X ray crystallographic study of yeast dcp1 and dcp2 proteins insights into the mechanism and regulation of eukaryotic mRNA decapping

X ray crystallographic study of yeast dcp1 and dcp2 proteins insights into the mechanism and regulation of eukaryotic mRNA decapping

X ray crystallographic study of yeast dcp1 and dcp2 proteins insights into the mechanism and regulation of eukaryotic mRNA decapping

... out by the Dcp1- Dcp2 holoenzyme Dcp2 is a Nudix pyrophosphatase and Dcp1 stimulates the activity of Dcp2 The crystal structures of yeast Dcp1 and Dcp2 proteins are presented in this study The structure ... function and regulation of the decapping proteins Dcp1 and Dcp2 Yet several questions still remain open regarding the decapping com...

Ngày tải lên: 14/09/2015, 12:28

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Tài liệu Báo cáo khoa học: X-ray crystallographic and NMR studies of pantothenate synthetase provide insights into the mechanism of homotropic inhibition by pantoate docx

Tài liệu Báo cáo khoa học: X-ray crystallographic and NMR studies of pantothenate synthetase provide insights into the mechanism of homotropic inhibition by pantoate docx

... robust synthesis of pantothenate from low amounts of pantoate [9] Here, we report the results of the structural studies of the pantoate- bound form of the N-terminal domain of E coli PS (nPS) The structure ... [13] Details of the structural basis for the biochemically observed inhibition of plant PS by pantoate, as well as of the alleviation of...

Ngày tải lên: 16/02/2014, 09:20

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High resolution x ray diffraction study of phase and domain structures and thermally induced phase transformations in PZN (4 5 9)%PT 2

High resolution x ray diffraction study of phase and domain structures and thermally induced phase transformations in PZN (4 5 9)%PT 2

... surface X- ray 44.65o ~43.0-44.0o 42 43 44 45 46 47 2 [010]W [100] L PZN- 4 .5% PT b) b) Fractured surface Intensity (arb units) X- ray X- ray 44. 62 42 43 44 45 o 46 47 2 Figure 5. 1 (0 02) XRD profiles of ... 44.94 ~43 .5- 44.8 42 43 o o 44 45 2 Figure 5. 4 Intensity (arb units) e) PZN- 9%PT Intensity (arb units) 45 2 2 46 47 42 44 .50 o 44.94o 44 .28 o 43 44 45...

Ngày tải lên: 14/09/2015, 08:40

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High resolution x ray diffraction study of phase and domain structures and thermally induced phase transformations in PZN (4 5 9)%PT 3

High resolution x ray diffraction study of phase and domain structures and thermally induced phase transformations in PZN (4 5 9)%PT 3

... consisted of highly distorted R phase owing to the soft elastic constants of R The distorted R phases are microscopic in size, of a wide range of lattice parameters and are stressed in intense ... to the poling treatment 5. 4 (a) Summary of main observations The cause for the occurrence of the extremely broad lower 2θ peak adjacent to the main (002)R peak in standard XR...

Ngày tải lên: 14/09/2015, 08:40

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High resolution x ray diffraction study of phase and domain structures and thermally induced phase transformations in PZN (4 5 9)%PT 4

High resolution x ray diffraction study of phase and domain structures and thermally induced phase transformations in PZN (4 5 9)%PT 4

... annealing at 600 °C for h and the position shifted further to 2θ ≈ 44 . 05 (Figure 5. 9) 69 as-polished 300oC (1h) ~44 .68 o R Intensity (arb units) 40 0oC (1h) 600oC (5h) ~44 . 05 ~43 .50 41 42 43 ... annealing treatments The heating and cooling rates used were 1 .5 ºC/min Figure 5. 9 shows the (002) XRD profiles of the differently annealed PZN- 4 .5% PT samples and the (...

Ngày tải lên: 14/09/2015, 08:40

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High resolution x ray diffraction study of phase and domain structures and thermally induced phase transformations in PZN (4 5 9)%PT 5

High resolution x ray diffraction study of phase and domain structures and thermally induced phase transformations in PZN (4 5 9)%PT 5

... RSM To explain how domain size may affect the (002) diffraction profiles, we begin with diffractions arising from untilted T microdomains By microscale domains, we mean here coarse domains of which ... micro/nanodomains T5 T6 T ω = 0° Figure 6.2 (002) diffraction intensity weighted distributions arising from (a) T microdomains, (b) interference effect of T nanodomains and (c) comb...

Ngày tải lên: 14/09/2015, 08:40

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High resolution x ray diffraction study of phase and domain structures and thermally induced phase transformations in PZN (4 5 9)%PT 6

High resolution x ray diffraction study of phase and domain structures and thermally induced phase transformations in PZN (4 5 9)%PT 6

... projection of the coexistence of R micro- and nanotwins onto (002) RSM 112 coexistence of R micro- and nanotwin domains on (002) RSM 7.3 Evidence of rhombohedral micro/nanotwins in PZN- 4 .5% PT at ... domains, a result of the large diffraction width associated with the fine domain structure and the extreme compliant nature of the R phase The diffraction pattern i...

Ngày tải lên: 14/09/2015, 08:40

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High resolution x ray diffraction study of phase and domain structures and thermally induced phase transformations in PZN (4 5 9)%PT 7

High resolution x ray diffraction study of phase and domain structures and thermally induced phase transformations in PZN (4 5 9)%PT 7

... and (b) PZN- 7% PT, and (c) and (d) PZN- 8%PT single crystals 1 27 sample of PZN- 7% PT and PZN- 8%PT, respectively, but of the same wafers as in Figures 8.1(a) and (c) These peaks lie in two different ... Ruling out both MB and MC phases being the viable phase, the peak(s) at 2θ ≈ 44-90- 45. 0° must arise from the (100)T domains We may thus conclude that “LT” pha...

Ngày tải lên: 14/09/2015, 08:40

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High resolution x ray diffraction study of phase and domain structures and thermally induced phase transformations in PZN (4 5 9)%PT 8

High resolution x ray diffraction study of phase and domain structures and thermally induced phase transformations in PZN (4 5 9)%PT 8

... (b) 85 ºC P/A= 0º P/A= 45 (c) 1 05 ºC P/A= 0º P/A= 45 (d) 1 45 ºC P/A= 0º P/A= 45 (e) 1 65 ºC P/A= 0º P/A= 45 (f) 1 68 ºC C P/A= 45 T C T P/A= 45 [100] 200 µm [010] Figure 8. 11 ZFH domain structures ... of (001)T twin diffractions in as-grown PZN- 6%PT single crystal may be due to the higher residual stress and/ or the presence of a much higher portion of T nanotwin domai...

Ngày tải lên: 14/09/2015, 08:40

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High resolution x ray diffraction study of phase and domain structures and thermally induced phase transformations in PZN (4 5 9)%PT 9

High resolution x ray diffraction study of phase and domain structures and thermally induced phase transformations in PZN (4 5 9)%PT 9

... of the depolarization and R-T phase transformation events in poled PZN- PT single crystals PZN- 4 .5% PT and PZN- 7%PT single crystals, of [100]L×[010]W×[001]T in orientation and 6L×2W×0.35T mm3 in ... tilting of the R diffraction out of the ω = 0° plane indicates that both crystals existed in a strained state as the result of poling induced stresses This find...

Ngày tải lên: 14/09/2015, 08:40

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High resolution x ray diffraction study of phase and domain structures and thermally induced phase transformations in PZN (4 5 9)%PT 10

High resolution x ray diffraction study of phase and domain structures and thermally induced phase transformations in PZN (4 5 9)%PT 10

... emergence of R-T phase transformation in PZN- PT single crystals, giving TR-T(L) ≅ TDP ≅1 05- 110 °C for PZN- 4 .5% PT and ≅90 -100 °C for PZN- 7%PT These results, including the upper bound values of TR-T, ... (b) 110 ºC, and (c) 1 15 ºC The intensity contours are in log scale T# indicates the vague T diffractions TNT denotes the T at ∆ω ≠ 0º 172 o ε' (x1 0 ) (a) 100 C ε'...

Ngày tải lên: 14/09/2015, 08:40

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High resolution x ray diffraction study of phase and domain structures and thermally induced phase transformations in PZN (4 5 9)%PT 11

High resolution x ray diffraction study of phase and domain structures and thermally induced phase transformations in PZN (4 5 9)%PT 11

... crystal domains in single crystal relaxor ferroelectric, J Appl Phys., 87, p 8 159 -8164 2000 70 Yin, J and W Cao Domain configurations in domain engineered 0. 955 Pb(Zn1/3Nb2/3)O3-0.045PbTiO3 single crystals ... (001)T domains in PZN( 6-8)%PT crystals, which are shadowed by the R domains upon fracturing (b) To investigate the effects of temperature and E-field on the R and...

Ngày tải lên: 14/09/2015, 08:40

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Báo cáo khoa học: An X-ray diffraction study of model membrane raft structures doc

Báo cáo khoa học: An X-ray diffraction study of model membrane raft structures doc

... FEBS 4693 Membrane raft structure P J Quinn and C Wolf Fig Cartoons of the molecular composition of the different structures proposed for the lipid matrix model of membrane raft structure and their ... remodelling of lipid anchors is a recognized process in raft function [40,41] suggests that the configuration of the raft anchors is a likely candidate The lipid matrix...

Ngày tải lên: 15/03/2014, 23:20

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Insights into the mechanism of safingol and its potential to synergize with anti cancer drugs

Insights into the mechanism of safingol and its potential to synergize with anti cancer drugs

... unknown The research presented in this thesis focused on elucidating the mechanism of safingol and its potential to synergize with conventional anti- cancer drugs The results presented in Chapter demonstrated ... (OMM) This leads to the release of cytochrome c (Cyt c) from inner mitochondrial membrane space into the cytosol Another pro-apoptotic protein,...

Ngày tải lên: 11/09/2015, 10:02

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