Homologous recombination and directed differentiation in medaka ES cells development of vector systems

... hypoxia and reoxygenation have been reported to induce DNA damage [30–32], we examined the effects of pyruvate addition during hypoxia and after reoxygenation on DNA damage HepG2 cells were incubated ... by Singh et al [48], using alkaline electrophoresis, which allows detection of single-strand and double-strand breaks Pyruvate reduces DNA damage during...

Ngày tải lên: 18/02/2014, 16:20

... preponderant role of p38 in the regulation of gene expression at the level of mRNA stability The p38 MAP kinase is now known to stabilize a wide range of mRNAs including those encoding TNF-a, interferon ... organization of the actin cytoskeleton and the superinduction of the CTGF/ CCN2 gene Rho-like GTPases play a pivotal role in orchestrating changes...

Ngày tải lên: 19/02/2014, 16:20

... dimerization of cystatin F could be a process regulating its inhibitory properties Screening of proteases for their inhibition showed that cystatin F is different from other cystatins, both in terms of ... mutants of cystatin C have been prepared yet to study the effect of incorporating the FEBS Journal 272 (2005) 15351545 ê 2005 FEBS T Langerholc et al Cystatin...

Ngày tải lên: 19/02/2014, 17:20

... development by the project manager through ecollaboration Project management process All projects have a beginning and an ending, and project management has corresponding initiating and closing ... facilitate the progression to reduce time and cost in developing new products in SMEs To understand the importance of coordinating these sections with the...

Ngày tải lên: 07/03/2014, 00:20

... residing in both the inner and outer mitochondrial membrane, that is activated by mitochondrial Ca2+ overloading and other factors including oxidative stress [88,89] In neurons the presence of PTP in ... buffer the incoming calcium resulting in an abrupt, sustained and irreversible increase in [Ca2+]c, probably coincides with the cleavage of the exchanger (but see [1...

Ngày tải lên: 07/03/2014, 12:20

... from the liver of yellowtail, and found that the one-sided accumulation of arachidonic acid into PtdIns is attained in the presence of large amounts of docosahexaenoic acid and that several acyltransferase ... clarify the involvement of the PtdIns cycle in the accumulation of arachidonic acid in PtdIns of fish Fig Effects of docosahexaenoic acid (D...

Ngày tải lên: 08/03/2014, 08:20

... transformation coefficient on concentration of impurities when concentration of impurities nD tend toward zero, value of the parametric transformation coefficient of acoustic and optical phonons in doped superlattices ... of acoustic and optical phonons in doped superlattices depends non-linearly on concentration of impurities nD E...

Ngày tải lên: 22/03/2014, 11:20

... (Sigma) The band intensities were calculated using image j software Effects of curcumin on the dynamic instability of individual microtubules in MCF-7 cells The effects of curcumin on the dynamic instability ... off with fresh media The cells were incubated without or with curcumin for and h, and then stained with PI The effect of curcumin on t...

Ngày tải lên: 23/03/2014, 03:20

... targets and that sumoylation regulates the transcriptional activity and subnuclear localization of LRH-1 In rat granulosa cells, SUMO1-mediated subnuclear localization is attenuated by the cAMP signaling ... L), indicating that SUMO conjugation is necessary for LRH-1 localization to the nuclear bodies in rat granulosa cells Therefore, none of these...

Ngày tải lên: 23/03/2014, 06:20

... selection in laboratory populations of Drosophila Evolution, 2, 176-186 OBERTSON R F.W., REEVE E.C.R., 1952 Studies in quantitative inheritance The effects of selection of wing and thorax length in Drosophila ... more or less regular intervals over a six year period in subpopulations of the Oregon-R wild laboratory strain of Drosophila melanogaster raised in...

Ngày tải lên: 09/08/2014, 22:22

... Adenine is deaminated to hypoxanthine in DNA at only 2-3% of the rate of cytosine deamination and the deamination of guanine to xanthine is even smaller than that for adenine (Karran and Lindahl, 1980) ... tetracycline and 143 x norfloxacin Fig 4.13 Starvation mutation assay 149 Fig 4.14 Mutation pattern at stationary phase 152 Fig 4.15 Growth curve of the chvG+ str...

Ngày tải lên: 14/09/2015, 17:48

... damaging and telomeretelomerase effects and hence the mechanism of action of TQ in breast cancer cells In addition, it is of interest to investigate the effects of TQ in normal breast epithelial cells ... Black cumin seeds (left) and chemical structure of thymoquinone (right) 23 Figure 10 Growth inhibitory effects of TQ on breast cancer cells 39...

Ngày tải lên: 30/09/2015, 13:41

... RELATIVE ACTIVITY OF HOMOLOGOUS RECOMBINATION VERSUS END JOINING IN SG3 CELL LINE 62 TABLE RELATIVE ACTIVITY OF HOMOLOGOUS RECOMBINATION VERSUS END JOINING IN SOK CELL LINE 63 xi Chapter Introduction ... fish Yes Yes No Chimeric fish Yes Yes No Gynogenesis Yes Yes No ES- like cells No Yes No No Yes No genes, mapped genes and DNA markers Genetic information on wild populat...

Ngày tải lên: 22/10/2015, 21:08