Characterization of adult human bone marrow mesenchymal stem cells for effective myocardial repair

... 1.5.2.1 Bone marrow stem cells There are most common types of stem cells in bone marrow: (i) hematopoietic stem cells and (ii) mesenchymal stem cells These cell types are believed to be ideal for myocardial ... Stem cells 1.5.1.1 Embryonic stem cells 1.5.1.2 ES cell stem therapy is not ideal for clinical use 1.5.2 Adult stem cells 10 1.5.2.1...

Ngày tải lên: 12/09/2015, 09:42

... intravenously injected into nude mice and the distribution and migration of MSCs were dynamically monitored to evaluate the feasibility and safety of intravenous implantation of allogeneic MSCs in the ... transplanted the bone marrow stem cells into the necrotic femoral heads, and results show bone marrow stem cells can remove vascular lesions...

Ngày tải lên: 25/10/2012, 11:18

... article as: Liu et al.: Effects of transplantation with bone marrow-derived mesenchymal stem cells modified by Survivin on experimental stroke in rats Journal of Translational Medicine 2011 9:105 Submit ... result in better therapeutic effects for stroke in rats In this paper, we try to investigate the effects of transplantation with MSCs mod...

Ngày tải lên: 18/06/2014, 19:20

... differentiation of MSCs: Upon induction with adipocyte induction media cells showed adipocyte globules on oil red O staining (D) Osteogenic differentiation of MSCs: Upon induction with osteogenic induction ... http://www.translational-medicine.com/content/9/1/105 Evaluation of neurological function Evaluation of neurological function was performed day and 14 days after transp...

Ngày tải lên: 20/06/2014, 04:20

... that marrow lipid was a consequence of the adipogenesis of marrow mesenchymal stem cells (MSCs) [7] Results of a previous study showed increased number of small size fat cells in the early steroid-associated ... association between the adipogenesis of MSCs and steroid-associated ON development during early stage A close association between elevated adipo...

Ngày tải lên: 20/06/2014, 00:20

... Sphingosine-1-phosphate promotes the differentiation of human umbilical cord mesenchymal stem cells into cardiomyocytes under the designated culturing conditions Journal of Biomedical Science 2011 ... have successfully produced both neonatal cardiac myocyte and cardiomyocytes sheets from differentiated human umbilical cord mesenchymal stem cells...

Ngày tải lên: 10/08/2014, 05:21

... this article as: Yang et al.: High efficient isolation and systematic identification of human adipose-derived mesenchymal stem cells Journal of Biomedical Science 2011 18:59 Submit your next manuscript ... differentiation of cryopreserved human adipose-derived stem cells Cryobiology 2008, 57:18-24 Chen MY, Lie PC, Li ZL, Wei X: Endothelial differentiation of...

Ngày tải lên: 10/08/2014, 10:20

... using the corresponding inhibitors They included 1-MT (1 mM), an inhibitor of IDO enzymatic activity, INDO (5 μM), an inhibitor of PGE2 synthesis, L-NAME (1 mM), a specific inhibitor of NO synthase, ... Notably, delayed addition of UC-MSCs maintained such inhibitory effects, suggesting that the transplantation of these cells is practicable and effective for treatment of RA...

Ngày tải lên: 12/08/2014, 15:22

... TRANSPLANTATION OF MESENCHYMAL STEM CELLS FOR THE TREATMENT OF PARKINSON’S DISEASE IN A MOUSE MODEL CHAO YIN XIA MD A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY DEPARTMENT OF ANATOMY ... MPTP, an acute insult initiates an inflammatory reaction that becomes self sustaining after the initiating agent has disappeared The MPTP model of...

Ngày tải lên: 11/09/2015, 09:05

... streptomycin (Invitrogen, Carlsbad, CA) in plastic flasks (25 cm2), and maintained in a humidified atmosphere of 5% CO2 in air at 37°C The culture medium used for expansion was initially changed ... hFTs lineage in passage two Panel B) Results of hFTs lineage in passage 11 We observed high rates of cell division, with gradual decreasing of the population doubling time (PDT...

Ngày tải lên: 18/06/2014, 15:20

... embryogenesis and morphogenesis of various tissues and organs, where they regulate growth, differentiation, chemotaxis and apoptosis of a variety of cell types, including mesenchymal, epithelial, ... compare the effects of BMP-4 and BMP-2 expression on chondrogenesis of primary MSCs and to investigate whether levels and extent of hypertrophy in vitro is influ...

Ngày tải lên: 09/08/2014, 14:22

... Dou KF, Yang GS, Willerson JT, Geng YJ: Combined therapy with simvastatin and bone marrow-derived mesenchymal stem cells increases benefits in infarcted swine hearts Arterioscler Thromb Vasc Biol ... neovascularization in murine hindlimb ischemia by combined therapy with simvastatin and bone marrow-derived mesenchymal stem cells transplan...

Ngày tải lên: 10/08/2014, 05:21

... Immunomodulatory properties of human adult and fetal multipotent mesenchymal stem cells Journal of Biomedical Science 2011 18:49 Submit your next manuscript to BioMed Central and take full advantage of: ... Shankar SR, Vasandan AB: Pro-inflammatory cytokines, IFNgamma and TNFalpha, influence immune properties of human bone marrow and Wharton jelly mesenchymal...

Ngày tải lên: 10/08/2014, 05:21

... Induction Upon Biaxial Bioreactor Stimulation of Mesenchymal Stem Cells and Endothelial Progenitor Cells Cocultures in 3D Honeycomb Scaffolds for Vascularised Bone Tissue Engineering Tissue Engineering ... success of the tissue engineering strategy (Figure 1- 1) Cells and Biomolecules Scaffolds TISSUE Bioreactors Imaging Tools Figure 1-...

Ngày tải lên: 09/09/2015, 10:16

... Types of cells used in bone tissue engineering for osteogenic differentiation 59 2.3.1 Potential of mesenchymal stem cells (MSCs) for bone healing 60 2.3.2 Potential of bone marrow derived mesenchymal ... Casey K Chan Effects of mechanical stimulation in osteogenic and chondrogenic differentiation of bone marrow- derived mesenchymal stem cells on...

Ngày tải lên: 11/09/2015, 09:57