Molecular evolution of the mammalian epiblast

... regions of Pou5f1, Sox2, and Nanog in the proto-eutherian mammal I hypothesize that some of these molecular changes contributed to the uniqueness of the eutherian mammal preimplantation embryo The ... The focus of my thesis is on identifying the molecular changes that have led to the evolution of the RoE The most interesting molecular changes are those that...

Ngày tải lên: 11/09/2015, 10:06

... diversity (Shannon's Figure intensity and distribution of positively selected sites in the C2, V3 and C3 regions along the course of HIV-2 infection Frequency, Frequency, intensity and distribution of ... evolution of the HIV-2 env gene In the present study we analyze, for the first time, the molecular evolution of the env C2V 3C3 regions...

Ngày tải lên: 13/08/2014, 05:21

... determine intraspecies polymorphisms in the coding sequence (exons and 3) of the canine leptin gene and the detection of a mutation which occurred in the course of evolution in selected species of ... polymorphisms in the coding sequence of the gene [12] Diversity of the leptin gene was studied in 578 A Chmurzynska et al Table II Some polymorphis...

Ngày tải lên: 14/08/2014, 13:22

... between the fraction of introns containing TEs and median length of introns (Figure 2c), implying that TE insertions have played a role in the evolution of intron size Previous analysis of human and ... (total of 98,695 introns) for TE insertions to determine the percentage of TE-containing introns (Figure 2a) The fraction of the introns that contain TEs in...

Ngày tải lên: 09/08/2014, 20:22

... origin and molecular features of the novel human Tlymphotropic virus type revealed by complete genome analysis J Virol 2006, 80:7427-7438 Lemey P, Pybus OG, Van Dooren S, Vandamme A-M: A Bayesian ... despite the identification of other novel STLVs in this region [9,10,22] Nonetheless, the inability to find "STLV- 4" may be due to sampling and screening biases i...

Ngày tải lên: 13/08/2014, 05:21

... haplotype in the zone with the QTL was conditional to the transmission of the QTL Transmission of the QTL was conditional on the phenotype of the offspring and on the QTL genotypes of the parents In ... significantly lower than the one from markers in QTL zones in lines and 2, and the opposite was observed in line It has to be noted t...

Ngày tải lên: 14/08/2014, 13:21

... profiling of the ring gland The ring gland contained the adipokinetic hormone (AKH; pQLTFSPDWa), the AKH processing intermediate pQLTFSPDWGK, myosuppressin (MS), corazonin, corazonin3-11, the ... by the same amino acid in others The high Danp of 1.69 at position from the carboxyl terminus is again caused by the carboxy-terminal difference RFa and RWa between the sNPF...

Ngày tải lên: 14/08/2014, 20:22

... warmer, thereby preventing freezing and accelerating surface “weathering” Except for Oxygen, almost all of the Earth s atmosphere today Evolution of the Earth Process and Equation” its Atmosphere ... to the appearance☻ of primitive one-celled aquatic organisms which could survive in the oceans Life on Earth had begun, despite its inhospitable atmosphere! Evol...

Ngày tải lên: 04/04/2013, 10:51

... (2001) Roles of ¨ the heat shock transcription factors in regulation of the heat shock response and beyond FASEB J 15, 1118–1131 Fujimoto M & Nakai A (2010) The heat shock factor family and adaptation ... In accordance with the fundamental role of HSF1 in the heat shock response, the requirement of HSF1 and HSF4 in development of the lens and olfa...

Ngày tải lên: 18/02/2014, 04:20

... compares the studied network with randomized versions of it with the same size and degree distribution The so-called Z-score quantifies the difference between the studied network and an ensemble of randomized ... functions, and topological features retain functionality and phylogeny However, the nature of the connections between these factors needs to be underst...

Ngày tải lên: 19/02/2014, 07:20

... additional amino acid residues are also found in the DNases I of amphibians [19] As in amphibian DNases I, the insertion of an additional amino acid residue into the shark enzymes may be essential ... (snake) and Osteichthyes (carp) enzymes were tested for crossinhibition of activity, all five antibodies were ineffective against the shark DNase I, indicating that, from an i...

Ngày tải lên: 19/02/2014, 16:20

... role of a normal crystallin and may instead have a separate function The expression of cN in the retina is particularly interesting There is evidence for expression of cS in the retina and cornea, ... part of a suite of molecular adaptations in the eye in the human lineage In addition to the evolution of cN and cS crystallins, even more specialization...

Ngày tải lên: 19/02/2014, 17:20

... AJ344 360 AJ431378 AJ297738 2258 2283 22 36 2271 2209 2082 65 6 65 9 67 3 66 8 68 5 65 3 74.44 73.93 75.91 74.75 77.74 73.74 5.44 5.57 5 .68 6. 18 5.79 6. 16 0 .66 0.92 1.07 0.89 1.89 1.13 · · · · · · 10)9 ... function, structure and evolution of myriapod hemocyanins is sparse S coleoptrata hemocyanin is a 36- mer with four subunit types The hemocy...

Ngày tải lên: 20/02/2014, 11:20

... has already established Of two possible dimeric structures of LPL, the head-tohead and the head-to-tail models, the studies of the chimeric proteins of hepatic lipase and LPL and the tandem repeat ... (Fig 4A and B, 5) The lipase activity of the K413A mutant is similar to that of wild type LPL, whereas the esterase activity is reduced to 60% of t...

Ngày tải lên: 21/02/2014, 15:20