P125, a COPII INTERACTING PROTEIN 4
P125, a COPII INTERACTING PROTEIN 4
... of the COPII coat can link to the inner layer (Bi et al., 2007) As p12 5A can bind to both Sec2 3A (Tani et al., 1999; Nakajima et al., 2002; Shimoi et al., 2005) and Sec3 1A, and have the ability ... p12 5A or KIAA0310p also did not induce a similar effect on the ERES Depletion of KIAA0310p abolished almost all the punctate staining of ERES markers (Watson et al., 2006; Bhattacharyya...
Ngày tải lên: 14/09/2015, 08:42
P125, a COPII INTERACTING PROTEIN 1
... Sar1p (Gimeno et al., 19 95; SaitoNakano and Nakano, 2000) 1. 7 The COPII subunit proteins 1. 7 .1 Sar1- the small GTPase Sar1 (supressor of activated ras1) is a small G -protein of the Ras superfamily ... loading with GTP, Sar1 (Sar1-GTP) is activated and is recruited to the ER membranes (Nakano and Muramatsu, 19 89) Sar1 activation is facilitated by Sec12, an ER-resident guanine n...
Ngày tải lên: 14/09/2015, 08:42
P125, a COPII INTERACTING PROTEIN 2
... 5’-GACAGCGGCCGCTTCAATTCAAATCTTTTTGATTAGACAG-3’ p 12 5A- 650-R 5’-CAAGGCGGCCGCTTCACTGCTTCACAACTCCATTAGCAAC-3’ p 12 5A- 20 0-F 5’-CGGAGAGTCGACCCTGCAGCAGTGCCAAACACCAGGC-3’ p 12 5A- 26 0-F 5’-GTCCGAGTCGACCCTACTTCAAAACCAATATGAGCCTG-3’ p 12 5A- CT100-F ... TCGAGAAAAAGGAACATCTGCTCAGCAATTCTCTTGAAATTGCTGAGCAGATGTTCCGGG -3’ p 12 5A- PSRP-F 5’- GATCCCCGTTGACCATTTGGTGTTTGTTCAAGAGACAAACACCAAATGGTCA...
Ngày tải lên: 14/09/2015, 08:42
P125, a COPII INTERACTING PROTEIN 3
... co-immunoprecipitate Sec3 1A and vice versa However, both the available anti-Sec3 1A and anti-p12 5A antibodies 56 Thyroglobulin 669 kDa Apoferritin 4 43 kDa 150 kDa WB : Sec3 1A 150 kDa 100 kDa WB : p12 5A 75 kDa WB ... Sec 13 siRNA Bar = 10 μM p12 5A B Non-target siRNA Se ec3 1A siRNA Non-target siRNA Sec 13 siRNA A 83 84 Sec3 1A siRNA A p12 5A siRN NA Non-Target siRNA GT-G...
Ngày tải lên: 14/09/2015, 08:42
P125, a COPII INTERACTING PROTEIN 5
... the phagophore, and is required for the formation of autophagosomes (Nagatogawa et al., 2007) Atg8-PE is postulated to be a scaffold protein that supports membrane expansion and also have functions ... regulate p12 5A s protein interactions and stability of interactions in a metal ion dependent manner similar to ALG-2 5. 3 The Sterile Alpha Motif The SAM (Sterile Alpha Motif) domain...
Ngày tải lên: 14/09/2015, 08:42
P125, a COPII INTERACTING PROTEIN 6
... 71 Iinuma, T., Aoki, T., Arasaki, K., Hirose, H., Yamamoto, A. , Samata, R., Hauri, H.P., Arimitsu, N., Tagaya, M., and Tani, K (2009) Role of syntaxin 18 in the organization of endoplasmic reticulum ... subdomains J Cell Sci 122, 168 0- 169 0 72 Iinuma, T., Shiga, A. , Nakamoto, K., O'Brien, M.B., Aridor, M., Arimitsu, N., Tagaya, M., and Tani, K (2007) Mammalian Sec 16/ p250 plays a rol...
Ngày tải lên: 14/09/2015, 08:42
Isolation and characterization of aurora a kinase interacting protein (AKIP), a novel negative regulator for aurora a kinase
... Hypothesis of Possible Anti-Tumour Role of AKIP-mediated UbIndependent Degradation of Aurora- A, 234 ix Abbrevations aa A Box AD ADH AIK1 AKIP ALLM ALLN AML Amp APC/C ATP AURKA AZ AZI amino acid Aurora ... yeast and successfully isolated a novel negative regulator of Aurora- A kinase, named as AKIP (Aurora- A Kinase Interacting Protein) AKIP is an ubiquitous...
Ngày tải lên: 14/09/2015, 22:15
Identification and characterization of protein kinase CK2 as a novel interacting protein of neuronal CDK5 kinase and its functional role in microtubule dynamics
... acidic proteins (Hathaway and Traugh, 1982) Two distinct casein kinases have been found in many different cell types They have been designated casein kinase (CK1) and casein kinase (CK2) according ... Ca2+/calmodulin-dependent protein kinase II cAMP cyclic adenosine monophosphate Cdk cyclin-dependent kinase Cdk5 cyclin-dependent kinase cDNA complementary deoxyribonucleic a...
Ngày tải lên: 16/09/2015, 17:10
Tài liệu Báo cáo khoa học: The Arabidopsis protein kinase Pto-interacting 1-4 is a common target of the oxidative signal-inducible 1 and mitogen-activated protein kinases docx
... GCTCAGTGGTGGA-3 and 5-CTGAGGGAAGCAAG AATGGA-3, OXI1 (At3g25250): 5-GACGAGATTATC AGATTTTACGC-3 and 5-AACTGGTGAAGCGGAAG AGAC-3, PTI1-4 (At2g47060): 5-CCCCAAAGAAAATG AGTTGCT-3 and 5-GCATCATTTCCTGGAGGAAAG-3 ... Journal 278 (2 011 ) 11 26 11 36 ª 2 011 The Authors Journal compilation ª 2 011 FEBS 11 31 PTI1-4, a common target of OXI1 and MAPKs C Forzani et al AGC2-3) were also...
Ngày tải lên: 14/02/2014, 19:20
Tài liệu Báo cáo khoa học: Crystal structure of importin-a bound to a peptide bearing the nuclear localisation signal from chloride intracellular channel protein 4 ppt
... A2 for main-chain atoms, 35.7 A2 for side-chain ˚ overall (3 244 atoms) For the pepatoms and 33.8 A tide, B factors are slightly higher than those for ˚ ˚ importin -a: 36.9 A2 for main-chain atoms, ... atoms, 40 .2 A2 for ˚ overall (62 total atoms) side-chain atoms and 38.7 A Electron density analysis Both the main-chain and side-chain atoms of the modelled CLIC4 peptide...
Ngày tải lên: 14/02/2014, 19:20
Báo cáo khoa học: Interactions of HIPPI, a molecular partner of Huntingtin interacting protein HIP1, with the specific motif present at the putative promoter sequence of the caspase-1, caspase-8 and caspase-10 genes pdf
... Allowing two substitutions Allowing two substitutions Allowing one substitution AAAGACATG AAAGACAGG AAAGAGATT AAAGAGATG AAAGACATA AAAGACATA AAAGAGAAC AAAGACATA AAAGAAAAG AAACAGATG AAAGAAAAG AAAGAAAAG ... EMSA Result Average Kd (nM) AAAGACATG AGAGACATG AAGGACATG AAATACATG AAAGCCATG AAAGAGATG AAAGACCTG AAAGACACG AAAGACATA + ND ND – – + ND ND ND + – – – – + – + – 0.25 1.5 p=0.01 60_HI 60M_HI Fig...
Ngày tải lên: 07/03/2014, 10:20
Báo cáo khoa học: A role of monocyte chemoattractant protein-4 (MCP-4)/CCL13 from chondrocytes in rheumatoid arthritis doc
... Hamid QA (1999) Eotaxin and monocyte chemotactic protein-4 mRNA expression in small airways of asthmatic and nonasthmatic individuals J Allergy Clin Immunol 103 (3 Part 1), 476–483 Taha RA, Minshall ... new target for anti-RA therapy Experimental procedures Preparation of articular cartilage and synovial tissue Human articular cartilage and synovial tissue were obtained from OA an...
Ngày tải lên: 16/03/2014, 05:20
Báo cáo khoa học: Brox, a novel farnesylated Bro1 domain-containing protein that associates with charged multivesicular body protein 4 (CHMP4) potx
... has a point mutation at amino acid 40 8, was created by PCR-based site-directed mutagenesis using pmGFP–Brox as a template and complementary primers (5¢-CAA AAG GAC ACT GGG TCC TAC ATC TCC TAA ... AAT TCA TGA CCC ATT GGT TTC ATA GGA ACC-3¢ and 5¢-GGG AAT TCT TAG GAG ATG TAG CAC CCA GTG TC-3¢ (nucleotides corresponding to a cDNA of the hypothetical protein C1orf58 are underlined), and...
Ngày tải lên: 16/03/2014, 06:20
Báo cáo khoa học: The proapoptotic member of the Bcl-2 family Bcl-2 / E1B-19K-interacting protein 3 is a mediator of caspase-independent neuronal death in excitotoxicity pot
... protein (BNIP3) is a member of a unique subfamily of death- inducing mitochondrial proteins [14,15] BNIP3-induced cell death has been characterized by early plasma membrane and mitochondrial damage ... glutamate-induced excitotoxicity BNIP3 is a BH3-only proapoptotic member of the Bcl-2 family However, unlike in other members of the Bcl-2 family, t...
Ngày tải lên: 22/03/2014, 17:20
giáo án tham khảo bồi dưỡng thao giảng, thi giáo viên giỏi sinh học lớp 9 bài protein (4)
Ngày tải lên: 31/10/2014, 11:26