... Open AccessAvailable online http://ccforum.com/content/9/4/R303R303Vol 9 No 4ResearchCircadian pattern of activation of the medical emergency team in a teaching hospitalDaryl Jones1, Samantha Bates2, ... hospital loudspeakers and paging system, and adetailed log of all calls is maintained.Criteria for medical emergency team activationCalling criteria for our MET...
... water
ad libitum. Rat care, handling and all the experimental
procedures were in accordance with internationally accep-
ted principles concerning the care and use of laboratory
animals. The rats ... cell surface [32]. Thus, the potential activation
of a membrane-associated neutral sphingomyelinase by
apoptosis inducers would generate Cers that initiate a
cascade of event...
... 4E).
These results indicate that activation of MIG-17
occurred in the basement membranes of the muscle,
intestine and gonad in the L3 larvae.
We next studied the activation of MIG-17 in adult
animals ... larvae
(Fig. 5A, B). Although Monoclonal 2 recognized the
gonadal basement membrane, the staining of intestinal
and muscular basement membranes was often faint
a...
... PA, USA.
Diane Litman, Johanna Moore, Myroslava Dzikovska,
and Elaine Farrow. 2009. Using natural lan-
guage processing to analyze tutorial dialogue cor-
pora across domains and modalities. In ... Makatchev, and Umarani
Pappuswamy. 2006. Understanding complex nat-
ural language explanations in tutorial applications.
In Proceedings of the Third Workshop on Scalable
Natural Language U...
... Kammen RA & Collard JG (1997)
Targeting of Tiam1 to the plasma membrane requires
the cooperative function of the N-terminal pleckstrin
homology domain and an adjacent protein interaction
domain. ... promoter activation
was strongly inhibited by selective inactivation of the
AP-1 site and completely inhibited by simultaneous
inactivation of the AP-1 and PEA-3 ⁄ ETS-1 si...
... nuclear factor kappaB
activity and are independent of the B-Raf ⁄ mitogen-acti-
vated ⁄ extracellular signal-regulated protein kinase path-
way and the Akt pathway. Cancer 104, 879–890.
26 Takada ... further investigated whether the activation of
ERK1 ⁄ 2 and p38 MAPK may be part of the antipro-
liferative activity of ATP, as these kinases are import-
ant regulators of pro...
... appears as a 15-kDa band, containing both the
N- and C-terminal chains that are identical in size (band A) .
Activation of double-chain trypsinogen to double-chain
trypsin results in the appearance ... beginning of the incubation.
SDS/PAGE analysis of trypsinogens
Autoactivation and degradation of trypsinogens was also
visualized by gel electrophoresis and staining. Typ...
... comparing
data obtained from different studies.
Mast-cell activation pathways
The signaling pathways that regulate the activation of
mast cells upon FceRI cross-linking have been investi-
gated in ... complex leads also to activation of
the mitogen-activated protein kinase (MAPK) path-
ways. Ca
2+
mobilization and MAPK activation lead to
the activation of downstream...
... enzymatic and chemical clea-
vage; human acid sphingomyelinase; MALDI-MS; PSD.
Human acid sphingomyelinase (haSMase, EC 3.1.4.12) is a
lysosomal enzyme catalyzing the degradation of sphingo-
myelin ... mmolÆmg
)1
Æh
)1
in a detergent
containing assay system [2]. The sequence of mature
bc-haSMase contains 23 additional N-terminal amino acid
residues compared to the sequence of...
... binding data were analyzed either by
nonlinear regression analysis or by the method of Scat-
chard. Nonlinear regression analysis of data from indi-
vidual binding curves indicated that the data were
described ... were also analyzed according to the Scatchard method
[47]. Linear regression analyses of binding data gave dissoci-
ation constants (K
d
), calculated from the recipro...