Mechanism of action and binding mode revealed by the crystal structures of key enzymes in plants sugar metalbolic pathway

... view of the S6P binding site Superimposition of F6P-SPS and S6P-SPS complexes Ten docked models of UDP interacting with the binding residues of H orenii SPS Ten docked models of ADP interacting ... substrate binding site of SPS contoured at a level of 3.0σ (a) Molecular surface of SPS showing the distinct two domains separated by a large substrate binding cleft (b) Close-up view of the F6P binding ... using 0.01-0.02 mM of the SPS in the sample cell and 0.1-0.2mM of F6P in the injector (Figure 2.9) Injection volumes of 4-5 µL each were used and the number of injections 24 was 60 The heat of...

Báo cáo y học: "Wound healing and inflammation genes revealed by array analysis of ''''macrophageless'''' PU.1 null mice" ppt

... microarray investigations of genes upregulated in fibroblasts in response to serum exposure Cluster analysis of these results hints at the roles of hundreds of genes by the similarity of their ... significantly reduced in PU.1 null wounds, as revealed by RNase protection analyses [6] In this study we use Affymetrix GeneChip analysis of mRNAs collected at various time points after wounding of wild-type ... back skin of 2-day-old neonatal PU.1 null mice and their wildtype littermates Each time-matched pair (PU.1 null and wildtype) were chosen from the same litter to reduce the possibility of differential...

ENGLISH ADVERBS OF MANNER AND TYPICAL ERRORS MADE BY THE STUDENTS AT LE HONG PHONG SPECIALISED SECONDARY SCHOOL, NAM DINH CITY

... What are the formation and uses of English adverbs of manner? What are the typical errors in using adverbs of manner made by students at Lê Hồng Phong specialised secondary school? What are the ... aims at analyzing typical errors made by the students at Lê Hồng Phong specialised secondary school, Nam Dinh city in using English adverbs of manner with the hope to improve teaching and learning ... VIETNAM NATIONAL UNIVERSITY, HANOI COLLEGE OF FOREIGN LANGUAGES POST GRADUATE DEPARTMENT PHẠM KIM ANH ENGLISH ADVERBS OF MANNER AND TYPICAL ERRORS MADE BY THE STUDENTS AT LE HONG PHONG SPECIALISED...

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Tài liệu Báo cáo khoa học: Loose interaction between glyceraldehyde-3-phosphate dehydrogenase and phosphoglycerate kinase revealed by ﬂuorescence resonance energy transfer–ﬂuorescence lifetime imaging microscopy in living cells doc

... of the interaction between GAPDH and PGK chimeric proteins linked to cerulean [16] or citrine [17], a FRET pair, in living cells FRET imaging of interaction between GAPDH and PGK Results and Discussion ... distances between the Nterminal amino acids of subunits O and P, subunits O and Q and subunits O and R are shown (B–D) FLIM analysis of the interaction between cerulean–GAPDH and citrine–GAPDH in living ... expressed GAPDH–citrine (chimeric protein with N-terminal GAPDH and C-terminal citrine) and citrine–GAPDH (chimeric protein with N-terminal citrine and C-terminal GAPDH) were localized in the cytoplasm...

AN IMPACT EVALUATION OF EDUCATION, HEALTH, AND WATER SUPPLY INVESTMENTS BY THE BOLIVIAN SOCIAL INVESTMENT FUND pptx

... Lavy and others 1996, Mwabu and others 1993), and drinking water (Brockerhoff and Derose 1996, Lee and others 1997) The main conclusions of the study are as follows Although the social fund improved ... Because the worst-off and best-off schools were excluded from the randomization and the sample, the study’s findings on the impacts of the sif cannot be generalized to all schools 246 the world bank ... because of financial constraints Thus by the time of the follow-up survey some clinics had received an interven- Newman and others 253 tion and some had not Thanks to the financing from the German...

A survey of technology thinkers and stakeholders shows they believe the internet will continue to spread in a “flattening” and improving world. There are many, though, who think major problems will accompany technology advances by 2020 doc

... from about 1,000 people were amassed The early 1990s predictions are available in a searchable database online at the site Imagining the Internet: A History and Forecast and they are also the basis ... IBM and the Internet Engineering Task Force “Random acts of senseless violence and destruction will continue and expand due to a feeling of 21st century anomie, and an increasing sense of lack of ... privacy remains important, so I tend to think that we will find ways to limit the invasion of it Data mining techniques and other kinds of analysis will make the globe more similar to a small town...

ASSESSMENT OF THE ENVIRONMENTAL AND SOCIAL IMPACTS CREATED BY THE VLRC INDUSTRIAL RUBBER PLANTATION AND PROPOSED ENVIROMENTAL AND SOCIAL PLANS ppt

... assessment of the environmental and social impacts created by the rubber plantation project (the Project) of the Viet-Lao Rubber Company (VLRC) in Champasack province, in the south of Laos It is ... for the development of a rubber plantation Following the approval by the People Committee of the Province of Champasack, on the 27th of October 2004, the note 120 of the People Committee of the ... affected by the Project Loss of land and access to land The 33 villages impacted by the Project were found to have lost 83% of their agricultural lands This major loss of land, and the loss of access...

Báo cáo y học: " Strong functional patterns in the evolution of eukaryotic genomes revealed by the reconstruction of ancestral protein domain repertoi" doc

... and Godzik: Strong functional patterns in the evolution of eukaryotic genomes revealed by the reconstruction of ancestral protein domain repertoires Genome Biology 2011 12:R4 Submit your next manuscript ... http://genomebiology.com/2011/12/1/R4 extinct domains, domains not present or detected in any of the analyzed genomes nor as yet unidentified domains Since the Pfam database does not yet cover the complete protein domain universe ... seeks to minimize domain losses, to reconstruct the Pfam domain repertoire of ancestral eukaryotes [33-38] (Figure 2) The evolution of most eukaryotic groups is dominated by protein domain losses...

báo cáo khoa học: " The function and mechanism of COX-2 in angiogenesis of gastric cancer cells" pdf

... types of human cancer However, the mechanism of COX-2 in angiogenesis remains unclear In this study, the data showed that down-regulation of COX-2 could significantly inhibit the in vitro and in ... et al.: The function and mechanism of COX-2 in angiogenesis of gastric cancer cells Journal of Experimental & Clinical Cancer Research 2011 30:13 Acknowledgement This study was supported in part ... proliferation of SGC7901 cells (Figure 2A) As shown in Figure 2B, down-regulation of COX-2 might inhibit the malignant growth of SGC7901 cells in vivo Down-regulation of COX-2 inhibited angiogenesis of gastric...

báo cáo khoa học: " Insight into the early steps of root hair formation revealed by the procuste1 cellulose synthase mutant of Arabidopsis thaliana" doc

... use of the procuste1 (prc1-1) cellulose deficient mutant of Arabidopsis to probe the influence of cell wall structure in modulating root hair formation The Arabidopsis prc1-1 is mutated in the cellulose ... stimulate root hair formation in wild-type and can result in the restoration of hair formation in rhd6 [6] This raised the question of whether the partial restoration of hair formation in rhd61 by prc1-1 ... of trichoblasts forming a root hair was less than half that of either the wild-type or prc11 single mutant roots (Fig 5E) The morphology of the hairs that formed in the rhd6-1/prc1-1 double mutant...

Dual activation of estrogen receptor a and aryl hydrocarbon receptor by the prenylflavone, icaritin restrict breast cancer cell growth and destabilize estrogen receptor a protein

... Despite the availability of therapies targeting estrogen and growth factor signaling pathways, the incidence and mortality of breast cancers have not decline at the same rate as other major causes of ... 36 1.8 Icaritin and cancer cell proliferation 1.8.1 Icaritin and cancer cell proliferation Herba Epimedii is officially listed in China as an herb that prevents the growth of cancer and has been ... therapy in postmenopausal hormone therapy and recurrence of breast cancer Table shows the risk of breast cancer recurrence in breast cancer survivors after hormone replacement therapy [Figure adapted...

Báo cáo khoa học: Conservation of the egg envelope digestion mechanism of hatching enzyme in euteleostean ﬁshes pot

... result of the formation of e-(c-glutamyl) lysine cross-links between subunit proteins of the envelope, mainly between inner layer subunit proteins [10] At the time of hatching of the embryo, the inner ... envelope One of the goals of the present study was to determine the cleavage sites of hatching enzyme on egg envelope proteins The natural substrate of hatching enzyme is fertilized egg envelope ... observed in rainbow trout hatching liquid (Fig 7A, *4) The sequence analysis revealed Fig The conservation of the egg envelope digestion mechanism of hatching enzyme in euteleosts (A) Tricine-SDS...

Báo cáo khoa học: Improvement of a monopartite ecdysone receptor gene switch and demonstration of its utility in regulation of transgene expression in plants pdf

... (forward, 5¢-AAG GCT TAC CAC GAG CAG CTA TCA-3¢; reverse, 5¢-ACA GGC CAT GTA CTT TCC GTG TCT-3¢) and tobacco (forward, 5¢-ATG AGA GAG TGC ATA TCG AT-3¢; reverse, 5¢-TTC ACT GAA GGT GTT GAA-3¢) a- tubulinspeciﬁc ... VGCfEVY switch in regulating the expression of a zinc ﬁnger protein transcription factor isolated from Arabidopsis thaliana (AtZFP11) in both Arabidopsis and tobacco plants Results Selection of CfEcR ... used in several inducible gene regulation systems to control transgene expression in mammalian cells, transgenic animals, and plants [39] The EcR gene switches described to date are mostly in monopartite...

Designation: C 51 – 00a - Lime and Limestone (as used by the Industry)1 pptx

... sedimentary rock consisting chieﬂy of calcium carbonate or of the carbonates of calcium and magnesium Limestone may be of high calcium, magnesian, or dolomitic (1) dolomitic limestone limestone containing ... a by- product of materials other than limestone, for example, Ca(OH)2 formed by acetylene generation from calcium carbide (CaC2), water treatment sludges, etc DISCUSSION The chemical forms of calcium ... purposes lime putty the product obtained by slaking quicklime with water according to the directions of the manufacturer or by mixing hydrated lime and water to a desired consistency limestone an...

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