Integrative methods for discovering generic CIS regulatory motifs

... novo motif finders for discovering regulatory motifs In the literature, there are three existing approaches for performing ensembles for motif finding: Re-rank collection of motifs returned by ... computational methods offer a great hope This thesis presents a new class of algorithms for in silico discovery of regulatory elements Firstly, we address the problem of motif findin...

Ngày tải lên: 11/09/2015, 16:03

... confirmed individual bicoid binding sites in these sequences, these sequences not contain clusters of bicoid binding sites Assessment of gene regulation Enhancers may contain clusters of TF binding ... Individual regulatory segment of DNA can contain many binding sites for several factors, often substantially overlapping with each other [5] This brings about a problem of s...

Ngày tải lên: 12/08/2014, 17:20

... which were then functionally assayed by generating and analyzing three independent stable transgenic lines for the vast majority of the constructs In each case, the pattern of expression of the EGFP ... 24-32 Brain Retina + + Stage 32-40 Brain Retina + + Figure Summary of the regulatory code that control the entire expression of olSix3.2 Summary of the re...

Ngày tải lên: 14/08/2014, 07:22

... Kawaji H, Kasukawa T, Fukuda S, Katayama S, Kai C, Kawai J, Carninci P, Hayashizaki Y: CAGE Basic/Analysis Databases: the CAGE resource for comprehensive promoter analysis Nucleic Acids Res 2006, ... an integrated graphic development interface and tools for automatic SQL script generation and data exchange The wide array of PAZAR hostable datasets contains a great heterogeneity...

Ngày tải lên: 14/08/2014, 08:20

... example of how CRM finding can precede motif-finding in cis-regulatory analysis, rather than rely on prior knowledge or discovery of the motifs A thorough investigation of this claim, using many motif ... level of similarity in terms of the collection of binding sites present within, and this similarity may be the basis for their computational discovery ab initio T...

Ngày tải lên: 14/08/2014, 08:20

... locate and validate candidate cis- regulatory elements for developmental control genes that are ancient in origin and conserved in evolution 1.1 Cis- Regulatory Elements Cis- regulatory elements ... methods to locate and validate cis- regulatory elements 17 1.5 Genomics era methods to locate and validate cis- regulatory elements ……20 1.6 In silico predic...

Ngày tải lên: 14/09/2015, 08:40

... an effort to develop an effective extraction method for bioflocculants from the microbial cell surface Materials and Methods Activated sludge samples Activated sludge samples were collected from ... was the most effective extraction method for activated sludge However, cell disruption is not effective for the isolation of bioflocculants Thus, NaOH extr...

Ngày tải lên: 05/09/2013, 09:08

... to the bus, which the bus driver owns All functions look alike to a bus driver See Figure Figure Generic bus driver model In this model, the bus driver discovers hardware functions first, then ... • A bus driver does not load a driver for a function not currently attached to the bus Figure Generic bus driver model when two functions are contain...

Ngày tải lên: 07/10/2013, 00:20

... Marketing and Business Marketing Associations Jeff frequently speaks on customer satisfaction topics and has written and presented six papers on customer satisfaction, performance improvement and improving ... improvements (Israel, 1994) The types of customer surveys most often used for measuring customer satisfaction include general customer satisfaction tracking...

Ngày tải lên: 18/10/2013, 12:15

... 11 Analytical Methods for Monitoring Biodegradation Processes oriented, and not much attention was paid to the identification of environmental requirements for, and testing of, biodegradable polymers ... available for studying biodegradation processes have been reviewed in detail by Andrady [13, 14]: 1) 2) 3) 4) monitoring monitoring monitoring monitoring accumulati...

Ngày tải lên: 25/10/2013, 08:20

... use these sensors The report is organized in chapters Part I: Sensors for Mobile Robot Positioning Page Sensors for Dead-reckoning Heading Sensors Active Beacons Sensors for Map-based Positioning ... equation for minimal slippage is [Holland, 1983] A r' = B r Page 18 Part I: Sensors for Mobile Robot Positioning Chapter 1: Sensors for Dead Reckoning Figu...

Ngày tải lên: 12/12/2013, 21:16

... use these sensors The report is organized in chapters Part I: Sensors for Mobile Robot Positioning Page Sensors for Dead-reckoning Heading Sensors Active Beacons Sensors for Map-based Positioning ... K2A Navmaster robot (adapted from [Holland, 1983]) Part I: Sensors for Mobile Robot Positioning Chapter 1: Sensors for Dead Reckoning The dead-reckoning c...

Ngày tải lên: 16/12/2013, 14:15

... The Andrew Autogyro Model 3ARG (Courtesy of [Andrew Corp].) 44 Part I Sensors for Mobile Robot Positioning Table 2.1: Selected specifications for the Andrew Autogyro Navigator (Courtesy of [Andrew ... suitable for mobile robot applications In this section we introduce two such systems 2.3.6.1 The Andrew “Autogyro" Andrew Corp [ANDREW] offers the low-cost Autogyro, shown in F...

Ngày tải lên: 22/12/2013, 20:16

... deals with the sensors used in mobile robot positioning, and Part II discusses the methods and techniques that make use of these sensors Mobile robot navigation is a very diverse area, and a useful ... 7KH8QLYHUVLW\RI0LFKLJDQ Where am I? Sensors and Methods for Mobile Robot Positioning by J Borenstein , H R Everett2, and L Feng3 Contributing authors: S...

Ngày tải lên: 22/12/2013, 20:16