... Takayama T, Kato J, Yamauchi N, Kogawa K, Sakamaki S, Hirayama Y, Kohda K, Niitsu Y Involvement of transforming growth factor-beta and thrombopoietin in the pathogenesis of myelodysplastic syndrome ... S, Vainchenker W, Wendling F Prominent role of TGF-beta in thrombopoietin-induced myelofibrosis in mice Blood 2002;100:3495-503 32 Erusalimsky JD, Franklin R and Hong Y Is the platelet lowering ... that serum levels of TPO, the major cytokine involved in the regulation of megakaryocyte and platelet growth and release, was raised at six months of anagrelide treatment; concomitantly there was...