Báo cáo y học: " Polysaccharides from the root of Angelica sinensis protect bone marrow and gastrointestinal tissues against the cytotoxicity of cyclophosphamide in mice
... reserved Research paper Polysaccharides from the root of Angelica sinensis protect bone marrow and gastrointestinal tissues against the cytotoxicity of cyclophosphamide in mice Marco K. C. Hui, ... marrow and the gastrointestinal tissues from the cytotoxicity of CY in mice. We also profiled the changes of the expression of g...
Ngày tải lên: 02/11/2012, 10:19
... assay, indicating the equilibrium position for the N-acetylorni- thine:ornithine mixture was approximately 2 : 1 as deter- mined by integration of the hydrogens of the a-acetyl CH 3 group of the N-acetylated ... (2S,3R)-3-hydroxy-N-acetylarginine is shown boxed. Scheme 2. The role of OAT (ARGJ) in the biosynthesis of arginine. ORF6 carries out the same reaction. T...
Ngày tải lên: 08/03/2014, 22:20
... erritins. Thus, H c hains predominate in spleen and liver at variance with thepresenceofL chainsinthesameorgansofmammals[6]. Interestingly, a study of cold-inducible gene expression of rainbow ... protein indicated for the N-terminal peptide MDSQVR a value of m/z 777, which points t o the presence of acetylme thionine. This r esidue is commonly found in the N-terminus of...
Ngày tải lên: 08/03/2014, 23:20
Báo cáo Y học: Hemocyanin from the keyhole limpet Megathura crenulata (KLH) carries a novel type of N-glycans with Gal(b1–6)Man-motifs doc
... Man shown by methylation analysis. Consid- ering the linkage position of b-Gal residues found in the other compounds and the common route of biosynthesis of N-linked glycans, it may be postulated ... N-glycans. Hemocyanins are oxygen-transporting proteins found in many arthropod and mollusc species [1]. Binding of oxygen is mediated by binuclear copper-binding sites, res...
Ngày tải lên: 31/03/2014, 08:20
Báo cáo y học: " WT1 PEPTIDE VACCINATION IN COMBINATION WITH IMATINIB THERAPY FOR A PATIENT WITH CML IN THE CHRONIC PHASE"
... peptides. An in vitro study as to the cytotoxicity of lymphocytes induced by mixed lymphocyte peptide culture demonstrated that cultured lymphocytes possessed cytotoxicity against WT1 expressing leukemia ... Percent cytotoxicity of the assay was calculated by the following formula. : % cytotoxicity = [(absolute number of viable target cells in the tube containing t...
Ngày tải lên: 26/10/2012, 09:39
Báo cáo khoa học: Peptides from purified soybean b-conglycinin inhibit fatty acid synthase by interaction with the thioesterase catalytic domain pot
... near physiologic conditions, meaning that they bind to the unoccupied enzyme and reduce substrate turnover. The TE domain coordinates the terminal step of fatty acid synthesis by hydrolyzing palmitate ... accommodate relatively large inhibitors and that the TE domain is a better target for these types of peptide inhibitors. To confirm the binding of these peptide inhibitors...
Ngày tải lên: 06/03/2014, 09:22
Báo cáo Y học: A novel DNA repair enzyme containing RNA recognition, G-patch and specific splicing factor 45-like motifs in the protozoan parasite Toxoplasma gondii potx
... tachyzoites. The tachyzoites differentiate into encysted bradyzoites in response to the immune system attack during disease progression. They will remain in the brain and other organs during the lifetime ... of infected hosts. The reactivation of encysted bradyzoites into actively replicating and cytolytic tachyzoites can trigger a disease with severe clinical syndromes...
Ngày tải lên: 08/03/2014, 22:20
Báo cáo Y học: GNA33 from Neisseria meningitidis serogroup B encodes a membrane-bound lytic transglycosylase (MltA) pdf
... cleave the polysaccharide backbone of the peptidoglycan layer, lytic transglycosylases are thought to play a role in synthesis and degradation of the murein sacculus. It has been proposed that lytic transglycosylases ... lysozyme where the glycosyl moiety is transferred to H 2 O, cleavage by lytic transglycosylases is followed by an intramolecular transgly- cosylation [10]. I...
Ngày tải lên: 31/03/2014, 23:20
Báo cáo y học: "Strict glycaemic control in patients hospitalised in a mixed medical and surgical intensive care unit: a randomised clinical trial"
... mortality at 28 days was 32.4% (81 of 250) in thestandard insulin group and 36.6% (93 of 254) in the intensiveinsulin group. ICU mortality was similar for patients of thestandard insulin group and in ... reduction in the rate of ICU-acquired infections:33.2% in the standard insulin therapy group compared with27.17% in the intensive insulin therapy group (RR: 0....
Ngày tải lên: 25/10/2012, 10:35
Báo cáo y học: "Primary lower limb lymphedema: a focus on its functional, social and emotional impac"
... found interesting to review known cases of lymphe-dema in the island of Crete. These reports f ocu s on two cases of primary lower limb lymphedema, by discussing the overall physical and mental ... lymphedema, the same as in other chronic illnesses and conditions. Assessing not only the severity of the physical limitation but also the re-lated psychosocial dimensio...
Ngày tải lên: 25/10/2012, 11:40