Regulation of gene expression by esrrb in embryonic stem cells

... Chip-sequencing assay 3.4.2 Genome-wide mapping of Esrrb binding sites 3.4.3 Distribution of Esrrb binding and gene expression profiling 3.4.4 Functional relevance of the target genes 3.4.4.1 Esrrb binds ... phenotype induced by Esrrb depletion Thus, Nanog is a key downstream target of Esrrb in maintaining pluripotency In addition, Esrrb is involved in the reg...

Ngày tải lên: 12/09/2015, 08:19

... of this study was to gain more insight of the consequences of the BF intersubtype recombination phenomenon on the different but functionally related genomic regions LTR and Vpr/Tat, through the ... directly bind to p300 via interaction the C-terminal αhelix of the protein [29] suggesting that Vpr may act by recruiting them to the HIV-1 promoter thus enhancing v...

Ngày tải lên: 12/08/2014, 04:21

... of this study was to gain more insight of the consequences of the BF intersubtype recombination phenomenon on the different but functionally related genomic regions LTR and Vpr/Tat, through the ... directly bind to p300 via interaction the C-terminal αhelix of the protein [29] suggesting that Vpr may act by recruiting them to the HIV-1 promoter thus enhancing v...

Ngày tải lên: 12/08/2014, 04:22

... indications of immune activation emerged in the set of over-expressed genes, including proinflammatory cytokines, chemokines, granzymes, proteinases, and receptors for inflammatory mediators ... effects may be shaped by reduced activity of the anti-inflammatory glucocorticoid transcription control pathway and a complementary increase in activity of the pro-inflammatory NF-κB/ Rel...

Ngày tải lên: 14/08/2014, 08:20

... was the number of genes in Model CN-enhanced (the child list), k was the number of genes in the pathway being analyzed and in the child list, and p was the number of genes in the pathway being ... model includes genes not regulated by carbon, nitrogen and/ or CN The 'C-only' model includes genes regulated only by carbon Finally, the 'N-only' model incl...

Ngày tải lên: 14/08/2014, 14:21

... which could potentially modulate sense mRNA through two distinct modes of action One of the most exciting findings in genome biology in recent years has been the discovery of RNA interference (RNAi), ... Endogenous singlewell expression of( HIF) and its antisense antisense Figure Endogenous single cell expression of TS sense (TS) and its antisense (rTSα) mRNA, as well a...

Ngày tải lên: 14/08/2014, 16:21

... modulation of the transcription rates of all genes, accounting for the global regulation of gene expression [22] Gene- specific cis-regulatory elements that mediate rhythmic gene expression might therefore ... specific clock -gene promoters, suggests a broadly global mechanism for the cyanobacterial clock system But what is the basis of this global regulati...

Ngày tải lên: 09/08/2014, 20:20

... the regulation of translation of maternally inherited mRNA by cytoplasmic polyadenylation in Xenopus oocytes Polyadenylation is required before the mRNA can be translated, and regulation of this ... therefore necessary for oocyte maturation and embryonic development Cytoplasmic polyadenylation depends on phosphorylation of CPEB, a protein that is bound to specific cytoplasmic poly...

Ngày tải lên: 14/08/2014, 14:21

... regulation of duplucate genes by microRNA Dynamic simulation of regulation of duplucate genes by microRNA (a) A schematic diagram of a hypothetical microRNA-mediated regulatory circuit involving duplicate ... determine whether the observed enrichment of duplicated genes for microRNA regulation was in fact an intrinsic property of paralogs, or rather if it was a...

Ngày tải lên: 14/08/2014, 20:22

... transcripts zinc finger protein 42 zinc finger protein 143 zinc finger protein of the cerebellum XI Introduction CHAPTER I INTRODUCTION Introduction CHAPTER I INTRODUCTION Stem cells can be identified ... MEF feeders in the presence of serum The conditioned medium can support the normal growth of ES cells in the absence of feeders indicating that fibroblasts are pr...

Ngày tải lên: 14/09/2015, 14:07

... sources, named embryonic stem cells Literature review (ESCs), embryonic germ cells, fetal stem cells, umbilical cord stem cells, adult stem cells and induced pluripotent stem (iPS) cells (Ariff ... cell source for future clinical applications Literature review Table Characterization of stem cells by derivation source Category Embryonic stem cells Embryoni...

Ngày tải lên: 11/09/2015, 10:00

... (forward, 5¢-AAG GCT TAC CAC GAG CAG CTA TCA-3¢; reverse, 5¢-ACA GGC CAT GTA CTT TCC GTG TCT-3¢) and tobacco (forward, 5¢-ATG AGA GAG TGC ATA TCG AT-3¢; reverse, 5¢-TTC ACT GAA GGT GTT GAA-3¢) a- tubulinspecific ... VGCfEVY switch in regulating the expression of a zinc finger protein transcription factor isolated from Arabidopsis thaliana (AtZFP11) in both Arabidopsis and tobac...

Ngày tải lên: 16/03/2014, 06:20

... family, the miR-200 family have been reported in human [16,17] and mouse embryonic stem cells [18-20] The unique patterns of miRNA expression in embryonic stem cells suggest they are involved in maintaining ... instance, miR-373 induces the expression of E-cadherin and CSDC2 by targeting their promoter region and initiate their expression[ 73] Another me...

Ngày tải lên: 18/06/2014, 15:20

... ces 003 rof C 27 ta noisnetxe lanif dna ces 09 rof C 27 pmet noisnetxe ,ces 54 rof C 06 pmet gnilaenna ,ces 54 rof C 49 ta noitarutaned ,ces 06 rof C 49 ta noitarutaned laitini ,sgniwollof eht ... stibihni dica ciadiakO ]9[ )Mµ 001( niloksrofyxoedid ,1 dna )Mµ 001( niloksrof ,)Mµ 004( BP htiw srh 61 rof sllec amotapeh nekcihc gnitaert retfa dnuof osla saw 73A3PYC fo slevel tpircsnart fo ... s...

Ngày tải lên: 07/08/2014, 18:21

... differentially regulated by the two treatment conditions: rhOP-1 down-regulated LIF expression by more than 15-fold, IL-11 expression by more than eight-fold, IL-8 gene by four-fold and IL-6 by two-fold, ... Pathway analysis and classification by gene ontology Regulated genes (R > 1.5-fold, P < 0.001) were used as input for both analyses The ingenuity pathway analysis syst...

Ngày tải lên: 12/08/2014, 15:22