The structure basis for burkholderia pseudomallei hcp induce

The structure basis for burkholderia pseudomallei hcp induced multinucleated giant cell formation

... pseudomallei induced MNGC formation Moreover, the in situ substitution of these hcp1 residues in B pseudomallei abolishes MNGC formation and Hcp1 secretion Taken together, these data provide structural ... that form the shaft and the needle tip respectively 76,96,97 The contraction of TssA/B is thought to be responsible for their ejection into the extracellular milieu...

Ngày tải lên : 10/09/2015, 09:25

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Tài liệu Lecture 14: The Theoretical Basis for Data Communication: pptx

... us the ratio of two power levels, that is it expresses the gain of the system But some time we want to express the exact output power of a system rather than the gain In that case, we compare the ... dBm signal (10 mW) the noise level has to be less than -20 dBm (10 microW) Shanon Theorem: Mathematical guidelines have been established to determine the maximum theoretical da...

Ngày tải lên : 10/12/2013, 08:15

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Tài liệu Báo cáo khoa học: Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells pdf

... exposure of liver cells to FFAs Interruption of TAG synthesis in conditions of excess availability of SFAs is the key point in the molecular mechanism of SFA-induced lipotoxicity It is suggested ... constitutes the initiating event in the process of lipotoxicity Stearate has to be activated in order to be toxic The ﬁrst enzyme involved in me...

Ngày tải lên : 14/02/2014, 22:20

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Báo cáo khoa học: The structural basis for catalytic function of GMD and RMD, two closely related enzymes from the GDP-D-rhamnose biosynthesis pathway pdf

... Stereoview of the RMD monomer The cofactor-binding domain and the substratebinding domain are shown in aqua and light sand, respectively; the APPR portion of the cofactor (dark gray) and the ligand ... disease and reduced lung function [20] An eight-gene cluster encodes functions for synthesis and export of A-band O polysaccharide [21,22], and contains genes...

Ngày tải lên : 16/03/2014, 01:20

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Báo cáo khoa học: "Natural black pine (Pinus nigra subsp salzmannii) forests of the Iberian eastern mountains: development of the phytoecological basis for their site evaluation *" pptx

... 1992) The total natural populations of this species extend over approximately 380 000 hectares The black pine forests found in the Sistema Ibérico account for two-thirds of the total black pine formations ... 1896), and they provided very accurate descriptions of the main forests of this species When describing black pine woods along the Sistema Ibérico,...

Ngày tải lên : 08/08/2014, 19:21

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Structure basis for molecular recognition of folic acid by folate receptor

... form of folate in circulation is 5-methyl tetrahydrofolate (5-methyl THF) [7] a) b) Figure Chemical structure of folic acid and folate derivatives a) Constitution of folic acid b) Tetrahydrofolate ... crystal structure of FRα -folic acid complex which provided the molecular basis for the high affinity binding Folate receptor is a globular protein which con...

Ngày tải lên : 09/09/2015, 11:28

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Identification of plant as a novel and alternative host model for burkholderia pseudomallei

... Pseudomonas syringae and R solanacearum have been elucidated using Arabidopsis as a plant model (Quirino and Bent, 2003) 3.2 Materials and Methods 3.2.1 Plant Materials 3.2.1.1 Tomato and Arabidopsis ... and can be isolated from rice paddy fields in endemic areas such as Thailand Dharakul and Songsivilai first raised the question of a relationship between B pseudo...

Ngày tải lên : 09/10/2015, 10:49

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Tài liệu Báo cáo khoa học: Kinetic basis for linking the ﬁrst two enzymes of chlorophyll biosynthesis doc

... accelerating the formation and breakdown of the catalytic intermediate, providing a kinetic link between the ﬁrst two reactions of chlorophyll biosynthesis, with the signalling molecule MgP as the common ... Scheme Diagram of the branchpoint of tetrapyrrole biosynthesis, showing the participation of the Mg chelatase H subunit in both the chelatase and m...

Ngày tải lên : 20/02/2014, 02:21

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Đề tài " A five element basis for the uncountable linear orders " doc

... In particular if X is a set of reals of cardinality ℵ1 , then X serves as a single -element basis for the class of uncountable separable linear orders PFA is a strengthening of the Baire Category ... C UNCOUNTABLE LINEAR ORDERS 671 ∗ Conjecture (PFA) [4] The orders X, ω1 , ω1 , C and C ∗ form a ﬁve element basis for the uncountable linear orders...

Ngày tải lên : 06/03/2014, 08:21

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Báo cáo khoa học: Investigations into the ability of an oblique a-helical template to provide the basis for design of an antimicrobial anionic amphiphilic peptide pot

... contribute to the susceptibility of E coli model membranes to the action of AP1 An important determinant of the susceptibility of membranes to a-AMPs is the packing characteristics of the individual ... hypothesis of Tytler et al [48], it may be that insertion of the inverted wedge shape formed by the AP1 a-helix into membranes of E coli leads to the...

Ngày tải lên : 07/03/2014, 12:20

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Báo cáo khoa học: Structural basis for the erythro-stereospeciﬁcity of the L-arginine oxygenase VioC in viomycin biosynthesis docx

... structures of VioC hydrogen bond to the peptide group of Ser158 In addition, the guanidinium group of the l-arginine side chain forms salt bridges to the closely adjoined side chains of the acidic ... by the hydroxyl group of the side chain of Ser224 and the carboxamide group of the side chain of Gln137 Gln137 is suitably oriented to interact with the...

Ngày tải lên : 16/03/2014, 02:20

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Báo cáo khóa học: S-(2,3-Dichlorotriazinyl)glutathione A new afﬁnity label for probing the structure and function of glutathione transferases potx

... partial active enzyme intermediate, and kfast and kslow are A nity labelling of maize GST I (Eur J Biochem 271) 3505 the rate constants for the slow and fast phase of the reaction Analysis was ... B-factors of Met121 at ˚ ˚ the A and B chains are 26.67 A2 and 49.26 A2 , and the ˚ and 79.30 A2 , respect˚ B-factors of S atoms are 38.14 A ively It is the...

Ngày tải lên : 16/03/2014, 16:20

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Báo cáo Y học: Structural basis for the inhibitory efﬁcacy of efavirenz (DMP-266), MSC194 and PNU142721 towards the HIV-1 RT K103N mutant doc

... with the symmetry of space group C2221 Overall hydrophobic NNRTI interactions to wild-type and K103N mutant RT The interactions of Efavirenz, MSC194 and PNU142721 to wild-type RT and the K103N mutant ... study we present the structural indications for the role of K103 and N103 in drug binding and the structural implications for the inhib...

Ngày tải lên : 18/03/2014, 01:20

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Báo cáo khoa học: Structural basis for the recognition of complex-type biantennary oligosaccharides by Pterocarpus angolensis lectin ppt

... further oligosaccharides that are fragments of NA2F The structural information is complemented by thermodynamic parameters of binding determined by means of isothermal titration calorimetry for ... second conformation of the side chain of Glu221, which also adopts two conformations but not correlated with the anomeric form of the bound mannose is shown in dark gr...

Ngày tải lên : 23/03/2014, 11:20

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Báo cáo khoa học: H NMR study of the molecular structure and magnetic properties of the active site for the cyanomet complex of O2-avid hemoglobin from the trematode Paramphistomum epiclitum pdf

... CbHs CdHs CeHs CfH NH CaH CbH CdHs CeHs NH CaH CbH CdH NH CaH CbH CdHs CeHs CfH NH CaH CbH CbHÂ CdHs CeHs OH NH CaH CbH3 NH CaH CbH CcH3 NH CaH CbH CbHÂ CcH CdH3 CdH3Â NH CaH CbH3 NH CaH CbH ... NH CaH CbH CbHÂ NdH NH CaH CbH CcH3 NH CaH CbH CcH3 CcH3Â NH CaH CbH CbH CdHs CfH NH CaH CaHÂ NH CbH CbHÂ CdHs CeHs CfH NH CaH CbH CdHs CeHs CfH NH CaH CbHs CcH CeH3 CaH CbH CcHs CcHÂ CdH3 3.25 ... po...

Ngày tải lên : 23/03/2014, 17:22

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