Investigations on the toxicity of nanoparticles

... + Oxidationm-n- 1.3 Equation 1.3 depends on the thermodynamics of the process, which in turn is represented by the electrochemical potentials of the corresponding half cell reactions These are ... stability of the particles Agglomeration of the nanoparticles will yield particles of size in the micron range, skewing data interpretation The commercially available...

Ngày tải lên: 14/09/2015, 08:26

Ngày tải lên: 09/09/2015, 10:19

... of EV 71 strains 18 4 CHAPTER CONCLUSION AND FUTURE WORK 19 2 7 .1 ROLE OF INTERLEUKIN-6 IN THE IMMUNOPATHOGENESIS OF EV 71 INFECTION 19 2 7.2 ROLE OF DC IN EV 71 INFECTION ... Distribution of EV 71 isolates identified globally from 19 70 to 2000 16 Figure 1. 4 Distribution of inflammation in brain sections of EV 71 patients 23 Figure 1. 5 The postulated pathol...

Ngày tải lên: 09/09/2015, 10:21

... percentage composition per spleen The dotted line indicates the highest amount or percentage of cells observed for the two fatal strains (B) Specific anti-EV71 IgM and IgG titers in sera of infected ... CHAPTER INVESTIGATIONS ON EV71 VIRULENT DETERMINANTS B Figure 6.5 Adaptive immune response in EV71-infected AG129 mice (A) Two-week-old mice were infected ... (n=5) were euthaniz...

Ngày tải lên: 09/09/2015, 10:21

... well as the effects of the systemic inflammatory response on the vascular endothelium The key to further decipher the exact mechanisms for PE in EV71 encephalitis relies on the development of more ... observed (Shieh et al, 20 01; Yang et al, 20 09) 22 CHAPTER LITERATURE REVIEW Figure 1.4 Distribution of inflammation in brain sections of EV71 patients (A) Whole brai...

Ngày tải lên: 09/09/2015, 10:21

... CHAPTER CONCLUSION One limitation of the present study is the use of neonatal mice as animal model IL-6 functions mainly as the inducer of acute-phase response and T- and B-cell stimulation Given the ... throughout the course of infection While we could not entirely rule out the contribution of myositis to EV71-induced disease manifestations, our results suggest that th...

Ngày tải lên: 09/09/2015, 10:22

... INVESTIGATIONS ON THE ROLES OF UBIQUITIN IN THE REGULATION OF HEAT SHOCK GENE HSP70B EE THIAM HEE, GARY NATIONAL UNIVERSITY OF SINGAPORE 2 011 INVESTIGATIONS ON THE ROLES OF UBIQUITIN IN THE ... THE REGULATION OF HEAT SHOCK GENE HSP70B EE THIAM HEE, GARY (B SCI (HONS), NUS A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY...

Ngày tải lên: 10/09/2015, 08:27

... regulation of transcription In this project we investigated the role of ubiquitin in the regulation of the heat shock gene HSP70B Through RNA interference of SKP1, a component of an ubiquitin ligase ... Role of Med21/hSrb7 in the Regulation of HSP70B 109 3.7 The Effect of the RNA Interference of Med21/hSrb7 and its Effects on Proteosomal...

Ngày tải lên: 10/09/2015, 08:27

... as the link between the methylation of histone H3 residues lysine 34 and lysine 79 (H3K34 and H3K79) and the ubiquitination of histone H2B, abrogating the methylation of H3 while leaving the ubiquitinated ... 2005) 1 .3. 4 E4 Ubiquitin Ligases in the Elongation of Polyubiquitin Chains While the E3 ubiquitin ligases mediate the initial ubiquitination of the s...

Ngày tải lên: 10/09/2015, 08:28

... composition of the Fe-Pt nanoparticles was controlled by adjusting the current density (corresponding to the applied voltage) When the current density of 15 – 20 mA/cm2, the composition of nanoparticles ... [21] The broad peak on the DSC trace in the FePt nanoparticles suggests that there was no such transition in the FePt nanoparticles upon annealing Th...

Ngày tải lên: 13/02/2014, 03:20

... removed by iron nanoparticals, while only 24.75% Cr(VI) concentration was removed by iron powder Conclusion The removal of Cr(VI) by Fe0 nanoparticles was studied, the concentration of Fe0 nanoparticles ... minutes, then slow down afterwards 3.5 Comparison of the effectiveness of Cr(VI) reduction by nanoiron and power iron Experimental conditions: pH = 4-5, C...

Ngày tải lên: 14/03/2014, 10:20

... surface and the consequent effect on the structure of the protein Towards achieving this goal we studied the effect of ZnO NPs on the structure of ToxRp, alone and in the presence of denaturing ... changes of the ToxRp protein of V cholerae Based on the thermodynamic parameters of binding one can speculate on the nature of the interact...

Ngày tải lên: 23/03/2014, 03:20

... vertebrates In conclusion, there is a single, large, evolutionarily conserved protrusion on the surface of the catalytic domain of PCSK9 The lack of other residue conservation on the PCSK9 surface ... of the mutants S15 3A -PCSK9, Q19 0A -PCSK9, R19 4A -PCSK9, D20 4A -PCSK9, K22 2A -PCSK9, R23 7A -PCSK9, D23 8A -PCSK9, D37 4A -PCSK9, C37 5A -PCSK9, S37...

Ngày tải lên: 23/03/2014, 07:20

... Q in the other microemulsion, upon mixing, they will form precipitate PQ, which will be contained entirely within the aqueous cores of the microemulsions The growth of these particles in microemulsions ... diffusion of solutes from the solution or/and aggregation of other nuclei to their surface until the final size was attained In conventional coprecipitation, size (d) c...

Ngày tải lên: 28/03/2014, 10:20

... Researches on the influence of Au on DSSC performance The application of Au in the DSSC has been used for three reasons The first application is that the Au nanoparticles dispersed into TiO2 porous film ... concentration of active Au nanoparticles An investigation into the cause of the damping of the photocurrent of Au/ TiO2 composite...

Ngày tải lên: 10/09/2015, 15:47