Genomic analysis of metallothionein expression in breast carcinogenesis

... Metallothionein- 2A silencing In Proceedings of the AACR 101st Annual Meeting 17-21 April 2010, Washington DC, USA Lai Y, Koo CY, Yip GW, Bay BH Over -expression of Metallothionein- 2A isoform increases ... transformation of breast tissues Table Functional significance of MT isoforms in breast cancer MT Isoforms MT-1A Expression Level in Cells Low Expression Level in...

Ngày tải lên: 11/09/2015, 10:03

... be one of the causes of high expression of the drug-metabolising enzyme CYP1B1 in cancerous tissues [14] Finally, as a tumor suppressor in breast cancer cells, miR-17-5p regulates breast cancer ... Ras-GAP binding proteins (G3BP) Oncogene 2007, 26(29):4209-4215 27 French J, Stirling R, Walsh M, Kennedy HD: The expression of Ras-GTPase activating protein SH3 domain-bind...

Ngày tải lên: 10/08/2014, 10:20

... and plateau, and cut to match the surface area of the condyle The areas of India ink staining were outlined using a permanent marker Tracings of the India ink-stained tibial and femoral condyles ... assessments The lamina splendens was not disrupted in any location based on lack of India ink staining, indicat- ing that AC surface integrity was maintained for two weeks i...

Ngày tải lên: 20/06/2014, 00:20

... identify gene expression patterns among the study samples As in the JDM study, a striking increase in the expression of a group of genes previously reported to be induced by IFN was observed in about ... [18] The microarray assay used (Panorama Cytokine Gene Array membranes; Sigma Genosys, Inc) included 375 genes enriched in cytokines, chemokines, cell surface Available on...

Ngày tải lên: 09/08/2014, 01:23

... Cite this article as: Jain and Chattopadhyay: Analysis of gene expression in response to water deficit of chickpea (Cicer arietinum L.) varieties differing in drought tolerance BMC Plant Biology ... internal recycling of CO(2) by pods of chickpea (Cicer arietinum L.) subjected to water deficits J Exp Bot 2001, 52(354):123-131 22 Ahmad F,...

Ngày tải lên: 12/08/2014, 03:21

... GO analysis [32] Ca+2 in fiber initials The differential expression of calmodulin and calmodulin binding proteins indicated that calcium may play a role in fiber initiation The distribution of ... the expression profiling data by identifying an increase in protein biosynthesis in fiber initials and cell wall remodeling in elongating fibers consistent with previously...

Ngày tải lên: 12/08/2014, 05:20

... 10.1186/ar3062 Cite this article as: Kerachian et al., New insights into the pathogenesis of glucocorticoid-induced avascular necrosis: microarray analysis of gene expression in a rat model Arthritis ... vessels of the femoral head In fact, the vascular hypothesis (regional endothelial bed dysfunction) appears to be relevant in the pathogenesis o...

Ngày tải lên: 12/08/2014, 14:22

... hybridization interactions Figure Profile of microRNA expression in the developing mouse brain Profile of microRNA expression in the developing mouse brain (a) Relative expression levels for the 66 microRNAs ... perfectly complementary to the microRNAs [33-38] Determining spatial and temporal patterns of microRNA expression should yield insight into the b...

Ngày tải lên: 14/08/2014, 14:21

... any prolonged agonal conditions, however, death itself may alter gene expression patterns in postmortem human brains Study of expression levels of 14 genes in human brain autopsy and biopsy samples ... significantly increased after death, while the expression of genes involved in protein biosynthesis, rRNA processing, organelle organization and biogenesis and...

Ngày tải lên: 14/08/2014, 16:20

... Mersinias V: DNA microarray-based analysis of gene expression in Streptomyces coelicolor A3(2) and Streptomyces lividans In PhD thesis University of Manchester Institute of Science and Technology, ... operons in E coli and the orthologous operons in S coelicolor (defined as containing at least one equivalent gene, yielding a total of 15 pairs matched by gene nam...

Ngày tải lên: 14/08/2014, 16:21

... grade invasive Colorectal adenoma UBC Squamous cell lung carcinoma Papillary thyroid carcinoma TC Lung adenocarcinoma Myeloma Papillary thyroid carcinoma CT T−cell lymphoma PRCC subtype Early ... adenoma Advanced HCC Lung adenocarcinoma UBC Papillary thyroid carcinoma FV T−cell lymphoma CRCC Myeloma Early stage HCC Papillary thyroid carcinoma TC Papillary thyroid carcinoma CT UBC low grade UB...

Ngày tải lên: 14/08/2014, 20:22

... activation of the ‘profemale’ Wnt signaling pathway In order to understand the role of the brain in the sex VIII change process, a microarray analysis was also carried out on the brain of adult ... on the gonadal maturation stage Long-term treatment of GnRH could also promote the development of spermiating testis in juvenile seabass To test the hypothesis...

Ngày tải lên: 09/09/2015, 11:21

... identification of specific pathways whose gene expression is coordinately regulated in association with obesity, defined genomic regulatory loci controlling the expression of these genes, and novel genes ... for genes involved in insulin signaling Two hundred and fortyfour gene sets were obtained by querying all the pathways available at Biocarta [16] The latter set comprises...

Ngày tải lên: 14/08/2014, 14:21

... 8.95) These cut-offs are arbitrary and chosen because they resulted in about half of the genes falling into 'average' gene expression and the remainder of the genes falling roughly equally into ... and that inclusion of these genes in the analysis may obscure an effect Thus, we repeated the analysis with the 500 genes with the strongest differences in...

Ngày tải lên: 14/08/2014, 20:22

... Tell-tale signs of breast cancer other than presence of lumps include thickening in an area of the breast, change in the size or shape of the breast, dimpling of the skin, change in shape of the nipple, ... impact on breast cancer has not been elucidated Furthermore, there are ten functional isoforms in human, with MT -2A being the most abundant isoform in...

Ngày tải lên: 14/09/2015, 14:08