Study of aptamer for cancer therapeutics

... STUDY OF APTAMER FOR CANCER THERAPEUTICS TAN LIHAN (B ENG, NATIONAL UNIVERSITY OF SINGAPORE) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY DEPARTMENT OF CHEMICAL AND ... AuNP based assay to study peptide -aptamer interaction, 2) the modification of aptamer to tailor drug delivery to cancer cells (but not macrophages), and 3) the study of bladder...

Ngày tải lên: 09/09/2015, 10:21

... prospective randomized comparison of and 12 cycles of Cyclophosphamide, Adriamycin and Cisplatin in advanced epithelial ovarian cancer: a Danish ovarian study Group Trial (DACOVA) Gynecol Oncol ... arm completed cycles of first-line chemotherapy only, while an additional cycles of polychemotherapy with FU followed by Cisplatin were proposed for the 61 patients in the Cis...

Ngày tải lên: 03/11/2012, 09:57

... a recurrence in the univariate analysis This analysis revealed radiotherapy at recurrence as a significantly worse prognostic factor compared with adjuvant radiotherapy The addition of radiotherapy ... are members of the "Rare Cancer Network" [12] This study aims to contribute to an assessment of the therapeutic value of radiotherapy in the multimoda...

Ngày tải lên: 09/08/2014, 10:21

... behind this study was based on the findings that angiotensin converting enzyme and angiotensin II are both involved in the pulmonary vascular remodelling associated with hypoxic pulmonary hypertension ... 23(89):57-72 Yu PN, Lovejoy FW Jr, Joos HA, Nye RE Jr, McCann WS: Studies of pulmonary hypertension I Pulmonary circulatory dynamics in patients with pulmonary emphysem...

Ngày tải lên: 12/08/2014, 18:22

... as a tool of implementing plans and achieving teaching goals, teacher talk plays a vital important role in language learning As Nunan (1991) points out that teacher talk is of crucial importance, ... education, and personal qualities Above all, the language teacher brings to it a language background and A study of teachers’ instructions for group work in 2nd yea...

Ngày tải lên: 28/03/2015, 08:58

... Comparative study of 64Cu/NOTA-[D-Tyr6,βAla11,Thi13,Nle14]BBN(6-14) β monomer and dimers for prostate cancer PET imaging Patrick Fournier1, Véronique Dumulon-Perreault1, Samia Ait-Mohand1, ... (2,000 to 2,500 Ci/mmol) for NOTA -monomer, and 93 to 130 TBq/mmol (2,500 to 3,500 Ci/mmol) for 64Cu/NOTA -dimers and Figure shows radio-HPLC chromatograms of 64Cu/NOTAmon...

Ngày tải lên: 21/06/2014, 17:20

... during and after therapy .12 Prostate cancer patients who had failed standard therapy were enrolled at William Beaumont, Royal Oak, MI and Summa Health Systems, Akron, OH Standard therapy was defined ... capsule every two hours for six doses followed by two capsules at bedtime for a total of ten capsules per day Following the 12 week study, two of the three “non-...

Ngày tải lên: 08/08/2014, 17:20

... Early stage breast cancer can be treated with breast conserving therapy and accelerated partial breast irradiation using electronic brachytherapy Treatment was well tolerated, and these early outcomes ... RR, Wazer DE, Nag S, American Brachytherapy Society: Accelerated partial breast irradiation: an updated report from the American Brachytherapy Society Brachyther...

Ngày tải lên: 09/08/2014, 01:24

... introduced: a total dose of 29 Gy was delivered with twice daily fractions of 2.9 Gy; an interval of at least hours between the daily fractions was mandatory to allow recovery of normal tissue and the total ... late toxicity compared to five fractions of Gy: radiotherapy was delivered in twice daily fractions of 2.9 Gy to a total...

Ngày tải lên: 09/08/2014, 10:20

... of potential markers for cancer stem cells in large cell neuroendocrine carcinoma of the lung An FFPE proteomic study Journal of Clinical Bioinformatics 2011 1:23 Submit your next manuscript to ... upon Tyne, U.K.), polyclonal rabbit anti CGA antibody (DAKO Japan, Kyoto, Japan) and monoclonal mouse anti SYN antibody (DAKO Japan, Kyoto, Japan) The staining...

Ngày tải lên: 10/08/2014, 09:22

... human salivary gland cancer cells Oral Oncol 2006, 42:593598 44 Hayashi M, Sakata M, Takeda T, Tahara M, Yamamoto T, Okamoto Y, Minekawa R, Isobe A, Ohmichi M, Tasaka K, Murata Y: Up-regulation ... normal tissues and for tackling ‘undruggable’ targets Technological advances, coupled with the availability of large siRNA and shRNA libraries, now make unbiased synthetic lethal screens...

Ngày tải lên: 11/08/2014, 12:20

... on the world as well as in Vietnam remain limited Due to the above issues, we implemented the study "The study in application of laparoscopic abdominoperineal resection for treatment of low rectal ... rectal cancer" with goals: Study lymphadenectomy in laparoscopic abdominoperineal resection for treatment of low rectal cancer Evaluat...

Ngày tải lên: 10/10/2014, 23:25

... 30 Yassin AE, Alsarra IA, Alanazi FK, et al New targeted -colon delivery system: in vitro and in vivo evaluation using x-ray imaging J Drug Target 2010; 18: 59-66 31 Alanazi FK, Yassin A, El-Badry ... Germany) Table 1, represents the exact composition of each of the prepared formula The effect of different formulation parameters, such as type of Dynasan, soyalicithin:Dynasan ratio,...

Ngày tải lên: 25/10/2012, 11:22

... deaths TABLE Characteristics of cases and two control groups: Population- based case -control study of smoking on risk of cancer deaths among Chinese men 1989–1991 Characteristic Cases No of subjects ... sex-matched living spouse control design as an alternative control selection for a nationwide population- based case -control study is valid and feasib...

Ngày tải lên: 26/10/2012, 09:48

... that is system capacity In Chapter 5, the MIMO -OFDM system capacity with imperfect feedback channel is investigated In Chapter 6, the capacity variances for OFDM systems over Rayleigh and Ricean ... 6) Chapter 2: OFDM systems and MIMO systems Since the thesis studies the channel estimation for OFDM systems and system capacity for MIMO -OFDM sy...

Ngày tải lên: 20/11/2012, 11:28