Atlas of dermatology in internal medicine
Tài liệu Mayo Clinic Images in Internal Medicine: Self-Assessment for Board Exam Review docx
... matter_FINAL.qxd 5/25/04 8:09 AM Page vii PREFACE Mayo Clinic Images in Internal Medicine: Self-Assessment for Board Exam Review was begun in 1998 as an adjunct to a presentation for the Mayo Internal ... that Mayo Clinic Images in Internal Medicine: Self-Assessment for Board Exam Review will be an aid for preparation for board examination certification or recertification and medical clerkship review ... detailed reference index, and specialty chain referencing, Mayo Clinic Images in Internal Medicine: Self-Assessment for Board Exam Review is really three effective learning texts bound in one cover...
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Chapter 064. The Practice of Genetics in Clinical Medicine (Part 1) pptx
... though they may be seeing other specialists The internist has an important role in educating patients about the indications, benefits, risks, and limitations of genetic testing in the management of ... also influence the severity of infirmity, effect of treatment, and progression of disease The primary care clinician is now faced with the role of recognizing and counseling patients ... in monozygotic twins ranges between 50 and 90% Diabetes or impaired glucose tolerance occurs in 40% of siblings and in 30% of the offspring of an affected individual Despite the fact that diabetes...
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Chapter 064. The Practice of Genetics in Clinical Medicine (Part 2) pptx
... the relative risk ranges from two- to fivefold, underscoring the importance of family history for these prevalent disorders Pending further advances in genetic testing, the key to assessing the ... individual will vary depending on the size of the pedigree, the number of unaffected relatives, and the types of diagnoses, as well as the ages of disease onset within the family For example, a ... disease-causing mutations are more prevalent in certain ethnic groups For instance, >2% of the Ashkenazi population carry one of three specific mutations in the BRCA1 or BRCA2 genes The prevalence of the...
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Chapter 064. The Practice of Genetics in Clinical Medicine (Part 3) potx
... cancer, representing another confounding variable in the pedigree analysis Some of the aforementioned features of the family history are illustrated in Fig 64-1 In this example, the proband, a ... whether based on family history, characteristic physical findings, or biochemical testing Careful clinical assessment can define the phenotype, thereby preventing unnecessary testing and directing ... found, then it is possible to test for this particular alteration in the proband and other family members, if they so desire In the example shown, if the proband's father has the BRCA1 mutation, there...
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Chapter 064. The Practice of Genetics in Clinical Medicine (Part 4) potx
... established disease, genetic testing for susceptibility to chronic disease is being increasingly integrated into the practice of medicine In most cases, however, the discovery of disease-associated genes ... analysis of the gene of interest In addition, PCR enables genetic testing on minimal amounts of DNA extracted from a wide range of tissue sources including leukocytes, fibroblasts, epithelial cells in ... provided informed consent In the majority of cases, genetic testing should be offered only to individuals with a suggestive personal or family medical history or in the context of a clinical trial...
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Chapter 064. The Practice of Genetics in Clinical Medicine (Part 5) pptx
... of their personal likelihood of disease in preparing pretest educational strategies Often, patients harbor unwarranted fear or denial of their likelihood of genetic risk Genetic testing has the ... concern that testing during childhood violates a child's right to make an informed decision regarding testing upon reaching adulthood On the other hand, testing should be offered in childhood for disorders ... early in childhood, and the issue of prophylactic thyroidectomy should be addressed with the parents of children with documented mutations (Chap 3 45) Informed Consent When the issue of testing...
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Chapter 064. The Practice of Genetics in Clinical Medicine (Part 6) pot
... issues; Assist in determining the role of genetic testing for the individual and family; Ensure that the patient is aware of the indications, process, risks, benefits, and limitations of the various ... prevention Finally, patients should understand the natural history of the disease as well as the potential options for intervention, including screening, prevention, and in certain circumstances— ... understanding of these genetic diseases and as more is learned about the functions of the gene products involved Individuals who test negative for a mutation in a disease-associated gene identified in...
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Chapter 064. The Practice of Genetics in Clinical Medicine (Part 7) pdf
... based testing for presymptomatic diagnosis of the disorder However, up to onethird of individuals who are homozygous for the HFE mutation not have evidence of iron overload Consequently, in the absence ... assessment of phenotypic expression awaits further studies In contrast to the issue of population screening, it is important to test and counsel other family members when the diagnosis of hemochromatosis ... in the absence of a positive family history, current recommendations include phenotypic screening for evidence of iron overload followed by genetic testing Whether genetic screening for hemochromatosis...
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Chapter 064. The Practice of Genetics in Clinical Medicine (Part 8) pot
... intensive clinical screening, as it remains very challenging to predict disease penetrance, expression, or clinical course Although genetic diagnosis of these and other disorders is only beginning ... used in the clinical setting, predictive testing holds the promise of allowing earlier and more targeted interventions that can reduce morbidity and mortality We can expect the availability of ... distinct genetic abnormalities by the time they acquire invasive or metastatic potential (Chaps 79 and 80) Consequently, the major impact of genetic testing in these cases is to allow more intensive...
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báo cáo khoa học:" Using Chinese Version of MYMOP in Chinese Medicine Evaluation: Validity, Responsiveness and Minimally Important Change" ppt
... to Chinese researchers as most of them are developed in English [18] In this study, we aim to assess the validity, responsiveness and minimally important change of a Chinese version of MYMOP, in ... quality of life measures J Eval Clin Pract 2000, 6(1):39-49 doi:10.1186/1477-7525-8-111 Cite this article as: Chung et al.: Using Chinese Version of MYMOP in Chinese Medicine Evaluation: Validity, Responsiveness ... effect of such changes on the results Page of Conclusions A Chinese version of MYMOP is developed using standard cultural adaptation methodology In a CM clinical setting, CMYMOP is a valid and responsive...
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Báo cáo y học: "Curricula for teaching the content of clinical practice guidelines to family medicine and internal medicine residents in the US: a survey study" ppt
... analyses for the two specialties (family medicine and internal medicine) separately and combined We conducted regression analyses in order to identify factors that are associated with the characteristics ... conception and design: EAA, RM, MCW, AM, and HJS; acquisition of data: EAA, RM, AS, MCW, AM, and TR; analysis and interpretation of data: EAA, GHG, and HJS; drafting of manuscript: EAA; critical revision ... Vedavalli A, Schunemann HJ, Akl EA, Mustafa R, Slomka T, Alawneh A, et al.: An educational game for teaching clinical practice guidelines to Internal Medicine residents: development, feasibility...
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