... No flavin compounds were bound to the a1 subunit of PDH1, though it did contain one ADP- binding motif. This suggests the ADP-binding motif in the a1 subunit mediates the observed ATP binding, and ... analysis. This means that ATG, which was situated 7 bp down- stream from the 5¢-terminus of the predicted ORF, is the proper initial codon for the a1 gene. The N-terminal am...
Ngày tải lên: 20/02/2014, 01:20
... resulted in this panel, which is supposed to debate the necessity of continuing work in this area rather than to debate technical issues in the area. And yet if this problem has been solved, where ... for all the Michigan doctors and Pennsylvania dentists, produced a list of all the people who were either doctors or dentists and who lived in either Michigan or Pennsy...
Ngày tải lên: 21/02/2014, 20:20
Processing Fluency and Aesthetic Pleasure: Is Beauty in the Perceiver''''s Processing Experience? pptx
... instead from the processing experi- ences of the perceiver. Is beauty therefore in the eye of the beholder? In a sense it is, if folk wisdom thinks of the eye as the perceptual processes of the beholder. However, ... in higher percep- tual fiuency, and training in arts gives meaning to com- plex structures in paintings, poems, or music, which results in an additi...
Ngày tải lên: 16/03/2014, 18:20
Báo cáo khoa học: Oxidative stress is involved in the permeabilization of the inner membrane of brain mitochondria exposed to hypoxia/reoxygenation and low micromolar Ca2+ Lorenz Schild1 and Georg Reiser2 doc
... sug- gests that the mitochondrial injury is caused by open- ing of the mPTP. There is evidence that ADP inhibits opening of the mPTP by occupying binding sites located in the inner and outer ... relevance in brain, because in this tissue glucose is metabolized providing the NADH-yielding substrate pyruvate. Under these con- ditions, some succinate is formed by the ci...
Ngày tải lên: 16/03/2014, 22:20
Báo cáo khoa học: An E3 ubiquitin ligase, Synoviolin, is involved in the degradation of immature nicastrin, and regulates the production of amyloid b-protein doc
... polyglu- tamine-expanded huntingtin [18], the tumor suppressor gene p53 [19] and Parkin-associated endothelin recep- tor-like receptor [20]. In this study, we addressed whether Synoviolin is involved in the degradation ... Supporting Information). We also determined the levels of c-secre- tase-unrelated ER protein (calnexin) and cytoskeleton protein (tubulin) in these cells as...
Ngày tải lên: 23/03/2014, 04:20
Báo cáo khoa học: Protein kinase Ch activity is involved in the 2,3,7,8tetrachlorodibenzo-p-dioxin-induced signal transduction pathway leading to apoptosis in L-MAT, a human lymphoblastic T-cell line potx
... lymphoblastic T-cell line. In this report, we provide the following evidence that the protein kinase C (PKC)h activity is func- tionally involved in the AhR-independent signal transduction mechanism that ... apoptosis in mouse spleen cells [12], can be explained by the single AhR pathway. The molecular mechanism involved in the AhR-independent pathway(s) leading to TCDD-...
Ngày tải lên: 23/03/2014, 13:20
Báo cáo khoa học: A new pathway encompassing calpain 3 and its newly identified substrate cardiac ankyrin repeat protein is involved in the regulation of the nuclear factor-jB pathway in skeletal muscle pdf
... binding to titin by improving the accessibility of the titin-binding domain. Interestingly, the importance of CARP inter- action for its function was recently demonstrated in a Fig. 3. Calpain ... confirm this hypothesis. The results obtained in the present study strongly suggest that, once cleaved, CARP interaction with the region N2A is reinforced. CARP interacts with titin...
Ngày tải lên: 29/03/2014, 21:20
Hướng dẫn khắc phục lỗi “username is not in the sudoers file...” trong Ubuntu doc
... MUST be edited with the 'visudo' command as root. # # Please consider adding local content in /etc/sudoers.d/ instead of # directly modifying this file. # # See the man page for ... việc gì nữa, và thay vào đó hệ thống sẽ hiển thị thông báo lỗi như sau: damien is not in the sudoers file. This incident will be reported trong đó damien là tên tài khoản đang sử d...
Ngày tải lên: 30/03/2014, 00:20
Báo cáo khoa học: Myocyte enhancer factor 2B is involved in the inducible expression of NOX1⁄ NADPH oxidase, a vascular superoxide-producing enzyme ppt
... 3B). These findings clearly indicate that the MEF2-binding site between )139 and )130 is essential for PGF 2a -induced activation of the NOX1 promoter. Binding of MEF2 to the consensus sequence in the ... II-induced chronic hypertension using NOX1-deficient mice [19]. The basal level of the NOX1 transcript is much lower than the levels of other NOX isoforms expressed in va...
Ngày tải lên: 30/03/2014, 03:20
Báo cáo khoa học: The GxxxG motif of the transmembrane domain of subunit e is involved in the dimerization/oligomerization of the yeast ATP synthase complex in the mitochondrial membrane doc
... cerevisiae (P81449, Swiss-Prot) are in bold. The numbering of the yeast sub- unit e begins at the initiating methionine. The star indicates the position of the unique cys- teine residue of the ... alanine residue was inserted after Phe18 in order to disrupt a helix–helix packing interface involving the amino- acid residues on both sides of the insertion [40]. In the...
Ngày tải lên: 31/03/2014, 01:20