Báo cáo khoa học: "Impact of computerized physician order entry on medication prescription errors in the intensive care unit: a controlled cross-sectional trial"

Tài liệu Báo cáo khoa học: Distribution of class I, III and IV alcohol dehydrogenase mRNAs in the adult rat, mouse and human brain ppt

... IV,exon 7Human CCT CCA AAG ACA CAT CCC TTC CAT GTG CGT CCA GTG AAG AGC AAC ATC GGhADH4-2 ADH class IV,exon 6Human AGC CCA TGA TGA CTG ACA GGC CAA CTC CTC CCA GGC CAA AGA CGA CGC A hADH4-3 ADH ... TGG ATC TCA AAA TGT CAG GAC AGT CCGrADH4-2 ADH class IV,exon 7Rat CAT CAT CTC TGC TCT TCC AAC CAC CAA AGA CGC AGC CCT TCC ATG TCC GmADH1 ADH class I,exon 6Mouse TAC AGC CAA TGA TGA CAG ACA ... species.Discussion The distribution of ADHs in the brain is of particularinterest because of their implications in the metabolism of ethanol and retinoic acid. In vitro and in vivo data indicatethat ADH1,...

Báo cáo khoa học: Existence of novel b-1,2 linkage-containing side chain in the mannan of Candida lusitaniae, antigenically related to Candida albicans serotype A potx

... h,LM4;,LM5;j,LM6;s,Manb1ﬁ2Mana1ﬁ2Mana1ﬁ2Mana1ﬁ2Man; d,Manb1ﬁ2Manb1ﬁ2Mana1ﬁ2Man a1 ﬁ2Mana1ﬁ2Man; n,Manb1ﬁ2Mana1ﬁ3Mana1ﬁ2Mana1ﬁ2Man; m,Manb1ﬁ2Manb1ﬁ2Mana1ﬁ3Mana1ﬁ2Mana1ﬁ2Man.2572 N. Shibata et al. (Eur. ... andManb1ﬁ2Manb1ﬁ2Mana1ﬁ3Mana1ﬁ2Mana1ﬁ2Manwere prepared from the mannan of C. guilliermondii [17]or C. saitoana [35] and Manb1ﬁ2Mana1ﬁ2Mana1ﬁ2Mana1ﬁ2Man and Manb1ﬁ2Manb1ﬁ2Mana1ﬁ2Mana1ﬁ2Mana1ﬁ2Man ... 4.017 a1 ﬁ6Mana1ﬁ6Mana1ﬁ6Mana1ﬁ6›2Mana111 5.104 4.029 a1 ﬁ6Mana1ﬁ6Mana1ﬁ6Mana1ﬁ6›2 ›2 ›2Mana112 5.093 3.997 a1 ﬁ6Mana1ﬁ6Mana1ﬁ6Mana1ﬁ6›2 a1 ﬁ2Mana118.913 5.074 4.008 a1 ﬁ6Mana1ﬁ6Mana1ﬁ6Mana1ﬁ6›2...

Tài liệu Báo cáo khoa học: Impact of the native-state stability of human lysozyme variants on protein secretion by Pichia pastoris doc

... additional vari-ants studied here have single amino acid substitutions in the b-domain or near the a ⁄ b-domain interface asshown in Fig. 1. The thermal denaturation behaviour of these mutants was ... extent. Of particular interest from the point of view of amy-loid disease is the characterization of the two newmutational variants associated with clinical disease.Analysis of both the F57I and ... protein and the thermo-stability of the native state of the protein (Fig. 2A) .This correlation shows that even small changes in the protein native stability can have a dramatic effect on the amount...

Báo cáo khoa học: Impact of cyclic hypoxia on HIF-1a regulation in endothelial cells – new insights for anti-tumor treatments doc

... O2consumption) and the concomitant activation of Aktconcur to support the accumulation of HIF- 1a duringCyH. Of note, in the immunoblotting data correspondingto the various hypoxic and reoxygenation phases, ... indicates that the stim-ulatory effect of CyH on HIF- 1a was dampened byeNOS activation ⁄ phosphorylation. Furthermore, the failure of the NOS inhibitor to maintain the induction of HIF- 1a in the ... observations also indicate the potential of combining Akt-targeting drugs with anti-angiogenic drugs, in particularthose interfering with the NO pathway.AbbreviationsAkt, protein kinase B;...

Báo cáo khoa học: "Impact of Initiative on Collaborative Problem Solving ∗" docx

... get a sense of whether initiative may indeed affect learning in thiscontext by automatically tagging for initiative usingan approximation of Walker and Whittaker’s utter-ance based allocation ... for analysis.4. Drawing area: Here users can diagram datastructures to aid in the explanation of parts of the problem being solved. The drawing areahas objects representing nodes and links. Theseobjects ... Since the goals of our problems areunderstanding and potentially correcting a program,actions in our domain that show task initiative in- clude actions such as explaining what a section of code...

Tài liệu Báo cáo khoa học: Mechanisms of amyloid ﬁbril formation – focus on domain-swapping doc

... modulation of screening by changing the local environment and inter-and ⁄ or intramolecular interactions may have a signiﬁ-cant in uence on the preferential conformations of a single amino acid ... whereas, for most of the other cases, the original publications are cited. On the basis of our research on cystatins, which are capable of domain-swapping, and on a literature survey of a number of ... network of hydrogen bonds between the main-chain amides and the polar side chains. The glu-tamine- and asparagine-rich regions are commonlyfound in the N-termini of both mammalian and yeastprion...

Tài liệu Báo cáo khoa học: ¨ Induction of Kruppel-like factor 4 by high-density lipoproteins promotes the expression of scavenger receptor class B type I pptx

... under in ammatory states, and implicat-ing KLF4 as a regulator of endothelial activation in response to proinﬂammatory stimuli [2]. Overexpres-sion of KLF4 in J77 4a macrophages induced the mac-rophage ... transforminggrowth factor-b1 and Smad3 signalling, implicatingKLF4 as a regulator of key signalling pathways thatcontrol macrophage activation [3]. Furthermore, it hasalso been demonstrated ... whereasexpression of KLF4 is decreased in intestinal adeno-mas of multiple intestinal neoplasia mice and in colo-nic adenomas of familial adenomatous polyposispatients. In this investigation, we ﬁrst...

Tài liệu Báo cáo khoa học: Phosphorylation of cyclin dependent kinase 4 on tyrosine 17 is mediated by Src family kinases pptx

... with the forward primer: 3¢-GTCACAGAGCCACAGTTCCAGCCAGGA-5¢. Codon 305 of C-YES was mutated fromAAA (Lys) to AGA (Arg) with the forward primer: 3¢-GGAACCACGAAAGTAG CAATC AGA ACACTA AAACC A GGTACAATGATGC-5 ... were assayed for Y17 kinase activity using the 96-wellplate format assay. Each sample contained 2.5 lg of total protein.Values are the average of four samples with error bars indicating the ... plate and tubeassays. The accumulation of C-YES in the precipitatescorrelated with the appearance of kinase activity in those samples. The level of depletion of kinase activitymirrored the...

Tài liệu Báo cáo khoa học: Dimers of light-harvesting complex 2 from Rhodobacter sphaeroides characterized in reconstituted 2D crystals with atomic force microscopy docx

... ultrasoft tapping-mode AFM was applied in combination with the choice of appropriate buffer forelectrostatic balancing of the AFM tip and the substrate. Electrostatically balanced tapping-modeAFM ... a less packed conﬁguration, indicating thatdense packing may induce the speciﬁc interactionsleading to zig-zagging LH2’s. The intermediate density of the dimer lattice, on the other hand, indicates ... The Netherlands2 State Key Lab of Microbial Technology, Shandong University, Jinan, ChinaPhotosynthetic bacteria use a large part of their internalvolume for functionalized invaginations of...

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