanedithiol; hCt, human calcitonin; MBHA, 4-methyl benzhydryl-amine resin; Mtt, 4-methyltrityl; Pip, 2-phenylisopropyl;OFm, fluoren-9-yl methylester; sCt, salmon...