In vitro study of surface functionalization of titanium substrates for potential enhancement of osseointegration and reduction of bacterial infection

... IN VITRO STUDY OF SURFACE FUNCTIONALIZATION OF TITANIUM SUBSTRATES FOR POTENTIAL ENHANCEMENT OF OSSEOINTEGRATION AND REDUCTION OF BACTERIAL INFECTION HU XUEFENG (B.Eng., ... 2007).Therefore, new strategies of surface functionalization of titanium implants have been investigated with the aim of improving osseointegration 2.4.1 Enhancement...

Ngày tải lên: 10/09/2015, 09:13

... successful clinical application Noteworthy, the evaluation of the interaction of cells and implanted materials must take into account other parameters in addition to the analysis of maintenance of cell ... (Takara Biomedicals, Japan); anti-human vitronectin, anti-human vitronectin receptor and anti-human VE-cadherin (Chemicon International, USA); anti-human αsmooth muscle actin (I...

Ngày tải lên: 11/08/2014, 20:20

... of pravastatin in human erythrocytes The current work studies effect of time, temperature as well as drug concentration on the process of pravastatin loading into human erythrocytes by endocytosis ... characterization of pravastatin loaded erythrocytes Hematological Indices To determine the effect of loading process on erythrocytes, normal erythrocytes, erythrocyt...

Ngày tải lên: 25/10/2012, 11:10

... type II and aggrecan core protein was steadily expressed in fibrin/ PLGA and PLGA Interestingly, suppression of collagen type I was observed in fibrin/ PLGA and PLGA at weeks and weeks β-actin gene ... that fibrin would be an ideal cell carrier/transplantation matrix and to enhance in vitro chondrogenesis of rabbit articular chondrocytes by mean of morphologi...

Ngày tải lên: 20/06/2014, 01:20

... light of these many uncertainties, we carried out an invitro study of the effect of various antirheumatoid drugs alone and in combination on the proliferation of osteogenic cells derived from the ... proliferation In addition, we found that the effects of these drugs on cell proliferation can vary between donors Although on average Dexamethasone increased...

Ngày tải lên: 20/06/2014, 01:20

... Contribution of a xenograft bone plate-screw system in dogs 195 Discussion Fig The comparison of stiffness for xenograft bone platescrew following biomechanical test of the data, the software (Statistica'99; ... [1], the usability of bone as a spinal implant or instrument in the spinal surgery is possible Compare to the group I average stiffness values,...

Ngày tải lên: 07/08/2014, 20:23

... within a small number of cells in monolayer culture Following injection into NP tissue explants, MSCs stained strongly positive for type II collagen and matrix staining in the vicinity of the injected ... viability/metabolic activity of injected mesenchymal stem cells Photomicrographs representative of caspase immunopositivity and polyAcells mRNA staining in...

Ngày tải lên: 09/08/2014, 01:22

... be consistent in vitro and in vivo The direct negative effects of indomethacin are mainly reflected by an inhibition of proteoglycan synthesis and diminished retention of these newly formed proteoglycans ... proteoglycan turnover (Table 1): low proteoglycan synthesis, high proteoglycan release (both newly formed proteoglycans and resident proteoglycans) and dimin...

Ngày tải lên: 09/08/2014, 07:20

... secretion of soluble mediators by RASF with the use of custom antibody-based cytokine membrane arrays A proteomic analysis of these supernatants revealed an increased secretion of cytokines/ Available ... from RASF into the supernatant (RASFsn) and induced the catabolic and inflammatory response of chondrocytes after stimulation Protein analysis of the supernatant of RASF was...

Ngày tải lên: 09/08/2014, 10:22

... than the inhibition of cyclooxigenase activity, typical of nonsteroidal anti-inflammatory drugs (NSAIDs), and thus devoid of irritant effects on the gastric mucosa and suitable for use in chronic ... stimulus minus basal adhesion, and b is adhesion elicited by stimulus minus basal adhesion Prostacyclin and Prostaglandin E2 enzyme immunoassay The effect of IL-1α on th...

Ngày tải lên: 11/08/2014, 08:21

... In vitro and In vivo study of ABT- 869 in treatment acute myeloid leukemia (AML) alone or in combination with chemotherapy or HDAC inhibitors: insight into molecular mechanism and biologic characterization ... target of STAT3 3.3.9 In vivo efficacy of IDR E804 in combination with ABT- 869 for treatment of MV4-1...

Ngày tải lên: 11/09/2015, 09:06

... the herceptin conjugated liposomes Thus the herceptin conjugated Vitamin E TPGS coated liposomes showed greater potential for sustained and targeted chemotherapy in the treatment of HER2 over expressing ... have been discovered and developed since the past few decades Together with the problems faced in traditional ways in which cancer patients are treated, this regi...

Ngày tải lên: 09/10/2015, 11:18

... that acute doxorubicin administration decreased COL- 3 oral bioavailability and prolonged COL- 3 elimination in rats[1 23] In the present study, a potential combination therapy of COL- 3 and tamoxifen ... combination of tamoxifen and COL- 3 is rational, based on the marked antitumor activity of both agents against a variety of solid tumors, suc...

Ngày tải lên: 09/10/2015, 11:24

... numbers of samples are involved (Section 5.4) Analysis, sequencing and in vitro expression of PCR products 93 5.4 Direct DNA sequencing of PCR products Once a PCR product has been cloned into a ... primer in excess continues to allow linear accumulation of one strand of DNA suitable for subsequent DNA sequencing Analysis, sequencing and in vitro...

Ngày tải lên: 25/10/2013, 22:20

... of the triangular prism binding pocket, with its amino sugar anchored Expansion of DNA repeat sequences in the major groove of the DNA pointing toward the 3¢ -bulge- flanking base pair We were interested ... as the ligand–nucleic acid complex is formed To gain insight into the binding of drugs to bulge DNA, several bulgecontaining oligonucleotides were selected as binding...

Ngày tải lên: 07/03/2014, 06:20