The plasma membrane lipid rafts caveolae mediated PACAP signalling in PC12 cells

... definition of lipid rafts 17 1.2.2 The definition of caveolae 18 1.2.3 The composition of lipid rafts/ caveolae 20 1.2.3.1 Proteins in lipid rafts/ caveolae 20 iii 1.2.3.2 Lipids in lipid rafts/ caveolae ... cAMP in lipid rafts/ caveolae- mediated PACAP signaling in PC12 cells 4.2.5 ERK kinase1/2 (MEK1/2) is regulated by PACAP in PC12 cells...

Ngày tải lên: 12/09/2015, 08:16

... al.: Trichoderma viride cellulase induces resistance to the antibiotic pore-forming peptide alamethicin associated with changes in the plasma membrane lipid composition of tobacco BY-2 cells BMC ... from ATP synthesis We then investigated whether the alamethicin resistance of the tobacco cell cultures involved de novo protein synthesis...

Ngày tải lên: 11/08/2014, 11:21

... in the HD -caveolae and LD -caveolae; (c) the VHD -caveolae contained almost a third of the plasma membrane caveolin, and the majority of cellular caveolin is found in the plasma membrane of adipocytes; ... referring to all of them as caveolae, was demonstrated by their content of both caveolin-1 and caveolin-2 The coexistence of caveolin-1 and...

Ngày tải lên: 16/03/2014, 13:20

... al Dissociation of tubulin H+-ATPase complex by glucose H+-ATPase activity of isolated plasma membrane is inhibited by tubulin Plasma membranes isolated from S cerevisiae were incubated in the ... hydrophobic tubulin partitioning into the detergent phase (HAT) is the acetylated tubulin forming a complex with H+-ATPase The finding of the H+-A...

Ngày tải lên: 23/03/2014, 11:20

... the anesthetics benzyl alcohol, propofol, chloroform and diethyl ether reversed the resistance by acceleration of the passive transport of the drug or dye across the plasma membrane At these concentrations, ... concentrations, the anesthetics further enhanced the rate of passive drug permeation and interfered with the active export of the drug...

Ngày tải lên: 30/03/2014, 04:20

... (2002) A novel interaction partner for the C-terminus of Arabidopsis thaliana plasma membrane H+-ATPase (AHA1 isoform): site and mechanism of action on H+-ATPase activity differ from those of 14-3-3 ... Rasi-Caldogno F (1998) Fusicoccin binding to its plasma membrane receptor and the activation of the plasma membrane H+-ATPase IV Fusicoccin induce...

Ngày tải lên: 19/02/2014, 07:20

... [13] The levels of expression of various proteins (Adxp, Adrp, CYP11A1) involved in the reaction can also affect the efficiency of cholesterol side chain cleavage Indeed, it is apparent that the expression ... ATF2 gene Therefore, both free pregnenolone production and the efficient coupling of the SCC and the 3b-HSD activities in yeast require the use of...

Ngày tải lên: 08/03/2014, 08:20

... shown) Together, these results indicate that R24, once internalized, is recycled to the plasma membrane and released into the culture medium R24 antibody recycling is sensitive to BFA and dependent ... Taken together, our results indicate that the GD3 R24 complex is rapidly endocytosed in CHO-K1 and SK-Mel 28 melanoma cells, accumulates in the recycli...

Ngày tải lên: 16/03/2014, 13:20

... quenching occurs as a result of dye moving within the outer leaflet of the plasma membrane The lipid core of the plasma membrane constitutes the main barrier to TMRM transport across the membrane and ... leaflet of the plasma membrane suggest that uptake of TMRM occurs in distinct steps: rapid binding to the outer surface of the cells, flip-flop a...

Ngày tải lên: 29/03/2014, 08:20

... http://www.biomedcentral.com/1471-2229/6/22 At3 g62220 At3 g17410 Arabidopsis thaliana Arabidopsis At1 g48210 thaliana Arabidopsis At2 g47060 Arabidopsis thaliana thaliana gi|51038251 Oryza sativa At1 g48220 Arabidopsis thaliana M-[GS]-C-F-[AGS]-[CFW]-C ... Myr:GFP was cloned by in vitro annealing of oligonucleotides Myr -A (5'-P-gatccatgggatgcttttcatgctgctgtgtggcagatgacgacaacgttggcag...

Ngày tải lên: 12/08/2014, 05:20

... transduction pathway( s) triggered by prosaposin may be responsible for SphK activation Taken together, these findings point to a role of lipid rafts in the prosaposin -triggered signalling pathway, thus ... signalling pathways involved in cell death prevention triggered by prosaposin occur through lipid rafts In addition, DNA fragmentation was quantified as...

Ngày tải lên: 24/03/2014, 00:21

... exposure of liver cells to FFAs Interruption of TAG synthesis in conditions of excess availability of SFAs is the key point in the molecular mechanism of SFA-induced lipotoxicity It is suggested ... constitutes the initiating event in the process of lipotoxicity Stearate has to be activated in order to be toxic The first enzyme involved in me...

Ngày tải lên: 14/02/2014, 22:20

... Fig ATP-binding domain of HSP70 is essential for the inhibition of H2O2-induced activation of caspases-9 and -3 and apoptosis (A) The effects of HSP70 and its deletion mutant proteins on the ... activation Such a mechanism is independent of the interaction of HSP70 with Smac but requires the ATP-binding domain of the protein However,...

Ngày tải lên: 16/03/2014, 01:20

... steroid synthesis, the release of AA into the mitochondria is the first stimulator of cholesterol transport The sustained phase of the acute response will then need the induction of StAR We cannot ... mitochondria The absence of hormone ⁄ cAMP- induced steroid synthesis when protein synthesis is inhibited can be explained now by the inhibition in the ind...

Ngày tải lên: 16/03/2014, 12:20

... activation of the Smad pathway independently of the TGF-b ligand Fig PC12 cells express low levels of endogenous TbRII (A) C-terminal phosphorylation of Smad2 was investigated in either parental PC12 cells ... Smad activation occurs independently from phosphorylation at the C-terminal SSXS-motif Involvement of Smad4 in NGF-triggered activation of t...

Ngày tải lên: 16/03/2014, 16:20