Conjugated polymer nanoparticles for bioimaging applications

... CONJUGATED POLYMER NANOPARTICLES FOR BIOIMAGING APPLICATIONS GENG JUNLONG (M.S University of Science and Technology of China) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR ... PUBLICATIONS 151 vi SUMMARY Conjugated polymer nanoparticles (CP NPs) have emerged as an attractive fluorescent probe in bioimaging as well as other biological applications due to their large ......

Ngày tải lên: 30/09/2015, 05:39

... (pH 7.4) For siRNA delivery experiments, protoplasts were cultured in cell wall regeneration medium siRNA delivery to protoplasts and intact BY-2 cells Protoplasts (1 × 106mL-1) or intact BY-2 cells ... SL, Papahadjopoulos D: Liposome-mediated delivery of tobacco mosaic virus RNA into tobacco protoplasts: A sensitive assay for monitoring liposome-protoplast interaction...

Ngày tải lên: 11/08/2014, 11:21

... BETA- CYCLODEXTRIN CONJUGATED MAGNETIC NANOPARTICLES FOR BIO- AND ENVIRONMENTAL APPLICATIONS ABU ZAYED MD BADRUDDOZA (B.Sc., Bangladesh University ... 2-1 Materials used for coating or encapsulating iron oxide magnetic nanoparticles and their bio- and environmental applications 14  Table 2-2 List of magnetic separation applications [12] ... uncoated magne...

Ngày tải lên: 10/09/2015, 15:52

... ligand influence nanoparticle tumor localization or uptake? Trends Biotechnol 2008, 26:552 doi:10.1186/1556-276X-6-563 Cite this article as: Hou et al.: Both FA- and mPEG-conjugated chitosan nanoparticles ... mPEG-conjugated chitosan nanoparticles for targeted cellular uptake and enhanced tumor tissue distribution Nanoscale Research Letters 2011 6:563 Subm...

Ngày tải lên: 20/06/2014, 22:20

... the rate of Cu release (see Discussion) In vitro toxicity of CuCNPs in HeLa cells The in vitro toxicity of CuCNPs in HeLa cells (a cervical adenocarcinoma) was investigated via an assay based ... platinum: synthesis, characterization, and in vitro toxicity of Cu(II)-releasing polymer nanoparticles for potential use as a drug delivery...

Ngày tải lên: 21/06/2014, 02:20

... Institute for BioNanotechnology in Medicine Advantages of Polymer Therapeutics “Using advanced polymer chemistry and precision engineering at the molecular level, together with an appreciation of the ... favors polymer formation due to the alleviation of ring strain • Highly functional group tolerant, works at mild temperature • Amenable to the synthesis of monodispers...

Ngày tải lên: 23/08/2015, 18:48

... more recently in biotechnology/biomedicine [13] Some of the more specific biomedical applications of magnetic nanoparticles include their use as magnetic contrast agents in magnetic resonance ... allowed for the production, characterization and functionalization of magnetic nanoparticles for specialized clinical applications Extensive research has been done on use o...

Ngày tải lên: 14/09/2015, 14:03

... the dyes in different media can be proposed Near Infrared Dyes ( NIR ) for Bioimaging: In recent years, fluorescence imaging using Near Infrared dyes has attracted much attention as it affords ... and polarization.11 For fluorescence -based bioimaging, the optimum wavelength for excitation and emission ranges from 650–900 nm.12 This range of wavelength is called Near...

Ngày tải lên: 16/10/2015, 11:58

... PF polyfluorene xv List of abbreviations PFVP poly(fluorene-divinylene-phenylene) pI isoelectric point PL photoluminescence PLC phospholipase c pNA p- nitroanilide PNA peptide nucleic acid PPP ... representative CPs, including polyacetylenes (PAs), poly(arylene vinylene)s (PAVs), poly(para-phenylene)s (PPPs), polyfluorenes (PFs), poly(arylene ethynylene)s (PAEs), polyanilines (PANIs), polypy...

Ngày tải lên: 09/09/2015, 10:17

... IN VITRO AND IN VIVO EVALUATION OF TRANSFERRIN- CONJUGATED LIPID SHELL AND POLYMER CORE NANOPARTICLES FOR TARGETED DELIVERY OF DOCETAXEL PHYO WAI MIN (M.B.,B.S (YGN) U.M(1)) ... the synthesis and characterization of transferrin conjugated lipid shell and polymer core nanoparticles are discussed in Chapter In Chapter 5, in vitro...

Ngày tải lên: 09/10/2015, 11:18

... can be exploited for use in a variety of different applications including cellular imaging and delivery The major types of nanoparticles that have been used for cellular imaging include polymer/biomacromolecular ... be transformed into a non-fluorescent state upon initial illumination (termed blinking) This blinking may result in a false negative fluorescence reading during shor...

Ngày tải lên: 22/06/2014, 18:20

... found in clinical patients In our previous reports, photosensitizer -conjugated magnetic nanoparticles were successfully used for in vivo simultaneous magnetofluorescent imaging and targeting therapy ... Resonance Imaging, investigated the feasibility of as-prepared nanoprobes for non-invasive in vivo targeted dual modal imaging of gastric cancer Results sh...

Ngày tải lên: 11/08/2014, 00:23

... SURFACE MODIFICATION OF FERROMAGNETIC NANOPARTICLES FOR SEPARATION OF TOXIC HEAVY METALS AND ENVIRONMENTAL APPLICATIONS ZAYED BIN ZAKIR SHAWON B.Sc (Chemical ... cost of separation of detrimental pollutants like heavy metals Recently, scientists have focused on the development of the nanomaterials as adsorbents for the separations of biomolecules,...

Ngày tải lên: 08/09/2015, 19:41

...     SURFACE FUNCTIONALIZATION OF SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES FOR POTENTIAL CELL TARGETING, IMAGING, AND CANCER THERAPY APPLICATIONS HUANG CHAO (B.ENG., ... Objectives and Scopes The overall aim of this thesis is to develop various functional polymers as surface coatings of SPIONs for potential cell targeting, MRI, and cancer...

Ngày tải lên: 09/09/2015, 10:14

... PLGA nanoparticles loaded with paclitaxel (WNP) could improve the delivery of paclitaxel to colonic cancer cells Glycosylation patterns of representative colon cancer cells (Caco-2 and HT-29 cells) ... cytotoxicity profile of blank WGA -conjugated PLGA nanoparticles against colon cells (a) positive and negative control; (b) Caco-2 cells; (c) HT-29 cells; (d...

Ngày tải lên: 14/09/2015, 08:37