Development of computational methods for the rapid determination of NMR resonance assignment of large proteins

... determination is the spectral assignment procedure This involves sequence-specific resonance assignment of NMR signals and the assignment of NOESY spectra Resonance assignment forms the basis for characterizing ... obtain the assignments of the Cα and CO of the same residue Then, the CO frequency is used to obtain assignments for the HN and 15N of...

Ngày tải lên: 04/10/2015, 15:52

... evaluation of the performance of a classification algorithm The SN is the proportion of correct positive classifications out of the number of true positives The SP is the proportion of correct ... classifications out of the number of true negatives The accuracy is the total number of correct classifications out of the total number of samples The PPV...

Ngày tải lên: 14/08/2014, 17:22

... out of the use of this material Downloaded by [McGill University Library] at 07:35 15 December 2012 Comparison of the Methods for the Determination of Surface Acidity of Solid Catalysts LUCIO FORNI ... the quantity of exchanged deuterium and from the quantity of water formed during the reaction The fraction of the various forms of hydrogen ca...

Ngày tải lên: 29/07/2015, 02:27

... conventional and molecular detection methods of pathogen; (2) bioinformatics and cheminformatics in drug discovery; (3) database development; (4) virtual screening of drug discovery; (5) objectives and ... efficient and effective To help achieve this purpose, this work on "Development of Database and Computational Methods for Disease Detection and...

Ngày tải lên: 10/09/2015, 09:04

... DEVELOPMENT OF NMR METHODS FOR THE STRUCTURAL ELUCIDATION OF LARGE PROTEINS ZHENG YU (B.Sc., Xiamen University) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY DEPARTMENT OF BIOLOGICAL ... analysis of complex, x    Development of NMR methods for the structural elucidation of large proteins Summary   crowded and folded high-dime...

Ngày tải lên: 11/09/2015, 09:57

... 25 25 25 Time (h) 2.0 5.0 6.0 1.5 5.0 2.0 Yield %b (1 03:10 4) (E/Z)c 25 (1 00: 0) (8 0/2 0) 23 (1 00: 0) (8 0/2 0) 25 (7 6:2 4) (8 0/2 0) 45 (1 00: 0) (8 0/2 0) 49 (1 00: 0) (8 0/2 0) 69 (1 00: 0) (8 0/2 0) 105 105a 105b ... Yield 9a (% ) ( : ) (E/Z) 15 (7 5:2 5) (1 00/ 0) 22 (2 3:7 7)...

Ngày tải lên: 16/09/2015, 17:11

... an effort to develop an effective extraction method for bioflocculants from the microbial cell surface Materials and Methods Activated sludge samples Activated sludge samples were collected from ... was the most effective extraction method for activated sludge However, cell disruption is not effective for the isolation of bioflocculants Thus, NaOH extr...

Ngày tải lên: 05/09/2013, 09:08

... qualitative evaluation of lexical association measures, mainly for the following reasons: the instability of precision values obtained from the rst few percent of the data in the SLs; the lack of signicant ... precision values above 50% for the rst 10% of the list, but is outperformed by the t-test afterwards Looking at the rst 40% of the data, th...

Ngày tải lên: 20/02/2014, 18:20

... number of spins By linearity of the Fourier transform the direct relation between the peak integral and the number of spins of the corresponding chemical group holds for the spectrum of superposed ... derivation due to the time-dependence of the unit vectors Using the product rule for the derivation and the fact that the time derivative of the u...

Ngày tải lên: 29/05/2014, 18:32

... Standardization of Shell vial culture After adaptation of JE, WN and Dengue-2 viruses (NIV strains) to the porcine kidney cell line, the strains were used for the standardization of shell vial ... rapid diagnostic method for the diagnosis of viral encephalitis Early, prompt collection, transport and processing of the CSF samples, would make SVC a...

Ngày tải lên: 19/06/2014, 08:20

... University of California [5,6] provided a tremendous resource of knowledge related to the mechanics of human movement The work at the University of California formed the basis for many of the fundamental ... factors limiting the advancement of the study of human movement is the measurement of skeletal movement from markers or sensors placed on th...

Ngày tải lên: 19/06/2014, 10:20

... screw-cap vial for HPLC analysis and 100 µL of the working solution of the internal standard were added to each sample Then the samples were vortex mixed and a 900 µL aliquot was injected into the LC/MS/MS ... some of the structural isomers of prostaglandins, which resulted in the same parent-daughter ion transitions The whole analytical run time, including the...

Ngày tải lên: 20/06/2014, 00:20

... Standardization of Shell vial culture After adaptation of JE, WN and Dengue-2 viruses (NIV strains) to the porcine kidney cell line, the strains were used for the standardization of shell vial ... rapid diagnostic method for the diagnosis of viral encephalitis Early, prompt collection, transport and processing of the CSF samples, would make SVC a...

Ngày tải lên: 20/06/2014, 04:20

... with the Vietnamese research Institutes involved Success Alliance is also thanked for their assistance in providing information regarding the cocoa industry in Vietnam and in the establishment of ... darken in colour during drying as the majority of browning reactions will occur during this process DRYING OF COCOA Drying of cocoa is an important step in co...

Ngày tải lên: 21/06/2014, 06:20