Dysfunctional signaling pathway for nitric oxide production in endothelial cells chronically exposed to high glucose or high fatty acids

... DYSFUNCTIONAL SIGNALING PATHWAY FOR NITRIC OXIDE PRODUCTION IN ENDOTHELIAL CELLS CHRONICALLY EXPOSED TO HIGH GLUCOSE OR HIGH FATTY ACIDS TANG YANXIA (B SC., M SC., TONGJI MEDICAL ... uncertain In other words, whether one or several steps of the 46 Introduction signaling pathway for NO production are affected by glucose or fatty acids...

Ngày tải lên: 15/09/2015, 17:09

... as: Brodsky et al.: The anti-inflammatory effects of the tellurium redox modulating compound, AS101, are associated with regulation of NFB signaling pathway and nitric oxide induction in macrophages ... kinetics I At h, AS101 probably enters the nucleus and may interfere with the DNA-binding ability of the NFB complex resulting in...

Ngày tải lên: 11/08/2014, 08:22

... conducted to examine the potential use of the novel β-glucan purified from P polymyxa JB115 as an immunostimulant or as an adjuvant of some animal vaccines β-glucan-induced nitric oxide production ... by β-glucan (Fig 4) Finally, the mRNA expression of various cytokines was investigated in RAW264.7 macrophages which were exposed to β-glucan or LPS P polymyxa JB115 β-glu...

Ngày tải lên: 07/08/2014, 23:22

... medicinal plant Artemisia herba alba on Th1 and Th2 cytokines and nitric oxide production Methods: The modulatory effects of flavonoùds extracted from Artemisia herba alba on cytokines and nitric ... Ex vivo effects of flavonoùds extracted from Artemisia herba alba on cytokines and nitric oxide production in Algerian p...

Ngày tải lên: 11/08/2014, 03:20

... requires both mitogen-activated protein (MAP) kinase and nuclear factor-jB (NF-jB) activation Results AGE-human serum albumin (HSA) and LPS stimulate a time- and dose-dependent cytokine ⁄ chemokine production ... NF-jB, indicating a predominant role of the p38 pathway in the AGE-HSA and LPS amplified in ammatory response Furthermore, blockade of both MAP kinas...

Ngày tải lên: 30/03/2014, 01:20

... describing heroin intoxication in a baby chronically exposed to heroin and cocaine, probably caused by the combined effect of chronic exposure through the placenta (pre-natal), breast milk and skin (post-natal) ... by alternative matrices Ther Drug Monit 2010, 32:1-2 doi:10.1186/1752-1947-5-288 Cite this article as: Joya et al.: Acute heroin intoxication in a b...

Ngày tải lên: 10/08/2014, 23:21

... well as NO production Accordingly, we concluded that the enhancing effect of TS on LPS/IFN -induced NO production is caused by enhancement of iNOS protein induction Effects of a-T and its derivatives ... amphiphilic structure of the polar carboxyl moiety and the hydrophobic isoprene moiety The enhancing effect of TS on LPS/IFN -induced NO production was inh...

Ngày tải lên: 22/02/2014, 04:20

... also upregulate MMP synthesis and activity in joint chondrocytes and cartilage [15] In vivo in an OA animal model, selective inhibition of the inducible nitric oxide synthase (iNOS) provides a protective ... endothelin-1 (ET-1) on nitric oxide (NO) release and inducible nitric oxide synthase (iNOS) expression by human osteoarthritis (OA) chondrocytes chondrocytes N...

Ngày tải lên: 09/08/2014, 06:22

... this article as: Furuya et al.: Suppression of nitric oxide production from nasal fibroblasts by metabolized clarithromycin in vitro Journal of Inflammation 2010 7:56 Submit your next manuscript ... examined by ELISA Data are the mean OD at 450 nm ± SE of five different subjects LPS, lipopolysaccharide; NPFs, nasal polyp fibroblasts; CAM, clarithromycin; CAM,...

Ngày tải lên: 11/08/2014, 03:20

... this article as: Furuya et al.: Suppression of nitric oxide production from nasal fibroblasts by metabolized clarithromycin in vitro Journal of Inflammation 2010 7:56 Submit your next manuscript ... examined by ELISA Data are the mean OD at 450 nm ± SE of five different subjects LPS, lipopolysaccharide; NPFs, nasal polyp fibroblasts; CAM, clarithromycin; CAM,...

Ngày tải lên: 11/08/2014, 06:22

... 2.2.5 Physical and alkaline pretreatment with saccharification Alkaline pretreatment and saccharification was examined by adding 3.3 g of wheat straw in 100 ml monoethanolamine solution in a 200 ... 2, 1.6 g of wheat straw was mixed in 50 ml of sterilized distilled water in 100 ml shaker flask and autoclaved at 135°C for h During Experiment and 4, 1.6 g...

Ngày tải lên: 05/09/2013, 15:28

... that platelet L-arginine transport mainly Fig L-Arginine uptake in the presence or absence of Na+ in the external medium L-Arginine uptake was measured in washed platelets (2.0 · 108 platelets) ... Characterization of the L-arginine/ nitric oxide pathway in human platelets Br J Pharmacol 101, 325–328 Radomski, M.W., Palmer, R.M & Moncada, S (1990) An L-arginin...

Ngày tải lên: 08/03/2014, 02:20

... 1984] Improving protein nutrition is the second strategy for increasing production in ruminants with a high protein requirements These include young animals following weaning, cows in the last ... weight The potential for ruminant production to be increased from poor quality forages is of the order of 5-10 fold without any increase in the demand for forage To attain su...

Ngày tải lên: 08/03/2014, 23:20

... against Goat Pox (1 ml intra-muscular injection) in April and October 46 47 Chapter Training and information dissemination supporting improved goat productivity in Vietnam Introduction Training ... developing and implementing new appropriate technologies for improving goat production and increasing small-holder income in the south-east region of Vietnam The south-eas...

Ngày tải lên: 21/06/2014, 06:20