comparing the anti apoptotic effects of phl and leo

... 3.3.1.3 Comparison of the effects of pHL and Leo on the activities of SOD, CAT, GPx and GST in the cortex following TBI 78 3.3.2 Comparing the anti- apoptotic effects of pHL and Leo 79 3.3.2.1 ... 3.3.1 Comparing the antioxidant effects of pHL and Leo 75 3.3.1.1 DPPH radical-scavenging activities of pHL, Leo and VC (positive control) 75 3.3.1.2 EC50 values of VC, pHL and Leo ... cleaved PARP in the brain tissue to identify the effects of pHL on anti- apoptotic mechanisms 1.2 Studies to address the effects of Leo on antioxidant activity and the expression of apoptotic pathway...

Ngày tải lên: 02/10/2015, 17:15

... together with the degree of overhang of the prosthesis in millimeters and the presence or absence of posterior osteophyte Each prosthesis was then scored radiographically by summing the degree of ... preparation and analysis of the results of this study I would like to acknowledge the help of Matthew Hankins of the Brighton and Sussex University Department of Statistics, for his advice and statistical ... between the varus/valgus positioning of the femoral component and the Oxford score (0.38) Examples of good and poorly positioned prosthesis can be seen in Figures and Edmondson et al Journal of Orthopaedic...

Ngày tải lên: 20/06/2014, 07:20

... coli cells In the structure the base of bound GMP is stacked between Val143 and Phe194 N1, N2 and O6 of the nucleotide form hydrogen bonds to main chain atoms, whereas the side chain of Lys173 interacts ... Lys173 interacts with both O6 and N7 (Fig 1C) The 2¢OH of the ribose is hydrogen bonded to the main chain and the side chain of Asp142 (Fig 1C) Both hydroxyl groups of the ribose are involved in ... Asp142, 2¢ and 3¢OH of the ribose and three water molecules with ˚ coordination distances of approximately 2.4 A The phosphate of the GMP is hydrogen bonded to main chain and side chain atoms of amino...

Ngày tải lên: 15/02/2014, 01:20

... of cysteines The involvement of four conserved cysteines in the coordination of the [4Fe–4S] cluster has been confirmed in WhiB3 [9] and WhiB4 [15] The brown color of the purified protein and the ... conditions [15] The rate of disintegration was directly correlated with the duration and strength of the oxidizing environment Similarly, in this study, the intensity of the brown color and the iron–sulfur ... except WhiB2, the amino acid immediately after the C-terminal cysteine of the CXXC motif is proline (Fig S6) In WhiB2 the absence of proline and therefore of the kink might not allow the protein...

Ngày tải lên: 18/02/2014, 12:20

... structure of the C2-SurE to a resolution of ˚ 2.7 A In both crystal forms the electron density accounted for the majority of the residues There were no disordered regions in the map The quality of refinement ... features of the protein St SurE is an aba sandwich protein and adopts the Rossmann fold as in archaic and thermophilic homologues The St SurE monomer consists of 13 b-strands, six a-helices and three ... is the jth observation of reflection h and is its mean intensity a on the other side (Fig 1A,B) One noticeable difference between St SurE and the other SurEs is the short length of g1 and...

Ngày tải lên: 18/02/2014, 14:20

... of new therapies and ⁄ or vaccines, or the improvement of existing ones, necessary to control this disease The identification and characterization of the proteins involved in the interaction of ... (HABP) involved in the binding to and invasion of monocytes (U937) and type II alveolar epithelial cells (A549), using synthetic peptides The protein encoded by the Rv2560 gene was synthesized in 20-mer-long, ... did not predict the existence of a signal peptide, the high grand average of hydropathicity (GRAVY) value (0.488) and the existence of four possible transmembrane helices in the complete Rv2560...

Ngày tải lên: 18/02/2014, 16:20

... established Of two possible dimeric structures of LPL, the head-tohead and the head-to-tail models, the studies of the chimeric proteins of hepatic lipase and LPL and the tandem repeat approach of LPL ... the C-terminal domain of apoCII interacts with the interface of the N- and C-terminal domains of LPL and part of the lid surface [32] Because the functional importance of LPL’s C-terminal domain ... illustrates the overall saddle shape of the dimeric structure and the key heparin-binding residues in the N-terminal domain held coordinately by the two subunits on the top of the hollow (Fig 1A) The...

Ngày tải lên: 21/02/2014, 15:20

... (Table 1) They display, however, greater heterogeneity in the molecular mass of the detected protein band, as is also the case for metal cation dependence, as the sPPase activity of many of these ... regulated by the same factors Analysis of the promoter regions of 3954 Sequence and phylogenetic analysis Knowledge of the N-terminal sequences of the three cyanobacterial sPPases purified and characterized ... salt (MgCl2) and mm Na4PPi (standard assay conditions) The reaction was started by the addition of enzyme, and the PPi released after 10 was determined When the efficiencies of other divalent...

Ngày tải lên: 16/03/2014, 11:20

... follicles were cut open and the theca and adherent granulosa cells peeled from the stroma The granulosa cells were then gently scraped from the theca and the granulosa and theca cells were snap ... [21,22] The objectives of the studies reported here were to examine the interactions of the gonadotrophins and IGF with the Akt and Erk signalling pathways in theca and granulosa cells in vitro and ... Analysis of variance using the GLM procedures of SAS was used to determine the effects of treatment on the levels of Akt, p-Akt, Erk and p-Erk in granulosa and theca cells All values are given as the...

Ngày tải lên: 20/06/2014, 07:20

... with head and trunk turned to the opposite side The supraclavicular part of the plexus was exposed through a transverse incision cm above the clavicle at the root of the neck and the C5 and C6 roots ... patients and the final grading of their elbow and shoulder function are detailed in Table Table details the motor grade of the recovered muscles and the final range of movement achieved Table shows the ... of the location in the ulnar nerve The chosen fascicle is separated from the rest of the nerve It must be divided cm distal to the level of the possible coaptation to turn laterally to meet the...

Ngày tải lên: 10/08/2014, 10:20

... both myopathy and neuropathy [4] The combination of neurophysiological testing with neuromuscular histology could therefore help in the precise identification of the type and severity of neuromuscular ... both syndromes Because of this, and because of the lack of studies evaluating neuromuscular disorders in ICUs using a combination of histopathological (nerve and muscle) and electromyographic ... tetraparesis and failure to wean Peripheral electromyographic analysis and neuromuscular biopsy were performed in all of these patients to determine the cause of limb weakness and diaphragm dysfunction The...

Ngày tải lên: 12/08/2014, 20:20

... very poor Furthermore, patients and relatives, regardless of the functional outcome, were asked whether they were satisfied with their treatment on our neurocritical care unit Materials and methods ... probability of early death) The possibility of answering the question of retrospective consent to neurocritical care was dichotomized Finally, (d) patients were asked whether they were satisfied with their ... http://ccforum.com/content/14/4/R144 Page of tests were two-sided, and the significance level was set at a = 0.01 The distribution of the data was assessed with the Kolmogorov-Smirnov test Continuous and categoric variables...

Ngày tải lên: 13/08/2014, 21:21

Ngày tải lên: 14/11/2014, 08:21

... development, vision and other sensations The cerebral cortex, which makes up the superficial aspect of the cerebrum, is the most complex and important structure of the human brain The surface of the human ... as the largest and most prominent part of the human brain, is the control center of it It is 85% of the weight of a human brain Structurally, it is divided into two hemispheres, the left and the ... coefficient measures the extent of inter-connectivity among the neighbors of the node It is defined as the ratio of the number of existing connections among the node i’s neighbors and all their possible...

Ngày tải lên: 09/09/2015, 18:53

... ascertain the exact position of each atom in the asymmetric unit of the crystal Calculation of electron density is dependent on two main factors; the amplitude and the phase of the diffracted beam These ... products during each cycle of the PCR reaction It is one of the technologies of the genomic age and has become the method of choice for detection of gene expression at the mRNA level Several factors ... Wu Jinlu, Ms Tang Xuhua, Ms Sunita and, Mr Jobi and the rest of the lab mates for the valuable discussion and friendship and the present and former members of Functional Genomics Laboratory as...

Ngày tải lên: 14/09/2015, 09:57

... to the family Enterobacteriaceae Most of the E coli strains are harmless and are found in the intestines of mammals The harmless strains are part of the normal flora of the gut, and can help their ... for EPEC, except for the presence of the Stxencoding phage on the EHEC chromosome and the presence of the characteristic EHEC 60-Mda plasmid instead of the EAF plasmid of EPEC The EHEC plasmid is ... (e.g., the immunoglobulin G proteases and the VacA toxin) Examples of T5SS encoded by PAI are LPA and the EspC PAI of the pathogenic E coli, SPI-3 of S enterica, and SHI-1 of S flexneri (Schmidt and...

Ngày tải lên: 14/09/2015, 14:13

... assess the global burden of disease It is calculated as the sum of years of life lost and years of life lived with disability The overall incidence rate of stroke is around 2-2.25 per thousand population ... to the stroke patients Study Period: Clinical data set was collected at the point of admission of the patients to the two community hospitals and upon their discharges from the hospitals The ... of the medical complication/s (2) Date of medical complication/s The information on the following variables was recorded at the point of discharge (planned -discharges) of the patients from the...

Ngày tải lên: 04/10/2015, 10:24

... interspersed by a stimulus which deviated from the standard in the intensity of the first component and the glide direction of the second constituent The number of distinct MMN components elicited by ... et al The relationship of age, gender, handedness, and sidedness to the size of the corpus callosum Academic Radiology 1994; 1:243-248 69 Driesen NR, Raz N The influence of sex, age, and handedness ... P300 and the N2b Data indicate that the P300 is involved not only in processes of working memory, but may interact with the N2b in the control of motor response to external cues Through the use of...

Ngày tải lên: 02/11/2012, 11:08

... included: semi tandem stand, full tandem stand, rising from chair without using arms and shoulder external rotation (full) A younger member of the household present at the time of the interview ... assessment of the informant of the health status of the elderly person was obtained Results The non-response rate for the study was only 1.7% In response to the question "Are you healthy ?", 49% of males ... in the urban areas and from the Grama Niladhari divisions (smallest administrative units) in the rural areas Using the electoral register for each of the clusters, 20 persons of age 60 years and...

Ngày tải lên: 14/02/2014, 06:20

... independently of the presence of AREs (Fig 6B, lanes and 5) It is possible that in the region located before the AREs, consisting of 343 bp of the 3¢ UTR of the IL-1b transcript, there is a putative ... contained 343 bp of the 3¢ UTR region (nucleotides 898–1227 of the 3¢ UTR region) The construct encoding IL-1b cDNA with AREs (IL1+ARE) contained 423 bp of the 3¢ UTR (nucleotides 898–1318 of the 3¢ UTR ... mRNA and also of its own transcript For this reason, the level of mRNA for the wildtype form of MCPIP and the level of mRNA for IL-1b (Fig 5A, lane 3) were lower in comparison to the level of mRNA...

Ngày tải lên: 18/02/2014, 14:20