Atlas of dermatology in internal medicine

... matter_FINAL.qxd 5/25/04 8:09 AM Page vii PREFACE Mayo Clinic Images in Internal Medicine: Self-Assessment for Board Exam Review was begun in 1998 as an adjunct to a presentation for the Mayo Internal ... that Mayo Clinic Images in Internal Medicine: Self-Assessment for Board Exam Review will be an aid for preparation for board examina...

Ngày tải lên: 16/02/2014, 18:20

... though they may be seeing other specialists The internist has an important role in educating patients about the indications, benefits, risks, and limitations of genetic testing in the management of ... also influence the severity of infirmity, effect of treatment, and progression of disease The primary care clinician is now faced with the role of recognizing and co...

Ngày tải lên: 07/07/2014, 01:20

... the relative risk ranges from two- to fivefold, underscoring the importance of family history for these prevalent disorders Pending further advances in genetic testing, the key to assessing the ... individual will vary depending on the size of the pedigree, the number of unaffected relatives, and the types of diagnoses, as well as the ages of disease onset within...

Ngày tải lên: 07/07/2014, 01:20

... cancer, representing another confounding variable in the pedigree analysis Some of the aforementioned features of the family history are illustrated in Fig 64-1 In this example, the proband, a ... whether based on family history, characteristic physical findings, or biochemical testing Careful clinical assessment can define the phenotype, thereby preventing unnecessary t...

Ngày tải lên: 07/07/2014, 01:20

... established disease, genetic testing for susceptibility to chronic disease is being increasingly integrated into the practice of medicine In most cases, however, the discovery of disease-associated genes ... analysis of the gene of interest In addition, PCR enables genetic testing on minimal amounts of DNA extracted from a wide range of tissue sources including leuko...

Ngày tải lên: 07/07/2014, 01:20

... of their personal likelihood of disease in preparing pretest educational strategies Often, patients harbor unwarranted fear or denial of their likelihood of genetic risk Genetic testing has the ... concern that testing during childhood violates a child's right to make an informed decision regarding testing upon reaching adulthood On the other hand, testing should be offered in...

Ngày tải lên: 07/07/2014, 01:20

... issues; Assist in determining the role of genetic testing for the individual and family; Ensure that the patient is aware of the indications, process, risks, benefits, and limitations of the various ... prevention Finally, patients should understand the natural history of the disease as well as the potential options for intervention, including screening, prevention,...

Ngày tải lên: 07/07/2014, 01:20

... based testing for presymptomatic diagnosis of the disorder However, up to onethird of individuals who are homozygous for the HFE mutation not have evidence of iron overload Consequently, in the absence ... assessment of phenotypic expression awaits further studies In contrast to the issue of population screening, it is important to test and counsel other family members w...

Ngày tải lên: 07/07/2014, 01:20

... intensive clinical screening, as it remains very challenging to predict disease penetrance, expression, or clinical course Although genetic diagnosis of these and other disorders is only beginning ... used in the clinical setting, predictive testing holds the promise of allowing earlier and more targeted interventions that can reduce morbidity and mortality We can expect the...

Ngày tải lên: 07/07/2014, 01:20

... to Chinese researchers as most of them are developed in English [18] In this study, we aim to assess the validity, responsiveness and minimally important change of a Chinese version of MYMOP, in ... quality of life measures J Eval Clin Pract 2000, 6(1):39-49 doi:10.1186/1477-7525-8-111 Cite this article as: Chung et al.: Using Chinese Version of MYMOP...

Ngày tải lên: 12/08/2014, 01:21

... analyses for the two specialties (family medicine and internal medicine) separately and combined We conducted regression analyses in order to identify factors that are associated with the characteristics ... conception and design: EAA, RM, MCW, AM, and HJS; acquisition of data: EAA, RM, AS, MCW, AM, and TR; analysis and interpretation of data: EAA, GHG, and H...

Ngày tải lên: 11/08/2014, 05:21