Proline rich acidic protein 1 in life and death 2
Proline rich acidic protein 1 in life and death 2
... 71 2 .10 .2 .1 Labeling of protein with Alexa Fluor dye 71 2 .10 .2. 2 Bacteria binding assay using labeled protein 71 2 .11 DNA damage assay 72 2 .11 .1 Alkaline single-cell ... 14 1 3 .11 .2 PRAP1 interacts with Hsp 70 14 1 3 . 12 Role of PRAP1 in apoptotic cells 14 5 3 . 12 .1 Induction of PRAP1 expression in apoptotic cells 14 5 3 . 12 .2 PRAP1 binds to ... 40...
Ngày tải lên: 11/09/2015, 16:05
Proline rich acidic protein 1 in life and death 3
... 76 3 .1 PRAP1 and intestinal differentiation 3 .1. 1 PRAP1 is expressed in epithelial cells of the intestines The expression of PRAP1 in human intestinal tract was studied using immunohistochemistry ... 77 Figure 3 .11 PRAP1 is expressed in the epithelial cells of small intestine Representative figure showing PRAP1 immunohistochemical staining in normal human small intestine...
Ngày tải lên: 11/09/2015, 16:05
Proline rich acidic protein 1 in life and death 4
... (p53-/-) and one with p 21 knockout (p 21- /-) PRAP1 mRNA was induced in both HCT 11 6 wild-type and p 21- /- cell lines, but not in p53-/- 10 6 Figure 3.37 Early upregulation of PRAP1 in a dose- and time-dependent ... 5-FU induced an increase in cyclin E1 and cyclin A1 protein levels, reflecting an arrest at S-phase (Figure 3.55) Repression of PRAP1 induction by 5FU caus...
Ngày tải lên: 11/09/2015, 16:05
Proline rich acidic protein 1 in life and death 5
... Identification of PRAP1 binding protein by MS-MS Representative figure showing the identification of PRAP1 binding proteins after performing MS-MS Figure 3. 71 PRAP1 physically interacts with Hsp ... F-actin in HCT 11 6 cells stably expressing PRAP1 (PRAP1) and its empty vector control stable cell line (Vector), or after transfection of control siRNA and PRAP1 siRNA for 72 hours F-a...
Ngày tải lên: 11/09/2015, 16:05
Proline rich acidic protein 1 in life and death r6
... DISCUSSION 17 3 4 .1 Role of PRAP1 in differentiated epithelial cells 4 .1. 1 Regulation of PRAP1 by differentiation 4 .1. 1 .1 Expression of PRAP1 in intestinal epithelium The proline- rich acidic protein (PRAP1) ... floating cells, we employed the annexin V-FITC staining assay Annexin V is a phospholipid binding protein that has a high binding affinity for phosphatidylserine...
Ngày tải lên: 11/09/2015, 16:05
Báo cáo khoa học: Retention of the duplicated cellular retinoic acid-binding protein 1 genes (crabp1a and crabp1b) in the zebrafish genome by subfunctionalization of tissue-specific expression doc
... detection of cellular retinoic acid binding proteins I and 3570 R.-Z Liu et al 15 16 17 18 19 20 21 22 23 24 25 26 27 28 II with new antibodies J Histochem Cytochem 46, 11 03 11 11 Zetterstrom RH, Lindqvist ... (19 90) Retinoic acid receptors and cellular retinoid binding proteins I A systematic study of their differential pattern of transcription during mouse organo...
Ngày tải lên: 16/03/2014, 22:20
Báo cáo khoa học: Synergistic co-operation of signal transducer and activator of transcription 5B with activator protein 1 in angiotensin II-induced angiotensinogen gene activation in vascular smooth muscle cells potx
... Janus kinase ⁄ signal transducer and activator of transcription signaling pathway mediate the regulation of systemic and tissue localized renin -angiotensin system Mol Endocrinol 18 , 10 33 10 41 11 Xu ... studies indicate that transcription activation by STATs requires activated AP -1 [11 13 ] AP -1 is a complex composed of the Fos and Jun proteins [14 16 ] In...
Ngày tải lên: 30/03/2014, 02:20
Báo cáo y học: " Tumour necrosis factor-α stimulates dehydroepiandrosterone metabolism in human fibroblast-like synoviocytes: a role for nuclear factor-κB and activator protein-1 in the regulation of expression of cytochrome p450 enzyme 7b" doc
... Colosia AD, Donahue JP, Lin YZ, Hawiger J: Regulation of NF-kappa B, AP-1, NFAT, and STAT1 nuclear import in T lymphocytes by noninvasive delivery of peptide carrying the nuclear localization ... stress-activated protein kinases, also called cJun NH2-terminal kinases (JNKs); and the p38 MAPKs [13] The JNK pathway is of interest because of its capacity to phosphorylat...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "Osteogenic protein 1 in synovial fluid from patients with rheumatoid arthritis or osteoarthritis: relationship with disease and levels of hyaluronan and antigenic keratan sulfate" ppt
... Content of osteogenic protein protein in synovial fluid samples The samples osteogenic protein (OP -1) content of synovial fluid from asymptomatic donors (donor) and from osteoarthritis (OA) and rheumatoid ... therefore not surprising and may have a prognostic and /or diagnostic value for the inflammatory processes in articular joints a prior history of jo...
Ngày tải lên: 09/08/2014, 08:22
Role of poly (ADP ribose) polymerase 1 and copper homeostasis factor, antioxidant protein 1 in the maintenance of genomic integrity
... .14 1. 1.2.3 Radiation 18 1. 1.3 Mechanisms for preventing genomic instability 20 1. 1.3 .1 Poly (ADP- ribose) polymerase (PARP -1) 21 1 .1. 3 .1. 1 Role of PARP -1 at the telomeres 24 1. 1.4 ... 1. 1.4 Copper metabolism and disease 27 1. 1.4 .1 PARP -1 and Copper metabolism .29 1. 1.5 1. 2 1. 3 1. 4 Genomic Instability 1. 1 .1. 1 Telomere mediated...
Ngày tải lên: 11/09/2015, 10:18
Roles of TACC related protein, mia1p in MTOCs and microtubule dynamics in schizosaccharomyces pombe 1
... 3 .1 Mia1p in assembly and maintenance of persisent iMTOCs at nuclear envelope 44 3 .1. 1 Lack of microtubule binding protein Mia1p results in fewer interphase Microtubules 44 3 .1. 1 .1 Mia1p is a microtubule ... cytoskeleton 18 18 1. 2.4 .1. 1 Architecture and dynamics of interphase microtubule cytoskeleton 18 1. 2.4 .1. 2 Functions of interphase microt...
Ngày tải lên: 12/09/2015, 08:19
Báo cáo khoa học: Identification of the amniotic fluid insulin-like growth factor binding protein-1 phosphorylation sites and propensity to proteolysis of the isoforms docx
... degradation of IGFBP-1 isoforms The y-axis shows the percentage of the ratio between the spot area of the degraded and that of the untreated protein measured using IMAGE J 1.37V software the presence of ... almost to the same extent as the unmodified protein and that the susceptibility to proteolytic degradation of the isoforms increased with the...
Ngày tải lên: 07/03/2014, 00:20
Báo cáo khoa học: Modulation of glucocorticoid receptor-interacting protein 1 (GRIP1) transactivation and co-activation activities through its C-terminal repression and self-association domains pptx
... I 13 98 + 14 62 11 22 13 05 10 13 + 13 98 13 05 11 22 13 98 14 62 14 62 10 13 11 22 13 05 13 98 14 62 + 14 62 13 98 11 22 11 22 10 13 13 05 62 13 98 14 62 13 05 13 98 11 22 13 05 62 13 98 13 05 III 11 22 10 13 IV AD1 ? ? Repression ... FEBS 217 9 Autoregulation of GRIP1 functions via C-terminal region P.-Y Liu et al 11 22 13 05 10 13 13 98 14 62 11...
Ngày tải lên: 07/03/2014, 12:20