Novel biology driven bioinformatics methods in cancer genomics

... genes involved in collagen binding, including several isoforms of collagen; 3) Basal epithelial cell type/ERbreast cancer: Keratin 5, Keratin 17, and SFRP1 Keratin has been used a marker to stain ... Studies of Cancer Genomics 13 2.1 Cancer 13 2.2 microarray Application in Cancer Research 15 2.3 Novel data analysis methods to refine the molecular profiling of cancer ... the...

Ngày tải lên: 11/09/2015, 09:04

... and training of personnel for cancer research The publications of the Agency are intended to contribute to the dissemination of authoritative information on different aspects of cancer research ... (1980) Statistical Methods in Cancer Research Volume I - The Analysis of CaseControl Studies, Lyon, International Agency for Research on Cancer (IARC Scientific Publications N...

Ngày tải lên: 22/03/2014, 17:20

... set, data cleansing and preprocessing, data reduction and projection, choosing data mining task, choosing data mining algorithm, data mining, interpreting the mined patterns and consolidating ... livestock genomics for integrative data analysis following the principles of data mining and knowledge discovery and (ii) demonstrating the application o...

Ngày tải lên: 25/11/2015, 13:26

... [80] and induces T -cell activation DPIV family in cancer and cell biology Fig Features of the effects of DP upon T -cell activation ⁄ function Cell- surface CD26 ⁄ DPIV interacts with adenosine ... activation of DPIV in hepatic carcinoma cell lines induces cell apoptosis, but DPIV in Jurkat T cells conversely plays a role in cell survival [161] DPIV expression...

Ngày tải lên: 06/03/2014, 09:22

... A novel serine protease in various cancer cells serine protease, spinesin ⁄ TMPRSS5, which is localized at synapses [6] Motopsin (PRSS12) is a mosaic serine protease, with a kringle domain and ... RT-PCR analyses revealed that prosemin is expressed in various kinds of cancer cell lines and in clinical samples of ovarian carcinomas The characte...

Ngày tải lên: 16/03/2014, 23:20

... serum protein features of a number of cancers in the near future [47] Translational research in breast cancer Breast cancer Breast cancer is the most common malignancy among women in the Western ... Danish Centre for Translational Breast Cancer Research (DCTB), to fight breast cancer DCTB hosts scientists working in various areas of preclinical cancer res...

Ngày tải lên: 30/03/2014, 15:20

... embryos, in which maternal dorsal determinants have been inactivated or removed, have been an effective tool for analyzing From: Methods in Molecular Biology, Vol 127: Molecular Methods in Developmental ... From: Methods in Molecular Biology, Vol 127: Molecular Methods in Developmental Biology: Xenopus and Zebrafish Edited by: M Guille © Humana Press Inc., Tot...

Ngày tải lên: 11/04/2014, 09:52

... bridging protein consisting of the immunoglobulin G (IgG)-binding β2 domain of streptococcal protein G modified by genetic fusion with the positively charged leucine zipper interaction domain (PG-zb), ... III Series: Methods in molecular biology (Clifton, N.J.) ; 303 TP248.25.N35N35 2005 660.6 dc22 2005000473 Preface Increasingly, researchers find themselves involved in discipline-spa...

Ngày tải lên: 04/06/2014, 15:14

... of HERG K(+) channels in firing and release FASEB J 2000, 14(15):2601-10 doi:10.1186/1477-7819-8-113 Cite this article as: Asher et al.: Eag and HERG potassium channels as novel therapeutic targets ... role in prolactin secretion [58] Further investigation of HERG channels in cancer invasion and metastasis revealed that, in addition to the high expression...

Ngày tải lên: 09/08/2014, 03:24