Hydrogen sulfide, a cardioprotective agent in ischemic heart

... the accumulation of metabolites and inorganic phosphate With a substantial decline in ATP, the Na+, K+-ATPase is inhibited, resulting in a further decline of K+ and an increase in Na+ Intracellular ... stress, and cell adherence They function in a three-tier module comprising of a MAPK kinase kinase, a MAPK kinase and a MAPK The mammalian MAPK can be subdivided into five f...

Ngày tải lên: 14/09/2015, 14:05

... established as a novel mediator of inflammation It has been demonstrated to play a pro-inflammatory role in animal models of local and systemic inflammation, including carrageenan-induced hindpaw ... 3-mercaptopyruvate sulfurtransferase AC adenylyl cyclase AECOPD Acute exarcebation of chronic obsructive pulmonary disease ALI Acute lung injury ALT Alanine aminotransferase ANOV...

Ngày tải lên: 10/09/2015, 08:32

... associated with accidents in the sewer and mining industry The gas is not only soluble in water, but also in petroleum H2S inhibits enzymes in mitochondria by binding with Fe3+ of cytochrome oxidase ... を中心に】神経中毒　硫化水素中毒 Clinical Neuroscience 2009, 27(8):894-896 doi:10.1186/1745-6673-5-28 Cite this article as: Morii et al.: Japanese experience of hydrogen...

Ngày tải lên: 20/06/2014, 00:20

... Coronary angiography, percutaneuous coronary intervention, quantification of Restenosis Selective coronary angiography was performed following the administration of intracoronary glyceryl nitrate At ... circumflex coronary artery; RCA: Right coronary artery; PCI: Percutaneous coronary intervention; PTCA: Percutaneous transluminal coronary angioplasty; AHI: Apnea...

Ngày tải lên: 12/08/2014, 15:21

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Ngày tải lên: 12/09/2015, 08:16

... less useful for treating chronic myocardial ischemia 1 .2. 2.3 .2 Intracoronary Artery Infusion Intracoronary injection allows homogeneous homing of cells into areas bordering the infarction zone It ... Suzuki et al 20 01 Species Sheep Rat Suzuki et al 20 01 Rat Jain et al 20 01 Rat Gulbins et al 20 02 Dib et al 20 02 Ghostine et al 20 02 30 days Rat Ligation Autologous SkMs Zhong...

Ngày tải lên: 12/09/2015, 08:16

... and Akt in both LN-229 and A1 72 human glioblastoma cell lines GDNF was however found to reduce the background activation of JNK and the A1 72 human glioblastoma cell line in a timedependent fashion ... potentiate adjuvant therapy It is likely that the chemoresistance properties are potentiated by autocrine and paracrine pathways and facilitated by mit...

Ngày tải lên: 14/09/2015, 12:13

... value in the group of myocytes subjected to ischemia/ reperfusion injury 30    3.2 NaHS induced cardioprotection via regulation of intracellular pH 3.2.1 Effect of NaHS on pHi in the rat ventricular ... the cell viability of cardiac myocytes subjected to ischemia (30 min) /reperfusion (10 min) C, group data show the protective effects of NaHS against the cardiac my...

Ngày tải lên: 02/10/2015, 17:13

... Summary Ischemic heart disease is the leading cause of death in the western society and a major health problem in developing countries In the current study, the role of hydrogen sulfide (H2S) in the ... blood flow into and out of the heart A region of the heart called the sinoatrial (SA) node is capable of producing and discharging an acti...

Ngày tải lên: 11/09/2015, 09:57

... article as: Derwall et al.: Administration of hydrogen sulfide via extracorporeal membrane lung ventilation in sheep with partial cardiopulmonary bypass perfusion: a proof of concept study on metabolic ... [31] Inhibitory effects of H2S in the presence of increased metabolism in larger mammals warrants further study Page of 10 Our resu...

Ngày tải lên: 14/08/2014, 07:21

... inflammation and wound recovery after PAG administration (3) Compare the H2S releasing profiles and outcomes of S-diclofenac administration and PAG incorporated hydrogel dressing on wound healing ... microplate reader (Tecan Systems Inc.) All standards and samples were assayed in duplicate The H2S concentration of each sample was calculated according to a standard cu...

Ngày tải lên: 26/09/2015, 09:39

... NSW, Australia) Data was analyzed using PowerChrom (eDAQ, Australia) 2.15 Statistical analysis Statistical significance was assessed with one-way analysis of variance (ANOVA) followed by a post ... potential application of ADT as an H2S-releasing agent for disease treatments It was speculated that the combination of L-Dopa and H2S may have potential therapeutic value [233, 234] AC...

Ngày tải lên: 12/10/2015, 17:36

... precision of therapy like the intensity-modulated radiation therapy (IMRT) and the use of heavy ions demands absolute reliability of new diagnostics and treatment planning for prostate and brain ... 14 It was used to investigate whether an intracellular MR imaging is possible and to estimate the T1 relaxivity on MR (1.5 T) Historically already in 1994 electron-spin-resonance...

Ngày tải lên: 26/10/2012, 09:07