Anti cancer effects of aloe emodin cellular and proteomics studies

... effect 1.1.3.3 Anti- fungal, anti- protozaol and anti- bacterial effects 1.1.3.4 Other pharmacological effects 1.1.4 Anti- cancer potential of AE 1.1.4.1 Anti- mutagenic and anti- carcinogenic effects 1.1.4.2 ... GENERAL DISCUSSION AND CONCLUSIONS 5.1 Anticancer potential of AE: implication of proteomic findings 143 5.2 Anticancer potential of AE: induction of ap...

Ngày tải lên: 12/09/2015, 08:18

... damaging and telomeretelomerase effects and hence the mechanism of action of TQ in breast cancer cells In addition, it is of interest to investigate the effects of TQ in normal breast epithelial cells ... Black cumin seeds (left) and chemical structure of thymoquinone (right) 23 Figure 10 Growth inhibitory effects of TQ on breast cancer cells 39...

Ngày tải lên: 30/09/2015, 13:41

... Features of obesity- induced inflammation include increased production of proinflammatory cytokines, including TNF-a and IL-6 by white adipose tissue (WAT), and the activation of a network of pro-inflammatory ... remains in terms of understanding the antiinflammatory effects of nicotine in obesity- related inflammation and ulcerative colitis However, it is now kn...

Ngày tải lên: 18/06/2014, 22:20

... Features of obesity- induced inflammation include increased production of proinflammatory cytokines, including TNF-a and IL-6 by white adipose tissue (WAT), and the activation of a network of pro-inflammatory ... remains in terms of understanding the antiinflammatory effects of nicotine in obesity- related inflammation and ulcerative colitis However, it is now kn...

Ngày tải lên: 20/06/2014, 04:20

... HC, Wang YH, Liou KT, Chen CM, Chen CH, Wang WY, Chang S, Hou YC, Chen KT, Chen CF, Shen YC: Anti-inflammatory effects and mechanisms of the ethanol extract of Evodia rutaecarpa and its bioactive ... mechanisms for anti-inflammatory effects of Evodia rutaecarpa extracts and its bioactive components such as dehydroevodiamine (DeHE), evodiamine (Evo) and ru...

Ngày tải lên: 13/08/2014, 14:20

... matrine, supporting the further development of this novel delivery system for cancer therapy Materials and Methods Preparation of RGD-modified long circulating liposome (LCL) loading matrine (RGD-M-LCL) ... when the liposomes were reconstitutes in solvent Because matrine is a strongly hydrophilic and weakly alkaline drug, the encapsulation efficiency of liposomes for...

Ngày tải lên: 26/10/2012, 08:57

... present work, the effects of TQ on proteasome functionality were investigated both in isolated and in cellular complexes For this purpose, constitutive and immune -isolated proteasomes and two human ... likely to be the target of a nucleophilic attack [29] TQ effects on isolated 20S proteasomes To test TQ effects on isolated 20S constitutive and immunoprot...

Ngày tải lên: 15/03/2014, 11:20

... Broad band observed for carboxylic group disappeared in the spectra of complexes indicating deprotonation of ligand In the spectra of compounds V-VIII, appearance of new band of medium intensity ... mM of HEPES, and 0.22 μg of penicillin and streptomycin, respectively at 24°C in an incubator mg of each test compound (I-VIII) was dissolved in mL of water, ethano...

Ngày tải lên: 21/06/2014, 02:20

... before and after temsirolimus showed the direct cytostatic effect of this mTOR inhibitor through cell cycle arrest, as demonstrated by down-regulation of cyclin D1 and Ki67 in lymphoma cells, and ... http://www.jhoonline.org/content/3/1/30 areas, the count including a minimum of 1000 cells Fibrotic areas were randomized photographed at ×200 magnification for five fields and...

Ngày tải lên: 10/08/2014, 22:21

... PAF-AH assay analysis From the pellet of the 1st centrifugation (leukocytes and erythrocytes) the isolation of the leukocytes from the contaminating erythrocytes was achieved by erythrocyte sedimentation ... Figure In vitro inhibitory effect of antibiotics towards PAFCPT enzyme activity of rabbit leukocytes The amounts of each drug that induced approximately fifty to one hun...

Ngày tải lên: 11/08/2014, 03:20

... PAF-AH assay analysis From the pellet of the 1st centrifugation (leukocytes and erythrocytes) the isolation of the leukocytes from the contaminating erythrocytes was achieved by erythrocyte sedimentation ... Figure In vitro inhibitory effect of antibiotics towards PAFCPT enzyme activity of rabbit leukocytes The amounts of each drug that induced approximately fifty to one hun...

Ngày tải lên: 11/08/2014, 06:23

... research suggests another possible mode of action of yucca in preventing arthritis by anti-inflammatory activity Yucca contains anti-inflammatory polyphenolics such as resveratrol and yuccaols A, ... basis of the anti-protozoal activity of yucca saponins The chemistry and bioactivity of yucca saponins and phenolics have recently been reviewed by Piacente et al [21...

Ngày tải lên: 11/08/2014, 08:21

... published on the activity of the other diterpenes isolated from specimens collected at Providencia and San Andrés Islands We evaluated for the first time the anti-inflammatory activity of pseudopterosins, ... and the related IMNGD (Figure 1) isolated from the two chemotypes of P elisabethae collected at the Providencia and San Andrés Islands...

Ngày tải lên: 11/08/2014, 08:22

... as: Brodsky et al.: The anti-inflammatory effects of the tellurium redox modulating compound, AS101, are associated with regulation of NFB signaling pathway and nitric oxide induction in macrophages ... kinetics I At h, AS101 probably enters the nucleus and may interfere with the DNA-binding ability of the NFB complex resulting in...

Ngày tải lên: 11/08/2014, 08:22