Molecular mechanisms underlying the pathogenesis of nasal polyposis and its response to steroid treatment

... in the session of “Inflammatory Mechanisms in Rhinosinusal Disease”.) iv Molecular mechanisms underlying the pathogenesis of nasal polyposis and its response to steroid treatment Content of the ... through the epithelial defect and the mucosa tends to cover it by migration of the epithelium from the edges 23 of the defect; (iii) the pr...

Ngày tải lên: 10/09/2015, 15:49

... as: Qin and Tian: Exploring the molecular mechanisms underlying the potentiation of exogenous growth hormone on alcoholinduced fatty liver diseases in mice Journal of Translational Medicine 2010 ... mRNA expression HMW adiponectin is the major bioactive isoform of adiponectin, and is responsible for the insulin-sensitizing effects of adiponectin, whil...

Ngày tải lên: 18/06/2014, 16:20

... antithrombins are glycosylated at four of their asparagine molecules; these are of the α isoform The remaining 5–15% of circulating antithrombins, of the β isoform, lack glycosylation at asparagine ... purposes) Interaction of antithrombin with endothelium The affinity of antithrombin (AT) to thrombin and its enzymatic inhibition is increased by binding of AT with t...

Ngày tải lên: 12/08/2014, 23:21

... spatial and temporal resolution In this thesis, I have studied the molecular mechanisms that regulate the determination of the position of the cleavage furrow and the cleavage furrow formation in cytokinesis ... action Inhibit myosin II ATPase activity by binding to myosin II-ADP-Pi Blebbistatin and inhibit the release of the ADP Inhibit actin pol...

Ngày tải lên: 14/09/2015, 14:09

... case of the more general principle of flux minimization It has to be noted, furthermore, that minimization of fluxes in a metabolic system is closely linked to minimization of enzyme levels, because ... protein, protein interactions, enzymes, metabolites) can be used to build up mathematical models of the gene-regulatory, signal-transducing and metabolic network...

Ngày tải lên: 07/03/2014, 15:20

... relation to learning and memory formation requirements Furthermore, the molecular mechanisms underlying the MFs redistribution during learning and memory formation are still under investigation ... hilus and CA3 area, comprise the second synapse of the hippocampal circuit In this trisynaptic model of the hippocampus, based on the observations of th...

Ngày tải lên: 09/09/2015, 18:55

... 5.2.3.1 Fear conditioning training 115 5.2.3.2 Short-term contextual memory and cued memory test 115 5.2.3.3 Retention and extinction of long-term contextual memory and cued memory ... which have been done in this thesis to investigate the underlying mechanisms of learning process and long-term memory formation In part I, two projects have been focused on...

Ngày tải lên: 09/09/2015, 18:55

... symptoms of envenomation and the ultimate severity of a bite depend on the size and species of the snake, the amount and degree of toxicity of the venom injected, Introduction the location of the ... MOLECULAR MECHANISMS UNDERLYING THE BIOCHEMICAL ACTIVITIES OF NAJA SPUTATRIX VENOM CHARMIAN CHER DYI NI B.Sc (Hons) A THESIS SUBMITTED FOR THE DEGR...

Ngày tải lên: 16/09/2015, 08:31

... curves of CHABII and [Phe21] -CHABII at pH 6.5 (b) Thermal unfolding curves of CHABII and [Phe21] -CHABII at pH 4.0 (c) Thermal unfolding curves of [Phe21] -CHABII at pH 4.0 and [Phe21] -CHABII at ... proteins Extensive 32 CD and NMR experiments were performed to characterize the role of His21 in the pH -induced unfolding of CHABII Thermal unfoldin...

Ngày tải lên: 26/11/2015, 12:54

... HANDLED HANDLED 40 35 30 25 20 15 10 C A2 C A2 Figure Effects of handling on MR and GR immunoreactivity in the CA2 region of the hippocampus Effects of handling on MR and GR immunoreactivity ... assay system) Statistical Analysis Data were analyzed by a one-way analysis of variance (ANOVA) with handling as the independent factor Data on learning, body weight and...

Ngày tải lên: 08/08/2014, 21:20

... be of importance in understanding the immune mechanisms in IIMs Taken together, they demonstrate the complexity of involvement of the immune system in these diseases and suggest that both the innate ... concerning the role of T lymphocytes, B lymphocytes, dendritic cells, and other antigen-presenting cells (APCs) in the pathophysiology of IIMs T lymphocytes...

Ngày tải lên: 09/08/2014, 10:20

... components The profile was similar to that induced by a combination of IL-1/TNF, which might indicate the involvement of an inflammatory cytokine-mediated pathway in the observed induction of MMPs by ... multiple MMP mRNAs by S aureus in human dermal and synovial fibroblasts Multiple MMP mRNA profile in dermal and synovial fibroblasts in respo...

Ngày tải lên: 09/08/2014, 08:23

... abnormalities in systemic lupus erythematosus Curr Immunol Rev 2005, 1:61-67 Perl A: Emerging new pathways of pathogenesis and targets for treatment in systemic lupus erythematosus and Sjogren’s syndrome ... regulates mammalian target of rapamycin activity and TCRζ expression in SLE The mammalian target of rapamycin (mTOR) is a serine/ threonine protein kinase a...

Ngày tải lên: 12/08/2014, 14:22

... research in this environment by exploring governance issues relating to the quality of financial reporting and auditing in Singapore In spite of its size, Singapore plays an important role in setting ... to the SES © AAANZ, 2002 200 Jenny Goodwin, Jean Lin Seow / Accounting and Finance 42 (2002) 195–223 an understanding of accounting, auditing and contr...

Ngày tải lên: 06/01/2015, 19:49

... infiltrating leukocytes (neutrophils and macrophages) in the pancreas are the main sources of chemokine production in caerulein-induced acute pancreatitis in mice and the alveolar macrophages, epithelial ... partially associated with the suppression of SP expression in the pancreas and lungs in the condition (Lau and Bhatia, 2006) Despite the cl...

Ngày tải lên: 11/09/2015, 09:09