Molecular Farming of Antibodies in Plants
Molecular Farming of Antibodies in Plants
... 3 Molecular Farming of Antibodies in Plants 37 rearrangements of the germ-line immunoglobulin genes. This part of the molecule is responsible for antigen recognition and binding. The remainder ... chains are shown in gray and light chains in pink.Solidblack lines indicate continuation of the polypeptide backbone (simple lines indicate the constant parts of the antibody...
Ngày tải lên: 25/10/2013, 05:20
Báo cáo y học: "Long Term Persistence of IgE Anti-Influenza Virus Antibodies in Pediatric and Adult Serum Post Vaccination with Influenza Virus Vaccine"
... One software BioRad, Hercules, CA). Cytokine determination Serum cytokines [Interleukin-2 (IL-2), Interferon gamma (IFN-γ), Interleukin-4 (IL-4), Interluekin-10 (IL-10)] were determined ... IgE specific Influenza virus antibodies were increased after influenza vaccination in mice [17]. Interestingly, low levels of total Influenza virus-specific antibody secreting cells ... history of...
Ngày tải lên: 25/10/2012, 11:10
Báo cáo y học: "Advances in Molecular Diagnosis of HBV Infection and Drug Resistance"
... two include the substitution of methionine (M) by the amino acids isoleucine (I) or valine (V) in the YMDD motif (C domain) at position rtM204V/I. In the majority of cases, these mutations in ... yes intermediate low low yes Florescence nd intermediate intermediate no intermediate intermediate intermediate yes MALDI-TOF <5% intermediate intermediate No intermediate intermediate ....
Ngày tải lên: 03/11/2012, 09:41
Molecular Biology of Secondary Metabolism - Case Study for Glycyrrhiza Plants
... needed to feed an increasing world population. In addition, it shows the contribution of this strategy to the development of plants with biofarming potential in the frame of a high demand of natural ... the possibility of intein-mediated protein trans-splicing for limiting the environmental impact of herbicide resistance, by separating parts of the gene in plastid and nu...
Ngày tải lên: 25/10/2013, 05:20
Regulating Phytonutrient Levels in Plants – Toward Modification of Plant Metabolism for Human Health
... others being delphinidin, peonidin, pelargonidin, petunidin, and malvidin. Of the flavonols, quercetin, kaempferol, myricetin, and isorhamnetin are common in fruits, quercetin being the predominant ... modifying a biosynthetic pathway to increase amounts of desirable phytonutrients are available: (1) manipulation of pathway flux, includ- ing increasing, preventing, or redirecting flux in...
Ngày tải lên: 25/10/2013, 05:20
Tài liệu Báo cáo khoa học: EGF receptor in relation to tumor development: molecular basis of responsiveness of cancer cells to EGFR-targeting tyrosine kinase inhibitors docx
... domain, a transmembrane domain and an intracellular tyrosine kinase domain. The binding of a ligand to the extracel- lular domain of the EGFR induces receptor dimeriza- tion, activation of the intracellular ... carcinomas; IAP, inhibitor of apoptosis protein; JNK, c-Jun NH 2 -terminal kinase; KIP, kinase inhibitor proteins; MEK, MAPK ⁄ ERK kinase; MKK, MAPK kinase; MKP-1, mitogen-acti...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: Exposure of IgG to an acidic environment results in molecular modifications and in enhanced protective activity in sepsis doc
... same antigen– antibody interaction in the presence of increasing concentrations of NaCl. In both experiments, binding intensities are represented in RU, and each data point shows the mean value ... appearance of a number of novel antigen-binding specificities (Fig. 1B). Enhanced binding of low-pH buffer-exposed IVIg to recombinant human interferon-c (IFN-c) and other self-antig...
Ngày tải lên: 16/02/2014, 15:20
Tài liệu Báo cáo khoa học: Molecular defect of isovaleryl-CoA dehydrogenase in the skunk mutant of silkworm, Bombyx mori ppt
... becom- ing pupae in about a week after spinning (Fig. 1B). Isovaleric acid seems to be the cause of prepupal lethality because injection of isovaleric acid into normal spinning larva induces ... the sku mutant accumulates branched-chain amino acids in haemolymph, this mutant may be useful in the investigation of unique branched-chain amino acid catabolism in insects. Abbreviatio...
Ngày tải lên: 18/02/2014, 04:20
Tài liệu Báo cáo khoa học: Molecular determinants of ligand specificity in family 11 carbohydrate binding modules – an NMR, X-ray crystallography and computational chemistry approach doc
... addition of CtCBM11. In general, a progressive line broadening of all the cellohexaose protons was observed during titration with increasing amounts of protein, which can be understood as a result of ... (Fig. 1III–V), which could indicate that the corre- sponding hydroxyl groups are involved in protein binding. The results for the linebroadening measurements of protons H1a in...
Ngày tải lên: 18/02/2014, 17:20
Tài liệu Báo cáo khoa học: Molecular aspects of rheumatoid arthritis: chemokines in the joints of patients pdf
... chemokines stimu- lated mainly by in ammatory cytokines, including IL-1b, TNF-a and IFN-c. (B) Chemokines expressed in the joint recruit leukocytes into the joints. In addition to functioning in ... examination of affected rheu- matoid joints reveals extensive RANTES ⁄ CCL5 expression in the synovial lining and sublining layers [22]. The expression of RANTES ⁄ CCL5 in cultured...
Ngày tải lên: 18/02/2014, 18:20