Development of direct asymmetric aldol reactions mediated by primary amino acid derived organocatalysts exploring DNA cleaving activities of varacin b and varacin c

... PART Ⅰ: DEVELOPMENT < /b> OF < /b> DIRECT < /b> ASYMMETRIC < /b> ALDOL < /b> REACTIONS < /b> MEDIATED < /b> BY < /b> PRIMARY < /b> AMINO < /b> ACID-< /b> DERIVED < /b> ORGANOCATALYSTS < /b> PART Ⅱ: EXPLORING < /b> DNA-< /b> CLEAVING < /b> ACTIVITIES < /b> OF < /b> VARACIN < /b> B AND VARACIN < /b> C JIANG ZHAOQIN ... 2-hydroxy-γ-butyrolactones 150 Scheme 5-1 Structur...

Ngày tải lên: 14/09/2015, 08:39

... Direct Asymmetric Vinylogous Reactions of Furanones and Phthalide Derivatives with Bifunctional and Trifunctional Organocatalysts Luo Jie (BSc, Zhejiang ... development of direct enantioselective vinylogous reaction of furanones and phthalide derivatives with bifunctional and trifunctional organocatalysis Chapter presents a brief historical...

Ngày tải lên: 10/09/2015, 08:24

... arrangement by the influence of amino acids C266 and L268 These residues face the other side of this tyrosine and are members of a conserved loop (266CGLKG270) that shapes part of the FNR catalytic site ... interaction between the flavin, Y308 and the nicotinamide of NADP+ is precisely tuned by selecting amino acids that face the other side of the tyrosine...

Ngày tải lên: 18/02/2014, 17:20

... evaluate the therapeutic potential of expression vectors carrying the "A" fragment of the diphtheria toxin (DT -A) gene under the control of the H19 regulatory sequences in an ovarian carcinoma ... expression profiling allows an individualized DNA-base approach to cancer therapy The therapeutic potential of the DTA -H19 vector was tested in a rat ani...

Ngày tải lên: 18/06/2014, 15:20

... an approach for targeted therapy of bladder carcinoma by driving the DTA expression under the control of IGF2-P4 and H19 regulatory sequences To evaluate the possible use of IGF2-P4 and H19 regulatory ... therapy is an attractive approach Based on early studies of our group and others, the transcriptional regulatory sequences of the H19...

Ngày tải lên: 18/06/2014, 16:20

... the direct effect of adaptive abilities on health state utilities without controlling for mental health, and finally we checked if after controlling for mental health the direct effect of adaptive ... compensations for adaptation can be made List of abbreviations CAT: Cognitive Adaptation Theory; HRQL: Health Related Quality of Life; SF36: MCS Short-Form 36 Mental...

Ngày tải lên: 20/06/2014, 15:20

... ANTI- TUMOR PROPERTIES OF LACTOBACILLI ARE MEDIATED BY IMMUNO- MODULATION AND DIRECT CYTOTOXICITY CAI SHIRONG B.Sc (Hons), NUS A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY ... the anti- tumor properties of LGG and compare it with that of other lactobacillus strains The study is divided into main areas: I Immuno- modulation by lactobaci...

Ngày tải lên: 11/09/2015, 09:16

... method, which can transmit the view of forks’ environment in term of force feedback information, and we named it as observe-by-wire system The essential components of an OBW system are distance sensors ... Rossetter, Ian A Coe, J Christian Gerdes “Handwheel Force Feedback for Lanekeeping Assistance: Combined Dynamics and Stability,” American Society of Mechanical Engineers -...

Ngày tải lên: 17/12/2013, 11:15

... errors of seven subjects with OBW mode and without OBW mode From the research that has been carried out, we can conclude that: The concept of obsever -by- wire is given and a systematic study of observe- by- wire ... regardless to the height of masts, vehicle’s roof as well as intensity of illumination Therefore, the drive could also reduced risk of damaging the load and the war...

Ngày tải lên: 22/12/2013, 08:16

... method, which can transmit the view of forks’ environment in term of force feedback information, and we named it as observe-by-wire system The essential components of an OBW system are distance sensors ... Rossetter, Ian A Coe, J Christian Gerdes “Handwheel Force Feedback for Lanekeeping Assistance: Combined Dynamics and Stability,” American Society of Mechanical Engineers -...

Ngày tải lên: 23/12/2013, 00:15

... method, which can transmit the view of forks’ environment in term of force feedback information, and we named it as observe-by-wire system The essential components of an OBW system are distance sensors ... Rossetter, Ian A Coe, J Christian Gerdes “Handwheel Force Feedback for Lanekeeping Assistance: Combined Dynamics and Stability,” American Society of Mechanical Engineers -...

Ngày tải lên: 22/01/2014, 02:20

... purify CDK4 Y17 kinases from HeLa cell extracts, and found that the cellular phosphorylation of CDK4 on Y17 is mediated by Src family kinases Results Detection of CDK4 Y17 phosphorylation and kinase ... that Y17 phosphorylation is mediated by Src family kinases is completely novel and it is interesting to note how this fits in with the previously pub...

Ngày tải lên: 18/02/2014, 18:20

... tool for nations to regions in terms of developing climate change scenarios Developing climate change scenarios for small areas of Vietnam Based on software MAGICC / SCENGEN, we have built climate ... form of decades of the 21st century However, within the scope of this paper, we only introduce climate change scenarios that are summarized in...

Ngày tải lên: 05/03/2014, 16:20

... protons into the matrix, bypassing F0 F1-ATPsynthase [6] The dotted line shows the result of the modeling after estimation of the unknown parameters The con- Modeling of ANT ditions of the described ... novel kinetic assay of mitochondrial ATPADP exchange rate mediated by the ANT Biophys J 96, 24902504 Metelkin E, Goryanin I & Demin O (2006) Mathematical...

Ngày tải lên: 16/03/2014, 00:20