Excluded volume effects in molecular biology and extracellular matrix biochemistry biophysical considerations and molecular modeling

... Crowding influences Intra-cellular Trafficking 6.4 Macromolecular Crowding on Protein-folding and Stability 6.5 Macromolecular Crowding Effects on Protein-Aggregation 6.6 Macromolecular Crowding Effects ... frequently increasing the binding strength by at least an order of magnitude (Wilf & Minton, 1981) 6.4 Macromolecular Crowding on Protein-folding and Stability Crowding influences...

Ngày tải lên: 11/09/2015, 09:02

... H, Andoh A, Makino J, Shimada M, Tasaki K, Araki Y, Bamba S, Hata K, Fujiyama Y, Bamba T: Interleukin-17 stimulates chemokine (interleukin-8 and monocyte chemoattractant protein-1) secretion in ... Finally, data from IL-1 7–/ – and IL-17R– /– mice indicate that this cytokine is also involved in a variety of other T cell dependent events For example, delayed type hype...

Ngày tải lên: 09/08/2014, 01:24

... phosphorylation in yeast Nature 2005, 438: 679-684 23 Yip KY, Yu H, Kim PM, Schultz M, Gerstein M: The tYNA platform for comparative interactomics: a web tool for managing, comparing and mining multiple ... proteins and in DNA binding for AR and hydrophilicity-sensitive proteins In addition, charge-sensitive proteins showed an enrichment in transferase activity and MlogP...

Ngày tải lên: 09/08/2014, 22:24

... Approximately185 and/ or tissues, and that background and stochastic or transient effects may be confounding factors Large-scale studies of gene-dosage effects in Down- syndrome fetuses and trisomic ... They used RNA from four normal and four Down- syndrome cerebrums and from four normal and four Down- syndrome- derived astrocyte cell lines cultured from cerebral...

Ngày tải lên: 14/08/2014, 14:21

... MECHANICAL CHARACTERIZATION OF BIOPOLYMER AND THE EFFECTS OF MECHANICAL PROPERTIES OF EXTRACELLULAR MATRIX ON CELL BEHAVIORS WONG LONG HUI (B.Eng.(Hons.), NTU) A THESIS SUBMITTED FOR THE ... in cell and extracellular matrix interactions The first part of the thesis involved the use of conventional macrorheological technique to uncover the ri...

Ngày tải lên: 09/09/2015, 11:28

... linear (Ohmic) behavior of the current response in the polymer thin film, resulting in electrical conductivity switching behavior and memory effect in the sandwich structure The individual memory ... insulator, bistable electrical conductivity switching (WORM memory and flash memory effects) , and conductor behaviors, when the CNT content in the composit...

Ngày tải lên: 11/09/2015, 09:59

... use mixture models to allow for variability among individuals This allows us to introduce heterogeneity in a biologically meaningful way In the next section, we describe the multistage carcinogenesis ... threshold value may abrupt changes in the system occur Since we consider a late end-point, namely cancer, in a very complicated system, it is not surprising that we obtain in...

Ngày tải lên: 13/08/2014, 16:21

... be involved in recognition of the methylated Lys4 amino group Multidomain organization of LSD1 and its enzymatic activity in the chromatin context Genes coding for LSD1 ⁄ K -demethylase proteins ... protein–protein and DNA–protein interactions [36] The name of this domain derives from its original identification in the proteins SWI3, Rsc8 and Moira, which are ATP-depen...

Ngày tải lên: 16/03/2014, 02:20

Ngày tải lên: 08/08/2014, 14:21