CHEMICAL AND BIOLOGICAL CHARACTERIZATION OF LIGUSTICUM WALLICHII EXTRACT IN 3t3 l1 AND HEP g2 CELL LINES

... EFFECTS OF PHTHALIDES ON 3T3- L1 CELL LINE Hypothesis Phthalides extracts from chuangxiong influence preadipocyte proliferation and differentiation in 3T3- L1 murine cell model Introduction According ... duplication and cell division The increase of sub-G1 phase from cell cycle analysis showed that IPE had a minor or insignificant influence on apoptosis induction in...

Ngày tải lên: 03/10/2015, 20:32

... (Figs 3–5) Antioxidant defences of q0 cell lines GSH-GSSG and GR We measured GSH and GSSG in exponentially growing cells, as GSH content changes in the growth and lag phases [51] In all q0 cells studied, ... cells, and that there are cell line-to -cell line variations in intracellular antioxidant defences and ROS homeostasis In fact among the studied cel...

Ngày tải lên: 16/03/2014, 18:20

... Validation of A4 in g/L of PBS/BSA Table 5a Interday Validation of T in g/L of PBS/BSA Table 5b Intraday Validation of T in g/L of PBS/BSA Table 6a Interday Validation of DHT in g/L of PBS/BSA ... 4.3.2 Determination of Saturating Doses of Known AKR1C3 Inhibitor and Dimethoxycurcumin and its Potential as AKR1C3 Enzyme Inhibitor 126 4.3.3 Investigation of Dime...

Ngày tải lên: 09/09/2015, 08:14

... discovery of a brain- specific MT isoform, GIF, in 1991, sparked considerable interest in understanding the role of all MTs in the brain, and particularly within the injured or diseased brain In the ... studies examining the role of GIF in AD, linked to its initial discovery as a factor deficient in the AD brain There remains no clear consensus on the...

Ngày tải lên: 16/02/2014, 15:20

... mgÆmL)1 BSA and stored at )20 °C Electrogenic BSP uptake inhibition by antibodies The kinetics of bilitranslocase transport activity inhibition by antibodies were examined by preincubating 24 lL ... addition of protein (2.6 ± 0.04 lmolÆmin)1Æmg protein)1, with lg valinomycin), as well as of K+ (6.25 ± 0.16 unitsÆmEq)1 K+, with lg valinomycin) and valinomycin (0.5...

Ngày tải lên: 20/02/2014, 01:20

... in the higher activity observed in Vasconcellea spp.: (1) a higher protein content in their latex; and (2) the presence of other cysteine proteinases or isoforms in the latex To investigate these ... relationships of cysteine proteinases it can be deduced that the common ancestor of the genera Carica and Vasconcellea already contained at least two d...

Ngày tải lên: 07/03/2014, 11:20

... than the activity in the precipitate from the Ca1 transfected cells demonstrating that the Cb2 antibody in combination with PKA kinase assay could be used to detect specifically Cb2 activity To ... PKA- specific kinase activity, as shown in Fig 4B This demonstrated that precipitates extracted with 8-CPTcAMP contained cAMP-inducible PKA activity that could be inhibited by protein kina...

Ngày tải lên: 16/03/2014, 18:20

... Aggregation domain in myosin light chain kinase A Fig Prediction for a conserved aggregation domain in the 4Ig region of L-MLCK and recombinant expression of MLCK variants (A) The sequences of ... necrosis factor-induced long myosin light chain kinase transcription is regulated by differentiation-dependent signaling events: characterization of the hum...

Ngày tải lên: 30/03/2014, 04:20

... showing province and number of measles virus isolates obtained during 2000- 2001 Figure virus isolates obtained during 2000 2001 Map of Turkey showing province and number of measles Map of Turkey ... COBL COBL COBL urine urine urine urine urine urine urine throat swab urine urine throat swab nasal swab urine urine urine urine throat swab urine urine urine blood blood...

Ngày tải lên: 19/06/2014, 08:20

... showing province and number of measles virus isolates obtained during 2000- 2001 Figure virus isolates obtained during 2000 2001 Map of Turkey showing province and number of measles Map of Turkey ... COBL COBL COBL urine urine urine urine urine urine urine throat swab urine urine throat swab nasal swab urine urine urine urine throat swab urine urine urine blood blood...

Ngày tải lên: 20/06/2014, 04:20

... coordination bonds Conclusions In this letter, two monodispersed copper colloids in water and E.G have been prepared In order to obtain pure-phase copper colloid in water, the reaction time of ... structure of a polyvinyl skeleton with nitrogen and oxygen polar groups, and the polar group donates lone-pair electrons forming a coordinative interaction with copper...

Ngày tải lên: 22/06/2014, 01:20

... is in accordance with the highly increased cytokine and chemokine secretion induced by poly(I:C) and emphasizes the strong proinflammatory impact of the TLR3 ligand poly(I:C) for SAEC Regulation ... expression of other TLRs and proteins involved in TLR signaling in SAEC In addition, we demonstrate that the expression of TLRs and their signaling p...

Ngày tải lên: 11/08/2014, 08:21

... frequency and distribution of SSRs in castor bean ESTs, (2) the establishment and validation of EST- SSR markers for detection of polymorphism in castor bean, and (3) the assessment of genetic ... an increasing need for distinguishing the varieties reliably, establishing their purity, and fingerprinting released varieties, hybrids and the parental l...

Ngày tải lên: 11/08/2014, 11:21

... Immunoperoxidase staining of skin in SSc patients compared with that in healthy controls Skin sections from (a to c) healthy controls and (d to f) systemic sclerosis (SSc) patients were stained with anti-human-CD68, ... no link between CD163+ or CD204+ monocyte/macrophage lineage and SSc has been established in the skin or in the peripheral blood of...

Ngày tải lên: 12/08/2014, 14:22

... subpopulations in NO2-exposed animals The occurrence of phenotypically different AM subpopulations may either be explained by a functional shift of already present AM or by the infiltration of macrophages ... [39,40] In conclusion, our findings clearly suggest that the newly recruited ED7+ AM are involved in the regulation of the ongoing inflammatory process Wh...

Ngày tải lên: 12/08/2014, 16:20