... the ligand specificity of family carbohydrate- binding modules J Biol Chem 275, 4113 7– 4114 2 30 Accelrys (1993) InsightII v 2.3.0 Accelrys, San Diego, CA Determinants of ligand specificity in CtCBM11 ... grouped into three subfamilies: ‘surface -binding CBMs (type A), ‘glycan-chain -binding CBMs (type B), and ‘small sugar -binding CBMs (type C) [5] Determinants of ligand specificity in CtCBM11 The ... the building block of the ligand having the strongest contact with the protein shows the most intense NMR signals, enabling mapping of the ligand s binding epitope Finally, and most importantly...