Protein function and inhibitor prediction by statistical learning approach
Protein function and inhibitor prediction by statistical learning approach
... Results and Discussion 94 5.2 Prediction of Functional Class of Novel Viral Proteins (Paper V) 101 II Protein function and inhibitor prediction by statistical learning approach ... protein functional families and protein inhibitors by statistical machine learning approach Development of methods and computational tools for the prediction of functional fa...
Ngày tải lên: 16/09/2015, 08:31
Prediction of novel biochemical class disease related proteins and microRNAs by machine learning approach
... 4.1.2 Prediction performance for antimicrobial proteins 68 Prediction of novel biochemical class, disease related proteins and microRNAs by machine learning approach III 4.1.3 Prediction of novel ... characterization of MFEs Prediction of novel biochemical class, disease related proteins and microRNAs by machine learning approac...
Ngày tải lên: 11/09/2015, 09:10
Báo cáo khoa học: A1–Protein Function and Ageing pptx
... Longevity and survival factors implicated in human ageing and longevity E Gonos Molecular and Cellular Ageing, National Hellenic Research Foundation, Athens, Greece E-mail: sgonos@eie.gr Ageing and ... 150 and 47 lm, for BChE w.t 320 and 23 lm for 2-PAM and HI-6, respectively Introduced mutations lowered oxime binding affinities for both oximes, and Ki were 590 and 87 lm...
Ngày tải lên: 23/03/2014, 15:20
INVESTIGATION OF EXAFS CUMULANTS OF SILICON AND GERMANIUM SEMICONDUCTORS BY STATISTICAL MOMENT METHOD PRESSURE DEPENDENCE
... Fig 1a Pressure dependence of NND of Ge Fig 1b Pressure dependence of volume of Ge Fig 2a Temperature dependence of DWF of Ge Fig 2b Pressure dependence of DWF of Ge In Fig.3a, we plot the pressure ... INVESTIGATION OF EXAFS CUMULANTS OF SILICON AND 115 Fig 3b Pressure dependence of volume of Ge Fig 4a Temperature dependence of DWF of...
Ngày tải lên: 30/10/2015, 19:44
Báo cáo y học: "Strong inhibition of TNF-α production and inhibition of IL-8 and COX-2 mRNA expression in monocyte-derived macrophages by RWJ 67657, a p38 mitogen-activated protein kinase (MAPK) inhibitor" ppt
... Effect of RWJ 67657 on phosphorylation of p38 MAPK and MAPKAPK-2 (a) Representative presentation of phosphorylation of p38 mitogen-activated protein kinase (MAPK) in monocyte-derived macrophages after ... R389 p38 MAPK activity in RA is found predominantly in the synovial lining layer and in endothelial cells in the synovium [10] The lining layer co...
Ngày tải lên: 09/08/2014, 01:23
phylogenetic approaches to protein function prediction and protein network analysis
Ngày tải lên: 13/11/2014, 15:55
Tài liệu Báo cáo khoa học: Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth – structure and function of the second kinase noncatalytic C-lobe domain docx
... PDZ -domain- containing (FRMPD2) [8] and Ras guanine exchange factor (RasGEF) veryKIND (v-KIND, or kinase noncatalytic C-lobe domain containing 1) [9] The KIND domain in these proteins is localized to the ... determined the structural and functional properties of the protein protein interaction between v-KIND and MAP2 We defined the binding core regi...
Ngày tải lên: 14/02/2014, 19:20
Tài liệu Computer and Internet Use by Children and Adolescents in 2001: Statistical Analysis Report pptx
... How children and adolescents use home computers and the Internet? Where children and adolescents use computers? Where they use the Internet? How many users use the Internet in only one place, and ... and family income Computer and Internet use by children and adolescents is widespread and begins at an early age About nine in ten Americans ag...
Ngày tải lên: 18/02/2014, 00:20
Tài liệu Báo cáo khoa học: Relationships between structure, function and stability for pyridoxal 5¢-phosphate-dependent starch phosphorylase from Corynebacterium callunaeas revealed by reversible cofactor dissociation studies doc
... catalytic activity and stability We chose starch phosphorylase from Corynebacterium callunae (CcStP), which has been characterized biochemically and structurally [15,16], for particular reason ... concentration of between 0.0 and 100 lM was added to reconstitute the holo-enzyme The reaction was carried out at 30 C and typically, the time ể FEBS 2004 Cofactor dissociat...
Ngày tải lên: 19/02/2014, 16:20
Tài liệu Báo cáo Y học: Control of p70 ribosomal protein S6 kinase and acetyl-CoA carboxylase by AMP-activated protein kinase and protein phosphatases in isolated hepatocytes pot
... partially, the inactivation of p70S6K by rapamycin (Fig 7, upper panel) This antagonism corresponded to an inhibition of p70S6K dephosphorylation by calyculin A Indeed, the phosphorylation state of p70S6K ... pattern of activation of ACC and p70S6K in hepatocytes incubated with glutamine, suggesting a common point of control in their signalling pathways (Fig 1) The e...
Ngày tải lên: 22/02/2014, 07:20
Báo cáo khoa học: Protein aggregation and amyloid fibril formation prediction software from primary sequence: towards controlling the formation of bacterial inclusion bodies pot
... calculated and reported, such as the average a4v in each hot-spot, the area of the aggregation profile above the HST, the total area (the HST being the zero axis) and the area above the HST of each ... set of 23 well-known amyloidogenic proteins and (c) guidance towards applying this software as a useful tool for improving the solubility of recombinant pr...
Ngày tải lên: 06/03/2014, 00:20
Báo cáo khoa học: Haptoglobin binds the antiatherogenic protein apolipoprotein E – impairment of apolipoprotein E stimulation of both lecithin:cholesterol acyltransferase activity and cholesterol uptake by hepatocytes pdf
... triplicate The data are reported as percentage of the value obtained by incubation of Hpt alone, and expressed as mean ± SEM A single representative of at least three independent experiments is ... respectively After incubation, the cell were lysed for measurement of their radioactivity and protein concentration The amount of cholesterol internalized by the cel...
Ngày tải lên: 07/03/2014, 00:20
Báo cáo khoa học: Protein transport in organelles: The composition, function and regulation of the Tic complex in chloroplast protein import pptx
... in protein protein interaction are blue and the dehydrogenase domains of Tic3 2 and Tic6 2 are shown in green Tic1 10 contains two transmembrane domains at the proximal N-terminus The topology of ... surprising to find proteins with redox-active domains as Tic constituents Up to now, the ‘regulon’ of the Tic complex comprises three proteins: Tic6 2, Tic3 2...
Ngày tải lên: 07/03/2014, 03:20
Báo cáo Y học: High affinity binding between laminin and laminin binding protein of Leishmania is stimulated by zinc and may involve laminin zinc-finger like sequences doc
... lysed in 100 lL of SDS/PAGE sample buffer by boiling for min, proteins were resolved by means of 7.5% SDS/PAGE and analysed by immunoblotting with monoclonal anti-(P-Tyr) antibody followed by ... Evidence of a laminin binding protein on the surface of Leishmania donovani Biochem Biophys Res Commun 226, 101–106 Ghosh, A., Bandyopadhyay, K., Kole, L & Das, P.K (1999) I...
Ngày tải lên: 08/03/2014, 23:20
Báo cáo khoa học: pyr RNA binding to the Bacillus caldolyticus PyrR attenuation protein – characterization and regulation by uridine and guanosine nucleotides potx
... of the B caldolyticus PyrR protein to each of the three binding loops (Fig 2A–C) Binding was specific for pyr RNA, as shown by the failure of a control RNA (i.e the antisense strand to BcBL1) to ... 2A) On the other hand, in the presence of 0.5 mm UMP, which stimulated binding for all three binding loops, RNA binding to PyrR PyrR binding to Bc...
Ngày tải lên: 16/03/2014, 06:20