Characterization and targeting of cancer stem cells in gastric adenocarcinoma (LV thạc sĩ)

... generated Indeed, only ICM-like cell clusters were obtained for further analysis Refinement and increased efficiency of these two ESC protocols brings the potential to offer a reliable supply of embryonic ... trophoblastic cells in blastocysts derived from porcine 4- and 8cell embryos and isolated blastomeres cultured in vitro in the presence or absence of pr...

Ngày tải lên: 13/08/2014, 23:20

... al.: Characterization and targeting of phosphatidylinositol-3 kinase (PI3K) and mammalian target of rapamycin (mTOR) in renal cell cancer Journal of Translational Medicine 2011 9:133 Submit your ... factor; mTOR: Mammalian target of Rapamycin; PI3K: phospahtidylinositol-3 kinase; RCC: renal cell carcinoma; RTK: receptor tyrosine kinase; and T...

Ngày tải lên: 18/06/2014, 22:20

... Elfiky et al.: Characterization and targeting of phosphatidylinositol-3 kinase (PI3K) and mammalian target of rapamycin (mTOR) in renal cell cancer Journal of Translational Medicine 2011 9:133 ... factor; mTOR: Mammalian target of Rapamycin; PI3K: phospahtidylinositol-3 kinase; RCC: renal cell carcinoma; RTK: receptor tyrosine kinase; and T...

Ngày tải lên: 20/06/2014, 04:20

... within a small number of cells in monolayer culture Following injection into NP tissue explants, MSCs stained strongly positive for type II collagen and matrix staining in the vicinity of the injected ... viability/metabolic activity of injected mesenchymal stem cells Photomicrographs representative of caspase immunopositivity and polyAcells mRNA staining in...

Ngày tải lên: 09/08/2014, 01:22

... of potential markers for cancer stem cells in large cell neuroendocrine carcinoma of the lung An FFPE proteomic study Journal of Clinical Bioinformatics 2011 1:23 Submit your next manuscript to ... upon Tyne, U.K.), polyclonal rabbit anti CGA antibody (DAKO Japan, Kyoto, Japan) and monoclonal mouse anti SYN antibody (DAKO Japan, Kyoto, Japan) The staining...

Ngày tải lên: 10/08/2014, 09:22

... of publications • Tham M, Ramasamy S, Gan H, Ramachandran A, Poonepalli A, Yu YH, Ahmed S Chondroitin sulfate proteoglycan stimulates neural stem cell survival via EGFR signalling pathways Manuscript ... quiescent and only become activated at the start of each hair cycle In addition, they are activated during tissue damage and participate in wound healing (Blanpain...

Ngày tải lên: 12/09/2015, 21:26

... Komarova et al Journal of Ovarian Research 2010, 3:12 http://www.ovarianresearch.com/content/3/1/12 a means to track malignant tissues or for the delivery of anticancer agents to tumors [2,5-9] Several ... relevance of our strategy in an ovarian tumor model, and showed that the number of modified MSC carriers increased in intraperitoneal tumors Artificial receptor stra...

Ngày tải lên: 20/06/2014, 07:20

... of MSCs to cancer cells, nature of tumour cells and cancer stem cells, integrity of immune system, number of stem cell passages and site of injection; all can affect the outcome of MSCs use in ... tissues by assessing the gene expression profile of some of the Wnt signaling target genes:cyclin D, PCNA, survivin, b-catenin Methods Ninety albino female rats inbred st...

Ngày tải lên: 10/08/2014, 10:21

... this inflammatory and catabolic cascade and demonstrated that curcumin (6) has the capacity to block the action of pro-inflammatory cytokines in the joint thus disrupting the inflammatory cycle inhibit ... intestinal absorption of curcumin is fairly low, mainly due to the fact that curcumin is practically insoluble in water, and that it has a low bio-availability [44,45] Despi...

Ngày tải lên: 12/08/2014, 14:22

... SJ: Applying the principles of stem -cell biology to cancer Nat Rev Cancer 2003, 3:895-902 17 Campbell LL, Polyak K: Breast tumor heterogeneity: cancer stem cells or clonal evolution? Cell Cycle ... only in a subset of the cancer cells (the stem cells) we can see that for any size of tumour, because of the much smaller number of stem cells, clonal evolution is pre...

Ngày tải lên: 13/08/2014, 16:20

... endothelial progenitor cells during progression of multiple organ dysfunction syndromes The (top) migratory syndromes capacities and (bottom) adhesive capacities of endothelial progenitor cells in (left) ... receptor-2 Endothelial progenitor cells were incubated with 1,1-dioctadecyl-3,3,3,3-tetramethylindocarbocyanine-labeled acetylated low-density lipoprotei...

Ngày tải lên: 13/08/2014, 18:22

... against the allergic airway inflammation depends on the modulation of spleen dendritic cell function and induction of regulatory T cells in mice Genetic Vaccines and Therapy 2010, 8:2 Page of ... and mature DCs, resulting in tolerogenic interaction with T cells in SIT We found that the combination of DNA vaccination with Fc and OVA...

Ngày tải lên: 14/08/2014, 19:22

... kinase domain is located in the intracellular part of the protein and is responsible for phosphorylating specific tyrosine residues of nearby proteins, including the intracellular domains of the ... List of Tables List of Tables Table No Title of Table Page Summary information on transgenic lines characterized in the 56 present study Summary of characterization of o...

Ngày tải lên: 03/10/2015, 11:42

... as the basis for concluding that NK cells play no role in innate resistance to HSV-1 Likewise, we question the validity of comparisons of HSV-1 infection in mice that exhibit "high" or "low" natural ... NK cells are dispensable for the innate resistance of mice to HSV-1 infection, further investigation is necessary to determine what role, if any, NK cel...

Ngày tải lên: 19/06/2014, 08:20

... NK cells are dispensable for the innate resistance of mice to HSV-1 infection, further investigation is necessary to determine what role, if any, NK cells play in human resistance to HSV-1 infection ... NK cells and/or professional APCs confer innate resistance to HSV-1 infection via the secretion of IFN-γ at early times p.i The following study was initiat...

Ngày tải lên: 20/06/2014, 04:20