... 12(4):314-325 114 Higashimoto Y, Yamagata Y, Taya S, Iwata T, Okada M, Ishiguchi T, Sato H, Itoh H: Systemic inflammation in chronic obstructive pulmonary disease and asthma: Similarities and differences ... molecular fingerprint is analysed, would increase the accuracy of disease diagnosis, aid earlier disease detection, allow for improved clarification of disease subtypes and allow automation for ... methods for diagnosing COPD rely on spirometry combined with the use of questionnaires and other arbitrary measures for disease classification Adopting a systems biology approach, whereby a disease...