... Int. J. Med. Sci. 2010, 7 http://www.medsci.org 142DARinv mediated ligation of the [TcT-N-propyl]-N- glycyl-GdSc2@C80n with the N-(2-Aminopropyl )-4 -( 6- (pyrimidine-2-yl )-1 ,2,4,5-tetrazine-3-yl)benzamide ... Ligation of the tetrazine diene compound N-(2-Amino-propyl )-4 -( 6-( pyrimidine-2-yl )-1 ,2,4,5-tetrazine-3-yl)benzamide (4) with the NLS-Cys peptide and coupling to the Cys-CPP via disulfide bridge ... running in both positive- and negative-ion modes (Biflex III, Bruker, Germany). Synthesis of the diene compound N-(2-Aminopropyl )-4 - ( 6-( pyrimidine-2-yl )-1 ,2,4,5-tetrazine-3-yl)benzamide (4) 4-( 6-( pyrimidine-2-yl )-1 ,4-dihydro-1,2,4,5-tetrazine-3-yl)benzoic...