Design, synthesis and biological studies of coumarin based probes and tetrahydrolipstatin analogs 1
Design, synthesis and biological studies of coumarin based probes and tetrahydrolipstatin analogs 1
... NBD-sarcosine (1. 14) and 7-dimethylamino coumarin- 4-acetic acid (1. 15).9 R O R O MeO O O O H O O O O O O O O O 1. 12 R = OAc 1. 16 R = 1. 14 1. 17 R = 1. 15 O2 N 1. 13 R = OAc 1. 18 R = 1. 14 1. 19 R = 1. 15 N N ... F Eur Pat 19 98, EP08479 91 13 Paterson, M J.; Jovanovic, A Arkivoc, 2 010 , 10 , 11 -16 14 Nielsen, O.; Burchardt, O Synthesis, 19 91, 819 -8 21 15 Dey, B...
Design, synthesis and biological studies of coumarin based probes and tetrahydrolipstatin analogs
... 125.7577890 MHz DATE_d : DECNUC : off NS 39.9955 39.8279 39.7551 39.6968 39.6603 39.4927 39.3324 39.1648 38.9972 38.8514 38.7057 BF1 : 137 Oct 23 2006 NUCLEUS : off PULPROG : zgpg30 SFO1 : 125.7709936 ... Parameters *** O sg1023~1 : *** Acquisition Parameters *** O 2.19 Oct 23 2006 : off NS O : DECNUC N : 125.7577890 MHz DATE_d : 57 off PULPROG : N H BF1 NUCLEUS : N H (1) N O : PROCNO 34.0345...
Aircraft Design: Synthesis and Analysis - part 1 doc
... the DC- 9 -1 0, a 77,000 lb, 80 passenger airplane grew into a DC- 9-2 0, then the -3 0, -4 0, -5 0, -8 0 then on to the MD-80 and MD-90 series The MD-90 weighs as much as 17 2,000 lbs and can carry 15 0 ... development of the DC-9 and DC -1 0 , and taught at Stanford University after that for 20 years To a large extent, this is his course Instructions This version o...
design, synthesis, and biological evaluation of new anti-cancer nitrogen-containing combretastatins and novel cysteine protease inhibitors for the treatment of chagas
... Evaluation of New Anti-cancer Nitrogen-Containing Combretastatins and Novel Cysteine Protease Inhibitors for the Treatment of Chagas Rogelio Siles Mentor: Kevin G Pinney, Ph.D In an effort to combat ... Derivatives of Combretastatins A-1 and A-4 66 Synthesis of Cold Precursors of Radio-labeled Combretastatins CA-1 and CA-4 70 Synthesis of OXi800...
Design, synthesis and biological evaluation of inhibitors of flavivirus NS2B NS3 protease
... the thesis involves the design, synthesis and biological evaluation of inhibitors of Dengue and West Nile virus NS2B- NS3 protease For the design of dengue NS2B- NS3 protease inhibitors, we were inspired ... DEN2 NS2b- NS3 protease 60 Chapter 4: Synthesis and biological evaluation of small molecule inhibitors of West Nile Virus NS2B/ NS3 P...
Design, synthesis and applications of Metal Organic Frameworks
... Assembly of metal organic frameworks (MOFs) by the copolymerization of metal ions with organic linkers to give (a) flexible metal bipyridine structures with expanded diamond topology and (b) rigid metal carboxylate ... MOFs—namely synthesis of new ligands to expand the library of molecular building blocks for constructing MOFs as well as synthesis of MOFs from those...
DESIGN, SYNTHESIS AND STUDY OF DNA-TARGETED BENZIMIDAZOLE-AMINO ACID CONJUGATES
... Research Integrity and Copyright Disclaimer Title of Thesis/Dissertation: Design, Synthesis and Study of DNA-Targeted Benzimidazole-Amino Acid Conjugates For the degree of Master of Science Choose ... http://www.purdue.edu/policies/pages/teach_res_outreach/c_22.html DESIGN, SYNTHESIS AND STUDY OF DNA-TARGETED BENZIMIDAZOLE-AMINO ACID CONJUGATES A Th...
design, synthesis and photophysics of fluorescence turn-on conjugated polymer chemosensors
... Department of Biological Sciences iii ABSTRACT This dissertation explores the synthesis, characterization, and application of conjugated polymers as fluorescence turn-on chemosensors A series of conjugated ... Experimental Section 34 2.3 Results and Discussion 40 2.3.1 40 Synthesis and Characterization xi Sonogashira coupling 40 Synthesis of monomers 43 Synthesis...
design, synthesis, and characterization of polymeric materials for uses in energy storage applications
... focuses on the design, synthesis, and characterization of polymeric materials for energy storage applications, which include small molecule electrolyte additives, solid polymer electrolyte, and gel ... numbers of other synthetic polymers were developed and commercialized in response to the growing need for new materials in the automotive and aerospace indu...
DESIGN, SYNTHESIS AND PROPERTIES OF METAL COMPLEXES AND COORDINATION POLYMERS FOR 2+2 PHOTO CYCLOADDITION REACTIONS
... representation of transformation of 1D CP 1-22 into 3D MOF through photo cycloaddition reaction Figure 1- 11 PSM of 3D MOF through solid state [2+2] photo 1-23 cycloaddition reaction Figure 1- 12 Photo cycloaddition ... PSM of 3D MOF through solid state [2+2] photoreaction 1.6.3 Photoreactivity in metal complexes using monodentate ligand Compared to the bidentate ligan...
Development of biosensor and electrochemical studies of carbon based materials
... DEVELOPMENT OF BIOSENSOR AND ELECTROCHEMICAL STUDIES OF CARBON- BASED MATERIALS CHONG KWOK FENG (B.Sc Universiti Teknologi Malaysia) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY ... extraordinary electrochemical properties of diamond for the construction of a robust and sensitive biosensor VIII In the third results section of this thesis (Chapte...
Design, synthesis and characterization of smart surfaces and interfaces
... solution of (a) the pristine PVDF, and the PVDF-gP4VP copolymers of bulk graft concentrations ([-4VP-]/[-CH2CF2-]bulk ratios) of (b) 0.038, (c) 0.068 and (d) 0.083 Figure 3.8: Effect of pH of the ... (a) UV-visible absorbance of aqueous solutions of PDMAPS of different concentrations as a function of temperature (b) UV-visible absorbance of aqueous solutions of PDMAP...
Tài liệu Báo cáo khoa học: Structural and functional studies of the human phosphoribosyltransferase domain containing protein 1 docx
... S103 G145/D137 Y 112 D2 01/ 193 L75/67 G145/D137 E1 41/ 133 K173 /16 5 R207 /19 9 G77/69 D142 /13 4 G197 /18 9 Fig Superposition of PRTFDC1 with HPRT-ImmGP (Protein Data Bank code: 1BZY) (A) Residues in the ... Welin et al Studies of the human PRTFDC1 B A PRTFDC1 25 HPRT 20 10 00 0.2 800 600 400 0 .1 200 –50 50 10 10 50 10 015 0 200 250 S 200 –50 250 50 12 00 10 0 15 0 [H...
Báo cáo toán học: " Synthesis and anti-HSV-1 evaluation of new " docx
... Synthesis and anti-HSV-1 evaluation of new 3H-benzo[b]pyrazolo[3,4-h]1,6-naphthyridines and 3H-pyrido[2,3-b]pyrazolo[3,4-h]-1,6- naphthyridines Alice M R Bernardino1, Alexandre R Azevedo1, ... We previously reported the synthesis, SAR studies, and evaluation anti-HSV-1 activity of 3H-benzo[b]pyrazolo[3,4h]-1,6-naphthyridines In the course of our search for new 1,6-n...