Identification of immune correlates of protection in tuberculosis infection

... resulting in the production of cytokines and the subsequent killing of infected macrophages or activation of infected macrophages However, Mtb has evolved ways of evading the immune response, one of ... their help in the processing of blood samples, setting up of PPD and ESAT-6/CFP-10 stimulation assays leading to the identification of groups used in this project, an...

Ngày tải lên: 09/10/2015, 10:49

... faced in for the field of DNA vaccine development We described, for the first time, the development of a single dose/prime-boost DNA vaccine formulation for immunizing mice and guinea pigs against ... one of the following treatments, and five to ten animals were used in each group For naked DNA vaccination, the plasmid DNAhsp65 was administered by...

Ngày tải lên: 14/08/2014, 19:22

... number of sentences including any N-best time-associated words We also show the number of sentences including explicit temporal expressions, and the number of sentences including NE-TIME tag (Sekine ... obtained by the proposed method The words are sorted in the descending order of the value of P(c | w) Although some consist of two or three words, their original forms in Japan...

Ngày tải lên: 31/03/2014, 01:20

... 1 0-4 6, p70 4-7 09 doi:10.1186/147 7-7 52 5-8 -7 Cite this article as: Weis and Pasipanodya: Measuring health-related quality of life in tuberculosis: a systemic review - Response Health and Quality of ... 2009 Accepted: 19 January 2010 Published: 19 January 2010 References Guo N, Marra F, Marra C: Measuring health-related quality of life in...

Ngày tải lên: 18/06/2014, 19:20

... the analysis and interpretation of the data and finalizing the manuscript All authors read and gave approval of the final manuscript 12 13 14 15 16 Guyatt GH, Feeny DH, Patrich DL: Measuring health-related ... Health and Quality of Life Outcomes 2009, 7:14 [1,2] Although traditional clinical and biological indicators are often intrinsically related to patients' quality of l...

Ngày tải lên: 18/06/2014, 19:20

... quantification in clinical studies sors from early progressors Prognostic ability of key markers for separating healthy non -progressors from early progressors Early progressors were defined by whether ... observations in the analysis We perform this in two alternative ways in the analysis Firstly, we combine the two knee measurements into a single subject measurement by...

Ngày tải lên: 09/08/2014, 14:22

... Resolution of VAP was considered as any decrease of X-ray findings accompanied by an increase of the pO2/FiO2 ratio Antimicrobial therapy of VAP was selected by attending physicians according to published ... January 2005 Patients were hospitalized in the Department of Critical Care of the 'Evangelismos' General Hospital and in the 2nd Department of Critical Care of...

Ngày tải lên: 12/08/2014, 23:23

... List of Figures and Chart vi List of Symbols ix Chapter Introduction 1.1 A brief history of soy sauce 1.2 The methodology of preparation of soy sauce 1.3 The functional components of soy sauce ...   4.2 Content of maltol and its contribution to the TAA of dark soy sauce A considerable part of the TAA of the dark soy sauce was contained in MeOH-R a...

Ngày tải lên: 09/10/2015, 10:49

... the amino-terminal and AF-2 domain at the carboxy-terminal The DNA binding domain (DBD) is connected to the ligand binding domain (LBD) by a flexible hinge Upon ligand binding to the LBD, AF-2 ... European and Asian like the Japanese However, this has not been done in the local population Therefore, it would be of great interest to determine the SNPs in PXR, CAR...

Ngày tải lên: 09/10/2015, 11:06

... occult gastrointestinal bleeding Endoscopic evaluation of the gastrointestinal tract is commonly performed to evaluate iron deficiency Most of patients with iron deficiency in, whom gastrointestinal ... associated with GI lesions in all patients In addition, we determine the yield of endoscopy evaluations in pre-menopausal and age < 50 women with iron...

Ngày tải lên: 25/10/2012, 11:18

... mean infection FIGURE 1: PROBABILITY OF DEVELOPING TUBERCULOSIS DISEASE FOLLOWING INFECTION: INFLUENCE OF THE NUMBER OF INFECTING BACILLI, THE DURATION OF EXPOSURE AND THE COMPETENCE OF THE INDIVIDUAL’S ... available in South Africa Not available in South Africa Ciprofloxacin can be substituted for Ofloxacin Not available in South Africa 15 11 GENERAL MA...

Ngày tải lên: 15/02/2014, 12:20

... that pro and sentences are a mixture of opinions and facts, making identifying them in online reviews a distinct problem from opinion sentence identification Finally, we also apply the resulting ... Determining the Sentiment of Opinions Proceedings of COLING-04 pp 1367-1373 Geneva, Switzerland Kim, Soo-Min and Eduard Hovy 2005 Automatic Detection of Opinion Bearing Words...

Ngày tải lên: 20/02/2014, 12:20

... Facing the Reality of Drug-Resistant Tuberculosis: Challenges and Potential Solutions in India: Summary of a Joint Workshop by the Institute of Medicine, the Indian Nation FACING THE REALITY ... Facing the Reality of Drug-Resistant Tuberculosis: Challenges and Potential Solutions in India: Summary of a Joint Workshop by the Insti...

Ngày tải lên: 05/03/2014, 11:20

... Following the publication of this trial, Prasad and Singh12 updated their Cochrane systematic review on the efficacy of corticosteroids in TBM.12 The combined mortality in the control arms (anti-tuberculosis ... to play an important role in the disruption of the bloodbrain barrier in TBM Corticosteroids significantly reduce the CSF levels of MMP-9 in pa...

Ngày tải lên: 06/03/2014, 04:20

... important drug- drug interactions in the treatment of HIV-related tuberculosis are those between rifampin and the NNRTIs, efavirenz and nevirapine Rifampin is the only rifamycin available in most of the ... the key role of the rifamycins in the success of tuberculosis treatment mandates that the drug- drug interactions between the rifamycins and...

Ngày tải lên: 06/03/2014, 04:20