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A functional genomics approach for elucidation of novel mechanisms involved in GnRH regulation of the gonadotropins

A functional genomics approach for elucidation of novel mechanisms involved in GnRH regulation of the gonadotropins

A functional genomics approach for elucidation of novel mechanisms involved in GnRH regulation of the gonadotropins

... A FUNCTIONAL GENOMICS APPROACH FOR ELUCIDATION OF NOVEL MECHANISMS INVOLVED IN GnRH REGULATION OF THE GONADOTROPINS By LUO MIN (B SC.) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY ... regulate the synthesis of the gonadotropins directly at the pituitary or indirectly at the hypothalamus by modulating GnRH secretion The gonadal peptides: inhibin, activin and follistatin (FS) also ... pathways activated by GnRH GnRH activates a number of signaling pathways, including MEK, JNK, ERK1/2, cAMP/PKA, PKC, Ca2+ and CaM-dependent pathways A number of transcription factors are activated...
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USING THE ANALYTIC HIERARCHY PROCESS APPROACH FOR ASSESSMENT OF THE STRENGTH OF UNIVERSITY-INDUSTRY-GRI COOPERATION IN VIETNAM

USING THE ANALYTIC HIERARCHY PROCESS APPROACH FOR ASSESSMENT OF THE STRENGTH OF UNIVERSITY-INDUSTRY-GRI COOPERATION IN VIETNAM

... identify the strength of the individual linkage by determining the relative importance of the linkage types The goal is at the top of the model 4.4.2 The Actors Like the AHP model formulated for overall ... involvement in the process of technological assessment The objective of this study is to apply the Analytic Hierarchy Process (AHP) for assessing the strength of University-Industry-GRI cooperation ... At the bottom of the model, the alternatives of individual linkage hierarchy are the existing linkage types This level will determine the rank of linkage type The hierarchy developed for individual...
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Tài liệu Báo cáo khoa học: Application of a fluorescent cobalamin analogue for analysis of the binding kinetics A study employing recombinant human transcobalamin and intrinsic factor pdf

Tài liệu Báo cáo khoa học: Application of a fluorescent cobalamin analogue for analysis of the binding kinetics A study employing recombinant human transcobalamin and intrinsic factor pdf

... Expression and purication of human recombinant IF and TC The recombinant Cbl binding proteins and their fragments were isolated from plants and yeast as described earlier [9,17] Preparation of the unsaturated ... Fedosova NU, Nexo E & Petersen TE (2002) Comparative analysis of cobalamin binding kinetics and ligand protection for intrinsic factor, transcobalamin, and haptocorrin J Biol Chem 277, 99899996 Cannon ... uorophore, as was expected from the crystallographic data for TCCbl complex [16], and the binding- dissociation curves of CBC and Cbl were identical (Figs 2B,4B Application of a uorescent Cbl analogue and...
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Báo cáo khoa học: TioS T-TE – a prototypical thioesterase responsible for cyclodimerization of the quinoline- and quinoxaline-type class of chromodepsipeptides potx

Báo cáo khoa học: TioS T-TE – a prototypical thioesterase responsible for cyclodimerization of the quinoline- and quinoxaline-type class of chromodepsipeptides potx

... for the iterative assembly of the quinoline- and quinoxaline-type class of chromodepsipeptides, capable of macrolactonization and macrothiolactonization The substrate specificity of TioS T-TE was ... iterative ligation and macrocyclization platform that is capable of catalyzing macrolactonization and a so far unreported macrothiolactonization Initially, TioS T-TE was tested using a linear ... establish TioS T-TE as a general catalyst for the ligation and cyclization of the quinoline- and quinoxaline-type class of chromodepsipeptides, TL11 was synthesized The primary sequence was based on...
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Báo cáo y học:

Báo cáo y học: "A need for a ‘whole-istic functional genomics’ approach in complex human diseases: arthritis" pptx

... using a singular rather than a plural noun, implying that it might be a single process or a type of process The avascular, alymphatic and aneural human OA-affected articular cartilage harboring ... retrieved complex data in a way that aids their interpretation Integrating various incompatible bioinformatics platforms is essential Such efforts are currently under way by the Interoperable Informatics ... give a comprehensive analysis of a complex disease, but rather would require an entire arsenal of approaches as recently described by Amin and coworkers [5,6] A strategy for genomic analysis in arthritis...
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Báo cáo y học:

Báo cáo y học: " Systems biology coupled with label-free high-throughput detection as a novel approach for diagnosis of chronic obstructive pulmonary disease" pptx

... 12(4):314-325 114 Higashimoto Y, Yamagata Y, Taya S, Iwata T, Okada M, Ishiguchi T, Sato H, Itoh H: Systemic inflammation in chronic obstructive pulmonary disease and asthma: Similarities and differences ... molecular fingerprint is analysed, would increase the accuracy of disease diagnosis, aid earlier disease detection, allow for improved clarification of disease subtypes and allow automation for ... methods for diagnosing COPD rely on spirometry combined with the use of questionnaires and other arbitrary measures for disease classification Adopting a systems biology approach, whereby a disease...
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Báo cáo y học:

Báo cáo y học: " A novel approach for prediction of tacrolimus blood concentration in liver transplantation patients in the intensive care unit through support vector regression" doc

... used instead of 15 and 16 variables by the linear methods Apparently, these input variables contained more information in a nonlinear way than the other 15 or 16 contained in a linear way When a ... relevant input variables Background Hospital information systems in intensive care medicine generate large datasets on a daily basis These rapidly increasing amounts of data make the task of extracting ... doses of tacrolimus, namely the dose at a. m and p.m from the three days (day 1, day 2, and day 3) before the day of the measured tacrolimus blood concentration (day 0) Coadministered medications...
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Tài liệu Báo cáo khoa học: A systems biology approach for the analysis of carbohydrate dynamics during acclimation to low temperature in Arabidopsis thaliana doc

Tài liệu Báo cáo khoa học: A systems biology approach for the analysis of carbohydrate dynamics during acclimation to low temperature in Arabidopsis thaliana doc

... identification and simulation A mathematical model was developed, representing central carbohydrate metabolism in leaves of A thaliana The model was based on the following system of ordinary differential ... in A thaliana A D B E C F Fig Maximum activities of enzymes in central carbohydrate metabolism during cold exposure (A C) Vmax values of three invertase isoforms: vInv, nInv and eInv (D) Vmax of ... (1999) Acclimation of Arabid¨ opsis leaves developing at low temperatures Increasing cytoplasmic volume accompanies increased activities of enzymes in the Calvin cycle and in the sucrose-biosynthesis...
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Báo cáo khoa học:

Báo cáo khoa học: "A GENERATIVE GRAMMAR APPROACH FOR THE MORPHOLOGIC AND MORPHOSYNTACTIC ANALYSIS OF ITALIAN" ppt

... Emilia I the first is the suffix itself the second is the stem of the suffix (the access key to the table) the third is the ending class of the suffix the fourth is the syntactic class of the suffix ... syntax They are recognized by means of a context-free grammar, the first is the stem of the alteration (the access key in the tablc l the second is the ending class of the alteration the third is the ... performed: I the analysis can be performed completely the lemma can neither be altered nor affixed (this is the case for example of prepositions and conjunctions) only the longest analysis of the...
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Báo cáo hóa học:

Báo cáo hóa học: " Research Article A Generalized Halanay Inequality for Stability of Nonlinear Neutral Functional Differential " ppt

... Inequalities and Applications L P Wen, Y X Yu, and W S Wang, Generalized Halanay inequalities for dissipativity of Volterra functional differential equations,” Journal of Mathematical Analysis and ... paper, we consider a more general inequality and use this inequality to discuss the stability of nonlinear neutral functional differential equations NFDEs and a class of nonlinear neutral delay ... of almost periodic solutions for quasilinear delay systems and the Halanay inequality, ” Journal of Mathematical Analysis and Applications, vol 248, no 2, pp 625–644, 2000 H Tian, “Numerical and...
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Báo cáo hóa học:

Báo cáo hóa học: "Research Article A Rules-Based Approach for Configuring Chains of Classifiers in Real-Time Stream Mining Systems Brian Foo and Mihaela van der Schaar" pot

... proposed a rules-based framework for reconfiguring distributed classifiers for a delay-sensitive stream mining application with dynamic stream characteristics By gathering information locally at each ... binary classifier partitions input data objects into two classes, a “yes” class H and a “no” class H A binary classifier chain is a special case of a binary classifier tree, where multiple binary classifiers ... different stream characteristics, the proper algorithm to use, for classifier reconfiguration We focus on a chain of binary classifiers as our main application [4], since chains of classifiers are easier...
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Báo cáo hóa học:

Báo cáo hóa học: " Research Article A Two-Stage Approach for Improving the Convergence of Least-Mean-Square Adaptive Decision-Feedback Equalizers in the Presence of Severe " doc

... This validates the analysis performed in Section 5.3 It is also seen that the performance of the systems improves as the number of filter taps is increased, approaching the performance of QPSK The ... with the adaptive algorithm The first stage is the training phase, where known training symbols are used to push the filter in the direction of the optimal weights After the training symbols have ... reference for the interferer during adaptation and is thus forced to converge on the basis of the training data only The feedback taps converge slower than the feedforward taps because the DFE...
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A FUNCTIONAL-ANALYTIC METHOD FOR THE STUDY OF DIFFERENCE EQUATIONS EUGENIA N. PETROPOULOU AND potx

A FUNCTIONAL-ANALYTIC METHOD FOR THE STUDY OF DIFFERENCE EQUATIONS EUGENIA N. PETROPOULOU AND potx

... to study partial difference equations of three and four variables The aim of this paper is to present the generalization of this functional-analytic method for the study of linear and nonlinear ... to apply Theorem 1.1 to the preceding operator equation and obtain information for the initial linear difference equation under consideration In the case of nonlinear equations, we some manipulation ... generating analytic functions, Laurent or z-transforms, numerical schemes, boundary value problems of partial differential equations, problems of quantum mechanics, and problems of population dynamics...
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Báo cáo hóa học:

Báo cáo hóa học: " A New Approach for Estimation of Instantaneous Mean Frequency of a Time-Varying Signal" doc

... USA, May–June 1999 Estimation of Instantaneous Mean Frequency [10] H K Kwok and D L Jones, “Improved instantaneous frequency estimation using an adaptive short-time Fourier transform,” IEEE Trans ... of adaptive TFDs is based on signal decomposition In practice, no TFD may satisfy all the requirements needed for instantaneous feature extraction and identification for nonstationary signal analysis ... suitable for estimating the IF of a signal ADAPTIVE TIME -FREQUENCY DISTRIBUTIONS The purpose of this paper is to explore the best available TFD for estimating the IF of a signal For simple applications...
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Báo cáo lâm nghiệp:

Báo cáo lâm nghiệp: "Assessment of the assortment potential of the growing stock – a photogrammetry based approach for an automatized grading of sample trees" potx

... administration and supply of the assortment criteria for the grading routine, a database application thar-QDB (Tharandt Quality Data Base) was developed as subject-matter of a diploma thesis [19] The ... (iv) a marketoriented evaluation approach for the growing stock The article reports primarily the results of the photogrammetrical investigation and the automatized grading A total of eight Norway ... eCognition software An application example of the differences between “normal” and “improved” grading will be presented for two sample trees The data base application and the evaluation approach will...
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