... Definition and characteristics of hyaluronan (hyaluronic acid) and hylans Definition Characteristics Hyaluronan (hyaluronic acid) or sodium hyaluronate Long, nonsulfated, straight chains of variable ... [92] HA, hyaluronan (hyaluronic acid); MW, molecular weight; OA, osteoarthritis; PMN, polymorphonuclear N/A Yes Yes Yes Yes Yes N/A N/A Yes Yes Yes N/A N/A Inhibited macrophage phagocytosis and cell ... In the synovium of HA-treated knees, the number and aggregation of synoviocytes decreased, and both treatments reduced the number of inflammatory cells, including macrophages, lymphocytes, and...