... the widespread application of nanodelivery systems in medicine Design of nanotechnology – based drug delivery Systems Nanoparticles can be used in targeted drug delivery at the site of disease ... the uptake of poorly soluble drugs [8,9], the targeting of drugs to a specific site, and drug bioavailability A schematic comparison of untargeted and targeted drug delivery systems is...
Ngày tải lên: 20/06/2014, 00:20
... article as: He et al.: Ultrasound microbubble-mediated delivery of the siRNAs targeting MDR1 reduces drug resistance of yolk sac carcinoma L2 cells Journal of Experimental & Clinical Cancer Research ... attack of anti-cancer drugs [35-37] In this study, we investigated whether the downregulation of MDR1 could enhance the drug sensitivity of yolk...
Ngày tải lên: 10/08/2014, 10:21
Tài liệu Báo cáo khoa học: "Humor as Circuits in Semantic Networks" doc
... pathway scoring for calculating semantic similarity in conceptnet In Proceedings of the Ninth International Conference on Computational Semantics, pages 385– 389 Association for Computational Linguistics ... visualizing opinions and sentiments in a multi-dimensional vector space Knowledge-Based and Intelligent Information and Engineering Systems, pages 385–393 E Cambria, R Speer, C Ha...
Ngày tải lên: 19/02/2014, 19:20
Tài liệu Báo cáo khoa học: "Lemmatisation as a Tagging Task" pdf
... the task of lemmatisation as a category tagging task and using an efficient tagger to perform it results in a performance that is at the state-of-the-art level The adaptive general classification ... [pos1 ] Table 1: Feature sets Experimental Evaluation The advantage of structuring the lemmatisation task as a tagging task is that it allows us to apply successful tagging techniqu...
Ngày tải lên: 19/02/2014, 19:20
Tài liệu Báo cáo khoa học: "Wikipedia as Sense Inventory to Improve Diversity in Web Search Results" doc
... with actual data in our testbed Finally, in Section we discuss a few strategies to classify Web pages into word senses, and apply the best classifier to enhance diversity in search results The ... frequencies in (search results) Web pages is crucial to have a usable sense inventory Is it possible to estimate Web sense frequencies from currently available inform...
Ngày tải lên: 20/02/2014, 04:20
Tài liệu Báo cáo khoa học: "WSD as a Distributed Constraint Optimization Problem" pptx
... Speech and Natural Language, pages 233–237, Morristown, NJ, USA Association for Computational Linguistics Ravi Sinha and Rada Mihalcea 2007 Unsupervised graph-basedword sense disambiguation using ... of a word as its variable Each agent wi is associated with the variable swi The value assigned to this variable indicates the sense assigned by the algorithm A DCOP (Modi, 2003; Modi et al....
Ngày tải lên: 20/02/2014, 04:20
Tài liệu Báo cáo khoa học: "Interpretation as Abduction" potx
... criteria are what Thasard (1978) has called consilienceand simplicity.Roughly, simplicityis that p(A) should be as small as possible,and consilienceis that q(A) should be as big as possible W e want ... favored why assume Q when it is cheaper to assume PI and P~ Hwlq-w2 • I, least specific abduction is favored-why assume PI and P2 when it is cheaper to assume Q But in pis ^ P~s ~ Q if...
Ngày tải lên: 21/02/2014, 20:20
Tài liệu Báo cáo khoa học: "Translation as Weighted Deduction" pdf
... word of a phrase chosen for translation be within d words of the the last word of the most recently translated phrase (Figure 1).3 The effect of this strategy is that, up to the last word covered ... goal item of MDd (1) requires that the last word of the last phrase translated be within d words of the end of the source sentence d = and d = I) This has important ramifications for scientific ......
Ngày tải lên: 22/02/2014, 02:20
Báo cáo khoa học: Peroxiredoxins as cellular guardians in Sulfolobus solfataricus – characterization of Bcp1, Bcp3 and Bcp4 pot
... analysis of bcp1, bcp3 and bcp4 under oxidative stress The involvement of bcp1, bcp3 and bcp4 in oxidative stress was investigated by assessing mRNA levels following treatment of S solfataricus ... contrast, the Bcp3 sequence only shows one cysteine at position 42 in the N-terminal region Expression and purification of Bcp1, Bcp3 and Bcp4 bcp1, bcp3...
Ngày tải lên: 07/03/2014, 05:20
Báo cáo khoa học: Homoadenosylcobalamins as probes for exploring the active sites of coenzyme B12-dependent diol dehydratase and ethanolamine ammonia-lyase docx
... useful as probes for exploring the active sites of AdoCbl-dependent enzymes In this paper, we have investigated the coenzymic properties of these homologues for diol dehydratase and ethanolamine ammonia-lyase ... totally inactive as coenzyme for ribonucleotide reductase, and the latter inactive for diol dehydratase [27] The X-ray structure of...
Ngày tải lên: 07/03/2014, 21:20
Báo cáo khoa học: "Generation as Dependency Parsing" potx
... Topological Dependency Grammar These factors are exactly the same that make dependency parsing for free word order languages difficult, and it seems worthwhile to see whether optimized parsers for dependency ... We make the following simplifying assumptions First, we assume that the nodes of the elementary trees of G are not labelled with feature structures Next, we assume that whenever...
Ngày tải lên: 08/03/2014, 07:20
Báo cáo khoa học: "PARSING AS NATURAL DEDUCTION " pot
... (see figure 12) S "- * S S/S, S / S , S, S\S, S\S -"* S S / , S~ S\S, S\S "" + S s -, s s, s\s, s\s * s S "+ S Figure 11: Category with position features S, $ \ -'* S S "- *S S '"* S S We can now ... tree 275 On the basis of these augmented categories, the overall syntax tree can be built up together with the proof for a sequent As it has already been discussed above, a "lef...
Ngày tải lên: 08/03/2014, 18:20
Báo cáo khoa học: Actin as target for modification by bacterial protein toxins docx
... hydrolase activity Photox targets all actin isoforms and like other toxins it modifies Arg177 and does not accept polymerized actin as substrate [68] Actin as target for toxin modification Aeromonas ... Arg–ADP-ribose bond in actin, which was catalyzed by C2 toxin, was cleaved by hydroxylamine, this was not the case for the ADP-ribose bond to actin catalyzed by TccC...
Ngày tải lên: 14/03/2014, 22:20
Báo cáo khoa học: Peroxisomes as dynamic organelles: peroxisome abundance in yeast docx
... mature peroxisome (3) Peroxisome inheritance (involving Myo2, Inp2, Inp1, Pex3 and Pex19), in which peroxisomes are faithfully inherited into the newly formed bud (3a) and ⁄ or are retained in the ... Peroxisome abundance in yeast R Saraya et al Fig Hypothetical model of peroxisome abundance In wild-type yeast cells peroxisome numbers may be maintained by a balance...
Ngày tải lên: 15/03/2014, 23:20
Báo cáo khoa học: Peroxisomes as dynamic organelles: autophagic degradation pot
... Schliebs W & Erdmann R Peroxisomes as dynamic organelles: peroxisomal matrix protein import FEBS J 277, 3268–3278 Saraya R, Veenhuis M & van der Klei IJ Peroxisomes as dynamic organelles: peroxisome ... pexophagy The autophagic selectivity towards peroxisomes is assumed to be defined at the interface of peroxisomal Autophagic degradation of peroxisomes Fig Interaction...
Ngày tải lên: 15/03/2014, 23:20