Báo cáo y học: " Helicobacter pylori induces mitochondrial DNA mutation and reactive oxygen species level in AGS cells"
... Paper Helicobacter pylori induces mitochondrial DNA mutation and reactive oxygen species level in AGS cells Xue-Wen Huang 1,* , Rui-Hua Luo 2,*, Qi Zhao 3, Zhong-Ze Shen 4, Li-Li Huang 1, Xian-Yuan ... Vacuolating cytotoxin in Helico-bacter pylori water-soluble proteins upregulates chemokine expression in human eosinophils via Ca2+ influx, mitochondrial rea...
Ngày tải lên: 25/10/2012, 11:18
... characterization of the single-stranded DNA (ssDNA) binding protein from H. pylori. The N-ter- minal DNA binding domain shows significant homology with E. coli single-stranded DNA binding protein (SSB), whereas ... (1987) Investigation of the role of individual tryptophan residues in the binding of Escherichia coli single-stranded DNA binding protein to single-stranded polynucleotid...
Ngày tải lên: 30/03/2014, 02:20
... utilizes the synthetic tri-peptide substrate N-[3-(2-furyl)acryloyl]-- phenylalanylglcylglcine (FAPGG). FAPGG is hydro-lyzed by ACE to furylacryloylphenylalanine (FAP) and glycylglycine. Hydrolysis of ... activity of the renin-angiotensin system (RAS), decreased insulin sensitivity, and inflammation in an in vivo laboratory model. Design and Method: We divided forty mature, female S...
Ngày tải lên: 26/10/2012, 08:57
Báo cáo Y học: Loss-of-function variants of the human melanocortin-1 receptor gene in melanoma cells define structural determinants of receptor function doc
... rate-limiting enzyme in melanin synthe- sis, tyrosinase, is increased and skin pigmentation is promoted. Melanin pigments are complex heteropolymers, which can be classified into two main groups: ... eumelanins, and the reddish to yellow, sulfur- containing phaeomelanins [17]. Although both types of melanins are found in different relative proportions in all skin types, the phaeomela...
Ngày tải lên: 17/03/2014, 10:20
Tài liệu Báo cáo khoa học: Helicobacter pylori acidic stress response factor HP1286 is a YceI homolog with new binding specificity pdf
... ligand and the protein). Another arginine, Arg153, is close to the open- ing of the cavity, but totally buried inside it. Its side chain forms five hydrogen bonds with main chain carbonyl oxygen ... which results in nonspecific release of the cyto- plasmic contents of the bacterium [10–12]. Keywords erucamide; fatty-acid binding proteins; Helicobacter pylori; lipid binding; lipocalins...
Ngày tải lên: 16/02/2014, 14:20
Báo cáo Y học: Functional integration of mitochondrial and hydrogenosomal ADP/ATP carriers in the Escherichia coli membrane reveals different biochemical characteristics for plants, mammals and anaerobic chytrids pdf
... significantly higher affinities for both, ADP and ATP. The corresponding K m values range between 10 and 22 l M . They are only slightly in uenced by CCCP. On the other hand, the kinetic data of the hydrogenosomal ... The radioactively labeled nucleotides, which were released after preloading, were analyzed by thin-layer (poly(ethylene amine) chro- matography. To investigate to what degree...
Ngày tải lên: 18/03/2014, 01:20
Báo cáo Y học: CTGF/Hcs24 induces chondrocyte differentiation through a p38 mitogen-activated protein kinase (p38MAPK), and proliferation through a p44/42 MAPK/extracellular-signal regulated kinase (ERK) doc
... We investigated the effects of MAP kinase inhibitors on pathways of proliferation by analyzing DNA synthesis, and pathways of differentiation by analyzing proteoglycan synthesis, in HCS-2/8 and ... MAP kinase inhibitors in both HCS-2/8 cells and RGC cells induced by CTGF/Hcs24. Previously, we reported that CTGF/Hcs24 induced DNA synthesis, and proteoglycan synthesis in HCS-2...
Ngày tải lên: 24/03/2014, 04:21
Báo cáo khoa học: Helicobacter pylori neutrophil-activating protein activates neutrophils by its C-terminal region even without dodecamer formation, which is a prerequisite for DNA protection – novel approaches against Helicobacter pylori inflammation ppt
... one. DNA- binding capacity determined by gel retardation assays and DNA protection against hydroxyl radicals The DNA- binding capacity of HP-NAP was assayed under several conditions, as described in ... neutrophils and monocytes, and it induces ROI production in humans by activating the plasma membrane NADPH oxidase via a signaling pathway involving trimeric G-protein, phospha...
Ngày tải lên: 30/03/2014, 04:20
Báo cáo Y học: Expression of glucose transporter-2, glucokinase and mitochondrial glycerolphosphate dehydrogenase in pancreatic islets during rat ontogenesis potx
... secretion of insulin. Bearing this in mind, we determined the activities of citrate synthase (an enzyme of the Krebs cycle re¯ecting the number of mitochondria [10]), succi- nate dehydrogenase and cytochrome ... generously donated by B. Thorens, Lausanne, Switzerland, using the DIG RNA labelling kit (Boehringer-Mannheim, Germany). CDNA synthesis, PCR ampli®cations, and Southern-blot ana...
Ngày tải lên: 31/03/2014, 15:20
Báo cáo y học: "Oral Rehydration Therapy for Preoperative Fluid and Electrolyte Management"
... fluid and electrolyte management is usually performed by intravenous therapy. We investigated the safety and effectiveness of oral rehydration therapy (ORT) for preoperative fluid and electrolyte ... patients are inevitably exposed to dry month and hunger. In Japan, pre-operative fluid and electrolyte management is usually performed by intravenous therapy, and the fasting time p...
Ngày tải lên: 25/10/2012, 10:51