Role of CC3 in colorectal cancer progression
Role of CC3 in colorectal cancer progression
... the Tumor Colorectal Samples 3.6 Expression profile of CC3 in colorectal cell lines 3.7 Over-expression of CC3 in HCT116 and Colo320 colon cancer cell lines 3.8 Over-expression of CC3 in Colo320 ... alteration In animals, methylcytosine is mainly found in cytosine-guanine (CpG) 19 dinuleotides(Bird 1986) The presence of 5-methylcytosine in the promoter of spe...
Role of stathmin 1 in colorectal cancer metastasis and chemo resistance
... 11 3 6 .1. 4 Mutagenesis 11 3 6 .1. 5 6.2 HCT 116 and E1 cell lines 11 2 Transfection 11 4 Cell-based assays 11 5 6.2 .1 6.2.2 Wound healing 11 5 6.2.3 ... Stathmin- 1 1. 2 .1 The Stathmin family 1. 2.2 STMN1 in microtubule regulation 10 1. 2.3 STMN1 in cell cycle regulation 12 1. 2.4 STMN1 in cancer 14 ... Conclusion and future work 10 7 Chapter Materials...
Báo cáo khoa học: The in vitro effects of CRE-decoy oligonucleotides in combination with conventional chemotherapy in colorectal cancer cell lines potx
... particular phase of the cell cycle, and was associated with an increase in the sub-G1 (apoptotic) portion of the cell cycle We next investigated the effect of combining CDO with the chemotherapeutic ... possible model of drug interaction in GEO cells, which involves the complex interaction of proteins involved in cell cycle regulation To recapitulate, com...
báo cáo hóa học:" Enhancing the efficacy of cisplatin in ovarian cancer treatment – could arsenic have a role" potx
... Chemotherapy The most active chemotherapy agents in ovarian cancer are the platinum analogues, cisplatin and carboplatin The antitumor activity of cisplatin (cis-diamminedichloroplatinum (II)) was ... platinum-sensitive human ovarian cancer cell line OVCAR They also appeared to slow the growth of the cisplatin- sensitive human ovarian cancer cells GG and JAM [...
báo cáo hóa học:" Emerging role of microRNAs in diagnosis and treatment of various diseases including ovarian cancer" pdf
... deletion or loss -of- function mutations in the survival of motor neuron (SMN) protein results in SMA [12] Gemin and Gemin are shared components of SMN and miRNAcontaining ribonucleoprotein particles ... overexpression of miR-375 resulted in suppressed glucose-stimulated insulin secretion and its inhibition resulted in enhanced insulin secretion Myotrophin, a protein that...
báo cáo hóa học:" Role of CA125 in predicting ovarian cancer survival - a review of the epidemiological literature" pptx
... survival estimation of female patients with relapsed ovarian carcinoma In multivariate analysis only the variation of blood levels of CA125 and the free disease interval from the finalization of the ... CA125 Area under the Curve (AUC) and Ovarian Cancer Survival A study evaluated the usefulness of CA125 normalized in time area under the curve (CA...
báo cáo khoa học: "T cell subpopulations in lymph nodes may not be predictive of patient outcome in colorectal cancer" pps
... although analyses of T cell subsets in the lymph nodes of breast cancer patients have been performed [20], the effect of these T cell subsets on colorectal cancer patient outcome had not been explored ... were included in this study Stage II patients were chosen because they have no tumour metastases in lymph nodes The number of lymph nodes retrieved from...
Identification of a new tumor suppressor pathway modulating rapamycin sensitivity in colorectal cancer
... 3' ATGGAGGAGGACATTGATACC 3' ACATTGTATTCACCCCTACG 3' ATACGCCAGTGACGACCAGAGC 3' TAGCCCACACCATGAAAGCG 3' ATGGGAAGGTGAAGGTCGG 3' AAGACGCCAGTGGACTCCACGA 3' GTGGGGCGCCCCAGGCACCA 3' CTCCTTAATGTCACGCACGATTTC ... 3' AGTGGGCTGCGCGTCTCATTTTC 3' AAGGGTTCGTGGAGCATGGG 3' ATGGTTGCAACTGGCAGTTTG 3' AGGACCTTTGAGCAACCAAG 3' AACGGCAGCGCCTTCTTGCT 3' GGCCCATGACCAGATCAGCA 3' ATGAGCTGCACCAGAATGATCC 3' TTGGTTGTGTGAGC...
Heregulin enhanced tyrosine phosphorylation in breast cancer cells role of PP2A in HER 2 eu oncogenic signalling
... 44 2. 1 2. 1.1 2. 1 .2 2.1.3 2. 1.4 Materials Ligand and inhibitors Antibodies Cell-lines Fresh frozen clinical specimens 44 44 44 45 45 2. 2 2. 2.1 2. 2 .2 2 .2. 3 2. 2.4 2. 2.5 2. 2.6 2. 2.7 2. 2.8 2. 2.9 2. 2.10 ... REGULATION OF PP2A BY HER- 2/ neu 77 4.1 77 Overview 4 .2 4 .2. 1 4 .2. 2 4 .2. 3 4 .2. 4 Results 80 Inhibition of HER- 2/ neu signalling using AG...
The role of TFF3 in cytotoxic drug resistance of breast cancer
... function in normal tissues 31 1.5.2 TFF1 32 1.5.3 TFF3 34 1.5.3.1 TFF3 in cancer 35 1.5.3.2 TFF3 in breast cancer 36 1.5.3.3 The role of TFF3 in drug resistance of cancer 37 treatment 1.6 Aims of this ... 1.5.3.3 The role of TFF3 in drug resistance of cancer treatment Besides the role in development and progression of multiple ca...
Clinical reference of tumour infiltrating lymphocytes in colorectal cancer
... REFERENCES 67 iv SUMMARY Background: Approximately 10-30% of colorectal cancers are characterized with distinctly high densities of tumour- infiltrating lymphocytes (TILS), including ... affect the clinical phenotype of tumours Indeed, one of the most reproducible findings in prognostic studies has been that a high density of tumourinfiltrating lymphocytes (TILS) is ass...
ELUCIDATING THE ROLE OF AUTOPHAGY IN ZEBRAFISH MODELS OF LIVER CANCER
... transgenic line Establishing the role of autophagy in liver cancer 4.1 Preliminary data implicating autophagy inhibition in liver cancer 4.2 Establishing double transgenic lines with liver- specific ... as a model organism in the study of human diseases including cancers, we aim to investigate the role of autophagy in liver cancer using our establish...
Circuit theory of finance and the role of incentives in financial sector reform
... illustrates the main structural, theoretical and incentive-related policy implications of circuit theory of finance Section I.2 discusses the special role of the financial system as the core of the circuit ... profitability is declining The internalization of information within the same institution may thus enhance intra -circuit and inter -circuit st...
The role of language in adult education and poverty reduction in Botswan
... program in Botswana maintains the hegemony and the gap between the poor and the rich, the major and minority groups In order to redress poverty the adult education program needs to be aware of the social ... vital in fighting poverty The adult education program can thus harness the local languages and indigenous knowledge of the minority and...
The role of advertising in society
... categories of business-to-business advertising are industrial and professional advertising b.1 Industrial advertising Advertising targeted at individuals who buy or influence the purchase of industrial ... Index Introduction Part I : General knowledge of advertising Some typical concepts of advertising Classifications of advertising Part II : The role of adverti...
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