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Sepsis septic shock in children 2017

Báo cáo y học:

Báo cáo y học: "Epidermal wound healing in severe sepsis and septic shock in humans" pptx

... used for studying the basic biology of epidermal wound healing and the healing of burn injuries as well as the effect of jaundice and diabetes on epidermal wound healing [8-11] In this model, ... study Standard definitions were used to define sepsis, severe sepsis, and septic shock [15] Exclusion criteria included age under 18, any bleeding disorder, immunosuppression therapy, surgery not ... were presented in part at the 28th International Symposium on Intensive Care and Emergency Medicine in Brussels in 2008 References Epidermal healing is delayed in patients with severe sepsis • Authors'...
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Báo cáo y học:

Báo cáo y học: " Near-infrared spectroscopy during stagnant ischemia estimates central venous oxygen saturation and mixed venous oxygen saturation discrepancy in patients with severe left heart failure and additional sepsis/septic shock" potx

... stagnant ischemia estimates central venous oxygen saturation and mixed venous oxygen saturation discrepancy in patients with severe left heart failure and additional sepsis/septic shock Critical ... ScvO2-SvO2 discrepancy is clinically important • The skeletal muscle StO2 deoxygenation rate estimates the ScvO2-SvO2 discrepancy in patients with severe left heart failure with additional severe ... 26:1356-1360 Martin C, Auffray JP, Badetti C, Perrin G, Papazian L, Gouin F: Monitoring of central venous oxygen saturation versus mixed venous oxygen saturation in critically ill patients Intensive...
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Báo cáo y học:

Báo cáo y học: "4G/5G polymorphism of PAI-1 gene is associated with multiple organ dysfunction and septic shock in pneumonia induced severe sepsis: prospective, observational, genetic study" doc

... The glycoprotein serine protease plasminogen activator inhibitor-1 (PAI-1) is a key element in the inhibition of fibrinolysis The primary role of PAI-1 in vivo is fast acting inhibition of tissue- ... shows genetic association between the 4G allele of 4G/5G polymorphism and the occurrence of MODS and septic shock in pneumonia sepsis Comparing the allele frequencies of PAI-1 4G/5G polymorphism of ... in evaluating the effect of PAI-1 4G/ 5G polymorphism on MODS, sepsis severity and mortality in a relatively homogeneous cohort of patients of the same ethnicity Moreover, this study is the first...
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Báo cáo y học:

Báo cáo y học: "Availability of critical care resources to treat patients with severe sepsis or septic shock in Africa: a self-reported, continent-wide survey of anaesthesia providers" ppt

... htm#africa] doi:10.1186/cc9410 Cite this article as: Baelani et al.: Availability of critical care resources to treat patients with severe sepsis or septic shock in Africa: a selfreported, continent-wide ... resource availability to treat sepsis in Africa, particularly in rural hospitals Recent studies from Uganda [17] and Zambia [16] reported a much lower availability of basic monitoring devices or equipment ... was considered the secondary survey goal Data processing and statistical analysis Questionnaires were manually entered into a centralized database After random cross-checking, the database was...
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Báo cáo y học:

Báo cáo y học: "Disseminated tuberculosis presenting with polymorphonuclear effusion and septic shock in an HIV-seropositive patient: a case report" pot

... OK analyzed and interpreted our patient data and was a major contributor in writing the manuscript EP analyzed the data and was involved in drafting the manuscript and revising it critically CH ... CH and JAL performed the autopsy and the histological examination of our patient's spleen and lungs, and contributed in writing the manuscript MN analyzed the data and was involved in drafting ... omentum, pancreas, adrenal glands, thoracic, abdominal and retroperitoneal lymph nodes, and bone marrow Histologically, the nodules corresponded to necrotizing granulomas, with very abundant polymorphonuclears...
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Báo cáo y học:

Báo cáo y học: "Septic shock in pregnancy due to pyogenic sacroiliitis: a case report" docx

... González-Gay MA, Garc a- Porrua C, Ibañez D, Garcia-País MJ: Osteoarticular complications of brucellosis in an Atlantic area of Spain J Rheumatol 1999, 26:141-145 González-Juanatey C, González-Gay MA, ... during pregnancy requires a degree of clinical suspicion and should be confirmed by imaging diagnostic methods Plain radiography may give normal images in early disease There may be blurring ... clinical presentation may delay diagnosis, especially when considering that lower back pain is a common symptom in pregnancy and postpartum The diagnosis of pyogenic A new MRI performed weeks later...
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Báo cáo khoa học:

Báo cáo khoa học: "Circulating immune parameters predicting the progression from hospital-acquired pneumonia to septic shock in surgical patients" doc

... B, Kox WJ, Spies CD: The value of immune modulating parameters in predicting the progression from peritonitis to septic shock Shock 2001, 15:95-100 36 Sander M, Irwin M, Sinha P, Naumann E, Kox ... systemic progression of HAP to septic shock with respect to the pattern of circulating cytokines in surgical patients The primary aim of this study was to investigate whether patients, within four ... performed using the Mann- At the 'diagnosis of pneumonia' , the clinical and laboratory findings did not significantly differ between the groups (Table 2) The time from admission to the ICU to the time...
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Báo cáo khoa học:

Báo cáo khoa học: "Can we predict septic shock in patients with hospital-acquired pneumonia" ppt

... to septic shock (86% of cases with 100% survival), whereas 47% of patients developing septic shock were infected with Gram-negative bacteria (survival 55%) Moreover, 12 patients (16%; five without ... pneumonia in all patients Competing interests So, can we predict deterioration of HAP to septic shock using biochemical means? Taking into account all of the considerations mentioned above, in their ... progressive radiographic infiltrate along with clinical findings suggesting infection, such as fever, purulent sputum, leucocytosis and decline in oxygenation The combination of these criteria...
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Bóa cáo y học:

Bóa cáo y học: "Arginine-vasopressin in catecholamine-refractory septic versus non-septic shock in extremely low birth weight infants with acute renal injury" potx

... hours in infants with sepsis versus 30 ± 16 hours in non -septic infants These differences are due to the early deaths of two twins with cardiogenic shock In all six infants, MAP substantially increased ... purposes) The mortality rate was 1/3 in infants with sepsis-induced catecholamine-refractory shock compared to 3/3 in non -septic shock infants Discussion As reported in previous studies in children and ... catecholamine-refractory shock, indicating that it is also efficacious in ELBW infants AVP may be a viable rescue therapy for ELBW infants in a refractory vasodilatatory state and acute renal injury when conventional...
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Báo cáo y học:

Báo cáo y học: " Renal haemodynamic, microcirculatory, metabolic and histopathological responses to peritonitis-induced septic shock in pigs" ppt

... only, without providing their relationship to microcirculatory, metabolic and histopathological responses Prompted by these facts, we dynamically assessed the pattern of renal haemodynamics in ... porcine model of progressive hyperdynamic sepsis induced by faecal peritonitis Furthermore, a potential link between renal haemodynamics and renal cortex microcirculatory, metabolic and histological ... sham-operated and peritonitisinduced pigs at baseline Systemic variables Haemodynamic and oxygen exchange parameters, inflammatory responses, oxidative and nitrosative stress, and other laboratory parameters...
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Báo cáo y học:

Báo cáo y học: "Targeting the ubiquitin proteasome pathway for the treatment of septic shock in patients" pps

... pathway Interestingly, many of the genes in these pathways are regulated by the proteasome [18] Therefore, combined with our results, this may also help explain why targeting one aspect of a signaling ... Subsequently, TRAF6 interacts with UBC13/UEV1A, a heterodimer that catalyzes the synthesis of polyubiquitin chains assembled through linkage of the carboxyl terminus of one ubiquitin molecule to an internal ... target for anti-NF-κB intervention than the IKK cascade for treatment of septic shock Clinically, our findings may help explain why Velcade has greater efficacy than the IKK inhibitor PS-1145 in...
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Báo cáo y học:

Báo cáo y học: "Surviving meningococcal septic shock in childhood: long-term overall outcome and the effect on health-related quality of life" ppt

... in the interpretation of the results and writing of the manuscript EMWJ assisted in the interpretation of the results and writing of the manuscript KFMJ initiated this study and assisted in the ... article as: Buysse et al., Surviving meningococcal septic shock in childhood: long-term overall outcome and the effect on health-related quality of life Critical Care 2010, 14:R124 Page of ... in interpretation of the results and critically read the manuscript; JAH critically read the manuscript and assisted in interpretation of the results WCJH performed the statistical analysis and...
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Báo cáo y học:

Báo cáo y học: "Pathophysiological aspects of hyperglycemia in children with meningococcal sepsis and septic shock: a prospective, observational cohort study" docx

... Hokken-Koelega AC: Adrenal insufficiency in meningococcal sepsis: bioavailable cortisol levels and impact of interleukin-6 levels and intubation with etomidate on adrenal function and mortality J Clin ... (greater than 150 mg/dL) on admission is seen in 33% of critically ill children with meningococcal disease • Pathophysiologically, both a hyperinsulinemic and a hypoinsulinemic response play a ... may contribute to the occurrence of hyperglycemia in critically ill children with meningococcal sepsis and septic shock Key messages • Hyperglycemia with a blood glucose level of greater than...
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Báo cáo sinh học:

Báo cáo sinh học: "Time-course of sFlt-1 and VEGF-A release in neutropenic patients with sepsis and septic shock: a prospective study" pptx

... expression of sFlt-1 and VEGF -A in patients with hematological malignancies and chemotherapy-related FN, to gain insights about both potential roles of sFlt-1 in patients with febrile neutropenia and sepsis, ... Serum sFlt-1 and VEGF -A levels in FN Serum sFlt-1 and VEGF -A levels in patients with FN Box plots representing serial concentrations of sFlt-1 and VEGF -A in patients with FN with non-complicated sepsis ... of these biomarkers obtained in a “real world” setting will be able to capture this increase in sFlt- 1and/ or VEGF -A levels of patients with a worse prognosis and accurately discriminate FN patients...
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