MECHANISTIC CHARACTERISATION OF DENGUE VIRUS RNA DEPENDENT RNA POLYMERASE NON NUCLEOSIDE INHIBITOR BINDING POCKET THROUGH IN VITRO BIOCHEMICAL ASSAYS AND REVERSE GENETICS ANALYSES
MECHANISTIC CHARACTERISATION OF DENGUE VIRUS RNA DEPENDENT RNA POLYMERASE NON NUCLEOSIDE INHIBITOR BINDING POCKET THROUGH IN VITRO BIOCHEMICAL ASSAYS AND REVERSE GENETICS ANALYSES
... MECHANISTIC CHARACTERIZATION OF DENGUE VIRUS RNA DEPENDENT RNA POLYMERASE NON- NUCLEOSIDE INHIBITOR BINDING POCKET THROUGH IN VITRO BIOCHEMICAL ASSAYS AND REVERSE GENETICS ANALYSES Dorcas ... entitled "Mechanistic Characterization of Dengue Virus RNA Dependent RNA Polymerase Non- Nucleoside Inhibitor Binding Pocket through...
Ngày tải lên: 02/10/2015, 17:14
Báo cáo sinh học: " Nucleocapsid formation and RNA synthesis of Marburg virus is dependent on two coiled coil motifs in the nucleoprotein" pot
... coiled coil motif in NP is critical for the homooligomerization of NP, formation of NP-induced intracellular inclusions, interaction of NP with VP35 and for the function of NP in RNA synthesis ... following hypothesis The two coiled coil motifs are involved in intra- and intermolecular binding While C1 is involved in intermolecular binding betwe...
Ngày tải lên: 18/06/2014, 18:20
Báo cáo hóa học: " Nucleocapsid formation and RNA synthesis of Marburg virus is dependent on two coiled coil motifs in the nucleoprotein" pdf
... coiled coil motif in NP is critical for the homooligomerization of NP, formation of NP-induced intracellular inclusions, interaction of NP with VP35 and for the function of NP in RNA synthesis ... hypothesis The two coiled coil motifs are involved in intra- and intermolecular binding While C1 is involved in intermolecular binding between NP mole...
Ngày tải lên: 20/06/2014, 01:20
Báo cáo khoa học: "Small interference RNA profiling reveals the essential role of human membrane trafficking genes in mediating the infectious entry of dengue virus" pdf
... as: Ang et al.: Small interference RNA profiling reveals the essential role of human membrane trafficking genes in mediating the infectious entry of dengue virus Virology Journal 2010 7:24 Submit ... essential for mediating the infectious entry process of DENV into cells siRNA profiling of human membrane trafficking genes required...
Ngày tải lên: 12/08/2014, 04:21
Báo cáo sinh học: " Open Access Cloning of the canine RNA polymerase I promoter and establishment of reverse genetics for influenza A and B in MDCK cells" docx
... http://www.virologyj.com/content/4/1/102 A < /b> HindIII XbaI BamHI BamHI BamHI AvrII SpeI EcoRI SpeI HindIII SphI XbaI XbaI BamHI * XbaI BamHI BamHI SacI BamHI * EcoRI BamHI SacI BamHI BamHI AvrII 18S rRNA Gene MDCK Eco RI 7.1 kb Fragment ... influenza < /b> using the < /b> RNA < /b> pol I < /b> transcription machinery in canine < /b> cells, cloning < /b> the < /b> canine < /b>...
Ngày tải lên: 18/06/2014, 18:20
Báo cáo sinh học: " Peptide inhibitors of dengue virus and West Nile virus infectivity" pot
... mimics of the fusion proteins of other retroviruses, and of orthomyxoviruses, paramyxoviruses, filoviruses, coronaviruses, and herpesviruses have also been identified and shown to inhibit viral ... Figure combination Inhibitory effect of peptides WN53 and DN59 alone and in Inhibitory effect of peptides WN53 and DN59 alone and in combination WN53 and DN59 peptides wer...
Ngày tải lên: 19/06/2014, 08:20
Báo cáo sinh học: " Strategically examining the full-genome of dengue virus type 3 in clinical isolates reveals its mutation spectra" ppt
... 0–7 .3 0–6.7 17/7748 31 /10 132 33 /10728 47/14900 46/9 536 52/15496 2.2 3. 1 3. 1 3. 2 4.8 3. 4 3. 3 ± 0.8 4.1 3. 5 6.1 3. 6 6.8 6.5 5.1 ± 1.5 5/17005 16/24165 9/ 232 70 16/2 237 5 25/20585 8/16110 29/ 233 35 32 /30 515 ... ratio in domain III of viral isolates 3H was caused by the value of of dS at the denominator The positive selection on the domain III is not su...
Ngày tải lên: 19/06/2014, 08:20
Báo cáo hóa học: " Cloning of the canine RNA polymerase I promoter and establishment of reverse genetics for influenza A and B in MDCK cells" pdf
... http://www.virologyj.com/content/4/1/102 A < /b> HindIII XbaI BamHI BamHI BamHI AvrII SpeI EcoRI SpeI HindIII SphI XbaI XbaI BamHI * XbaI BamHI BamHI SacI BamHI * EcoRI BamHI SacI BamHI BamHI AvrII 18S rRNA Gene MDCK Eco RI 7.1 kb Fragment ... influenza < /b> using the < /b> RNA < /b> pol I < /b> transcription machinery in canine < /b> cells, cloning < /b> the < /b> canine < /b>...
Ngày tải lên: 20/06/2014, 01:20
Báo cáo hóa học: " Comparative analysis of full genomic sequences among different genotypes of dengue virus type 3" pdf
... among various regions of full- length sequences of different genotypes of DENV-3 With the lack of full- length sequences of viruses belonging to old American genotype IV, only four DENV-3 genotypes, ... http://www.virologyj.com/content/5/1/63 Table 4: Comparison of sequence diversity (p-distance, %) of full- length genomic sequences among different genotyp...
Ngày tải lên: 20/06/2014, 01:20
Báo cáo hóa học: " Simultaneous circulation of genotypes I and III of dengue virus 3 in Colombia" docx
... Ecuador00b I I I I I I I I I I I I I I I I I I I I I I (V)b I (V)b I (V)b II II II II II II II II II II II II II II II III III III III III III III III III III III III III III III III III III III III 1998 ... Asia/S.Pacific (I) India (III) India (III) India (III) India (III) India (III) India (III) India (III) India (III) India (III) India (III) In...
Ngày tải lên: 20/06/2014, 01:20
Báo cáo hóa học: " Reemergence of dengue virus type-3 (subtype-III) in India: Implications for increased incidence of DHF & DSS" docx
... outbreak in northern India in 2003 and its continued dominance again in 2004 indicates the resurgence of dengue- 3 in a dominant form The emergence of a newer dengue serotype after an interval ... III) The reemergence of highly fatal subtype III of DEN-3 in a dominant form, replacing the earlier circulating subtype IV of DEN-2 in India is a matter of great concern...
Ngày tải lên: 20/06/2014, 01:20
báo cáo hóa học:" Peptide inhibitors of dengue virus and West Nile virus infectivity" doc
... mimics of the fusion proteins of other retroviruses, and of orthomyxoviruses, paramyxoviruses, filoviruses, coronaviruses, and herpesviruses have also been identified and shown to inhibit viral ... Figure combination Inhibitory effect of peptides WN53 and DN59 alone and in Inhibitory effect of peptides WN53 and DN59 alone and in combination WN53 and DN59 peptides wer...
Ngày tải lên: 20/06/2014, 04:20
báo cáo hóa học:" Strategically examining the full-genome of dengue virus type 3 in clinical isolates reveals its mutation spectra" doc
... 0–7 .3 0–6.7 17/7748 31 /10 132 33 /10728 47/14900 46/9 536 52/15496 2.2 3. 1 3. 1 3. 2 4.8 3. 4 3. 3 ± 0.8 4.1 3. 5 6.1 3. 6 6.8 6.5 5.1 ± 1.5 5/17005 16/24165 9/ 232 70 16/2 237 5 25/20585 8/16110 29/ 233 35 32 /30 515 ... ratio in domain III of viral isolates 3H was caused by the value of of dS at the denominator The positive selection on the domain III is not su...
Ngày tải lên: 20/06/2014, 04:20
Báo cáo y học: "Effect of small interference RNA (siRNA) for ADAMTS5 on intervertebral disc degeneration in the rabbit anular needle-puncture model" pptx
... interfering of disc degenerationchanges after injection of control small interfering RNA (siRNA) or ADAMTS5 siRNA in the rabbit anular puncture model of disc degeneration Eight weeks after the control ... degeneration interfering RNA (siRNA) injection in assessment weeks after small Magnetic resonance imaging (MRI) the rabbit anular puncture m...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo y học: " Evolution of Dengue Virus Type 3 Genotype III in Venezuela: Diversification, Rates and Population Dynamics" docx
... found in DENV -3 genotype III of strains circulating in the South American region In order to map the amino acid substitutions found on the E protein structure of DENV -3 genotype III strains of the ... initial years of the introduction in the continent (1994-2000) and strains isolated in the Latin American region in recent years (see Figure 1) In this study,...
Ngày tải lên: 12/08/2014, 02:20