Computational modeling of cell signaling dynamics hypothesis management and parameter estimation methods applied to the akt pathway

... being modeled often contain poorly understood aspects Further, the temporal dynamics of cell signaling pathway is complex and unintuitive, as the dynamics of proteins in the pathways are often interdependent ... state -of- the- art parameter estimation techniques Chapter Four has a special role in bridging the topic of “data-rich parameter estimation in Chapt...

Ngày tải lên: 09/09/2015, 10:18

Ngày tải lên: 28/03/2014, 15:20

... Quercus robur L and Q pe(Matt) Liebl: a multivariate approach to the hybrid problem Data acquisition analysis and interpretation Watsonia 12, 81-101 Rushton BS (1983) An analysis of variation of traea ... 18 and 25 mm in sessile oak This variation covers about 60% of the trees classified here as pedunculate oaks and only 30% of the sessile oaks The qu...

Ngày tải lên: 08/08/2014, 19:21

... role of miRNAs with respect to the complicated regulation of the transcriptome and signal transduction Although miRNAs and well-established cell signaling pathways have been the subject of recent ... have focused upon the role of miRNAs in regulatory network of various cell signaling pathways We summarize the current knowledge of the interdependence of miRNA...

Ngày tải lên: 14/02/2014, 19:20

... illustrates resulting word maturity curves for some of the words (" !"#$%&'()#*(+% merging using Procrustes Alignment, the comparison of word meanings becomes a simple problem of comparing word vectors ... schools, including: o Words known by most children in grade o Words known by 40-80% of children in grade o Words known by 40-80% of children in grade o Words known by fewer...

Ngày tải lên: 07/03/2014, 22:20

Ngày tải lên: 23/03/2014, 17:20

Ngày tải lên: 13/11/2014, 10:13

... of various redox signals into an effective second messenger system It is likened to phosphorylation/dephosphrylation process mediated by kinases and phosphatases since the process of S- nitrosylation ... blood and tissue and thus NO2˙- is thought to serve as part of NO˙ storage system in biological systems (Lundberg JO and Weitzberg E, 2005 & 2010) NO˙ storage system co...

Ngày tải lên: 09/09/2015, 17:56

... disregarded as a wastewater source Mass discharge coefficients relating to quality of the runoff water to the land use and amount of rainfall are given in Table Miscellaneous waste discharges occur into ... storm water runoff from the streets and gutters which is routed to the nearest waterway by storm water pipes, or it may consist of a mixture of storm water ru...

Ngày tải lên: 10/08/2014, 20:20

... nuclei, of chromatin distribution and of sites of lipid peroxidation in cells undergoing oxidative stress by nanoparticles Chromatin reorganization in cell nuclei and lipid peroxidation are critical ... and (b) of Fig Discussion In this study we present a versatile, simple and suitable approach to 3-D reconstruction of intracellular QD location and of changes...

Ngày tải lên: 11/08/2014, 00:22

... lack of activation and expression of CD38 and HLA-DR on CD4+ T cells correlates with long-term non-progression [9] The enumeration of CD4+ T- lymphocytes by flow cytometry is used routinely in the ... infection [41] These findings, together with ours, support the hypothesis that the CD8+ T cells from LNTP may have stronger cytotoxic activity than those from...

Ngày tải lên: 13/08/2014, 05:22

... model, a multidisciplinary approach and a specific team played a key role for education and for providing an early and appropriate sepsis management A large number of patients and a more detailed assessment ... contributions to study conception and design, acquisition of data, statistical analysis and has been involved in drafting the manuscript LD has made...

Ngày tải lên: 13/08/2014, 19:20

Ngày tải lên: 14/11/2014, 12:59

... Niranjayan, A Nallanathan and B Kannan, Modeling of Multiple Access Interference and BER Derivation for TH and DS UWB Multiple Access Systems , IEEE Transactions on Wireless communications, Aug ... Schemes”, Proc of Joint UWBST and IWUWBS 2004, May 2004 [3] S Niranjayan, A Nallanathan and B Kannan, A New Analytical Method for Exact Bit Error Rate Computa...

Ngày tải lên: 05/10/2015, 22:04

Ngày tải lên: 21/02/2014, 08:20