... of glycogen in the intact liver in vivo Second, during infusion of [1-1 3C ]glucose, label incorporation was observed not only into the C1 of glycogen but also the C6 , which can only occur by label ... a mechanism can lead to increases in labeling of glycogen C6 even in the presence of decreased activity of the indirect pathway, provided that the increase in glycolytic flux exceeded the decreased ... (A) The stack plot of 1 3C spectra acquired over 7.6 h after beginning at t ¼ (right scale), the infusion of [1-1 3C ]glucose 1 3C- label incorporation into hepatic glycogen was detected in the glycogen...