Characterization of statins induced DDX20 silencing in invasive breast cancers

... exploitation of DDX20 as a potential therapeutic marker for statins and the understanding of the functional relevance of miR-222 to statins- induced apoptosis in invasive breast cancers ix LIST OF TABLES ... identified DDX20 as a crucial player in the metastasis of breast cancers, where DDX20 increases the invasiveness of breast cancers through activati...

Ngày tải lên: 01/10/2015, 17:27

... exploitation of DDX20 as a potential therapeutic marker for statins and the understanding of the functional relevance of miR-222 to statins- induced apoptosis in invasive breast cancers ix LIST OF TABLES ... identified DDX20 as a crucial player in the metastasis of breast cancers, where DDX20 increases the invasiveness of breast cancers through activati...

Ngày tải lên: 03/10/2015, 20:32

... content of rat lungs Hydroxyproline content of rat lungs There was no significant difference in the hydroxyproline content of the four groups at days after instillation The hydroxyproline content of ... obviously by Lv-shCD36 Accordingly, CD36 may participate in the activation process of L-TGFβ1 in the early phase of the experimental silicosis Furthermore, si...

Ngày tải lên: 12/08/2014, 14:20

... micro- fabricated cantilevers were used to investigate the stresses and density changes upon crystallization in amorphous thin films Two classes of materials with distinct properties and significant ... of Young’s modulus and coefficients of thermal expansion of amorphous Cu-Zr thin films - 162 7.1 Measurement of Young’s modulus of amorphous Cu-Zr...

Ngày tải lên: 11/09/2015, 09:16

... prevalence of B19 infection in livers from patients with fulminant hepatitis and biliary atresia Interestingly, all fulminant hepatitis patients infected with B19 had the replicative form of B19 mRNA ... prevalence of B19 infection not only in fulminant hepatitis patients, but also in biliary atresia patients However, all fulminant hep...

Ngày tải lên: 26/10/2012, 10:03

... seen in the putative T-box DNA-binding domain of t-bet, the STAT protein interaction domain, STAT protein all-alpha domain, STAT protein DNA-binding domain and SH2 domain of stat6, and the zinc-finger ... implicated in other protein–protein interactions, a STAT protein DNA-binding domain and an SH2 domain, which binds phosphorylated tyrosine residues in the context...

Ngày tải lên: 16/02/2014, 09:20

... accumulation of citrulline in wild watermelon As a first step to understand the mechanism of citrulline and arginine accumulation in wild watermelon, we focused on the fifth step of citrulline biosynthesis, ... thermotolerance and insensitivity to inhibition by downstream products, citrulline and arginine Results The enzyme involved in catalysis of the fi...

Ngày tải lên: 20/02/2014, 03:20

... of PrPC-induced cell drug resistance in gastric cancer cells PI3K/Akt is involved in the activation of P-gp by PrPC in gastric cancer To further investigate the underlying mechanism of PI3K/Akt- mediated ... significantly increased The results indicate that inhibition of the PI3K/Akt signaling pathway may lead to inhibition of the MDR indu...

Ngày tải lên: 07/03/2014, 03:20

... N-terminal processing of CGA in rat heart extracts Our data reveal the presence of several vasostatin I-containing and vasostatin II-containing peptides in the CGA(1–199) domain, strongly supporting ... proenkephalin-A in bovine chromaffin cells Identification of natural derived fragments by Vasostatin-containing peptides in rat heart 57 58 59 60 61 62 63 64 65 66...

Ngày tải lên: 07/03/2014, 12:20

... Divergences of rat alkaline phosphatase isozymes T Harada et al A B Fig Stereoviews of the residues near metal-binding site in (A) rat intestinal alkaline phosphatase- I (rIAP-I) and (B) rIAP-II ... Residues indirectly associating with the metal via water molecules Fig Immunological detection of rat intestinal alkaline phosphatase (rIAP) isozymes in rat...

Ngày tải lên: 07/03/2014, 17:20

... Schweda, E.K.H (2001) A rapid and sensitive procedure for determination of 5-N-acetyl neuraminic acid in lipopolysaccharides of Haemophilus in uenzae: a survey of 24 nontypeable H in uenzae strains ... HexNAc1ÆHex5ÆHep4ÆAnKdo-ol (Tables and 4) The Table Negative ion ESI-MS data and proposed compositions for O-deacylated lipopolysaccharide (LPS-OH) of nontypeable Hae...

Ngày tải lên: 08/03/2014, 02:21

... DNA binding domain and VP16 activation domain Various combinations of the EcR ligand binding domain, VP16 activation domain and GAL4 DNA binding domain were constructed (Fig 1A) and tested in NIH ... probably in uence the behavior of fusion protein upon binding to ligand Apparently, having activation domain (VP16) and DNA binding domain (GAL4), in that order, on the NH2-terminal end...

Ngày tải lên: 16/03/2014, 12:20

... Adjustments of the cell fractionation protocol involved reducing the starting material and the volume of the sucrose layers but maintaining the relative ratios of the sucrose layers Infected Sf9 ... an N-glycosylation consensus sequence of a membrane protein, the segment containing the tripeptide sequence must enter the lumen of the ER, which becomes the ex...

Ngày tải lên: 16/03/2014, 13:20

... Pentaacyl lipid A and tetraacyl lipid A (synthetic compound 406) form lamellar structures, which can be related to a cylindrical molecular shape, and are agonistically inactive, but may be antagonistic, ... 1.2 Incorporation into phospholipid cell membranes As a prerequisite for agonistic as well as antagonistic activity, the intercalation of endotoxins into target cell membr...

Ngày tải lên: 23/03/2014, 13:20

... this minireview is to summarize what is currently known about the molecular mechanisms of osmotic stress resistance, osmosensing and signal transduction in C elegans Osmosensing and signaling in ... process of interest, allows genes to be ordered into pathways, and can provide important and novel mechanistic insights into the molecular structure and functio...

Ngày tải lên: 30/03/2014, 03:20